3,011 research outputs found

    Intertwined Order and Holography: The Case of Parity Breaking Pair Density Waves

    Get PDF
    Article / Letter to editorLeids Instituut Onderzoek Natuurkund

    Intertwined Order and Holography: The Case of Parity Breaking Pair Density Waves

    Get PDF
    Article / Letter to editorLeids Instituut Onderzoek Natuurkund

    Validity of the Generalized Second Law of Thermodynamics of the Universe Bounded by the Event Horizon in Brane Scenario

    Full text link
    In this paper, we examine the validity of the generalized second law of thermodynamics (GSLT) of the universe bounded by the event horizon in brane-world gravity. Here we consider homogeneous and isotropic model of the universe filled with perfect fluid in one case and in another case holographic dark energy model of the universe has been considered. The conclusions are presented point wise.Comment: 8 pages, the paper has been accepted in EPJC for publication. Conclusion has been modified an some references have been adde

    FRW Universe in Ho\~rava Gravity

    Full text link
    Recently, a field theoretic model for a UV complete theory of gravity has been proposed by Ho\~{r}ava. This theory is a non-relativistic renormalizable gravity theory which coincides with Einstein's general relativity at large distances. Subsequently L\"{u} et al have formulated the modified Friedmann equations and have presented a solution in vacuum. In the present work, we rewrite the modified FRW equations in the form of usual FRW equations in Einstein gravity and consequences has been analyzed. Also the thermodynamics of the FRW universe has been studied

    Entropic force and its cosmological implications

    Full text link
    We investigate a possibility of realizing the entropic force into the cosmology. A main issue is how the holographic screen is implemented in the Newtonian cosmology. Contrary to the relativistic realization of Friedmann equations, we do not clarify the connection between Newtonian cosmology and entropic force because there is no way of implementing the holographic screen in the Newtonian cosmology.Comment: 16 pages, no figures, version "Accepted for publication in Astrophysics & Space Science

    Cell nuclei detection using globally optimal active contours with shape prior

    Get PDF
    Cell nuclei detection in fluorescent microscopic images is an important and time consuming task for a wide range of biological applications. Blur, clutter, bleed through and partial occlusion of nuclei make this a challenging task for automated detection of individual nuclei using image analysis. This paper proposes a novel and robust detection method based on the active contour framework. The method exploits prior knowledge of the nucleus shape in order to better detect individual nuclei. The method is formulated as the optimization of a convex energy function. The proposed method shows accurate detection results even for clusters of nuclei where state of the art methods fail

    Proteome Dynamics with Heavy Water — Instrumentations, Data Analysis, and Biological Applications

    Get PDF
    The quantitative assessment of the synthesis of individual proteins has been greatly hindered by the lack of a high-throughput nonradioactive method. We recently developed a method that we call “proteome dynamics” and software that enables high-throughput kinetic analyses of peptides on a proteome-wide scale. Previous studies established that oral administration of heavy water (2H2O or deuterium oxide, D2O) is safe and well tolerated in humans. Briefly, a loading dose of 2H2O, a nonradioactive isotope, is administered in drinking water. 2H2O rapidly labels body water and transfers 2H from 2H2O to 2H-labeled amino acids, which incorporates into proteins dependent upon the rate of synthesis of the specific protein. Proteins are analyzed by high-resolution mass spectrometry and protein synthesis is calculated using specialized software. We have established the effectiveness of this method for plasma and mitochondrial proteins. We demonstrated that fasting has a differential effect on the synthesis rates of proteins. We also applied this method to assess the effect of heart failure on the stability of mitochondrial proteins. In this review, we describe the study design, instrumentation, data analysis, and biological application of heavy water-based proteome turnover studies. We summarize this chapter with the challenges in the field and future directions

    The thermodynamic evolution of the cosmological event horizon

    Full text link
    By manipulating the integral expression for the proper radius ReR_e of the cosmological event horizon (CEH) in a Friedmann-Robertson-Walker (FRW) universe, we obtain an analytical expression for the change \dd R_e in response to a uniform fluctuation \dd\rho in the average cosmic background density ρ\rho. We stipulate that the fluctuation arises within a vanishing interval of proper time, during which the CEH is approximately stationary, and evolves subsequently such that \dd\rho/\rho is constant. The respective variations 2\pi R_e \dd R_e and \dd E_e in the horizon entropy SeS_e and enclosed energy EeE_e should be therefore related through the cosmological Clausius relation. In that manner we find that the temperature TeT_e of the CEH at an arbitrary time in a flat FRW universe is Ee/SeE_e/S_e, which recovers asymptotically the usual static de Sitter temperature. Furthermore, it is proven that during radiation-dominance and in late times the CEH conforms to the fully dynamical First Law T_e \drv S_e = P\drv V_e - \drv E_e, where VeV_e is the enclosed volume and PP is the average cosmic pressure.Comment: 6 page

    Scalar-Tensor Theory of Gravity and Generalized Second Law of Thermodynamics on the Event Horizon

    Full text link
    In blackhole physics, the second law of thermodynamics is generally valid whether the blackhole is a static or a non-static one. Considering the universe as a thermodynamical system the second law of blackhole dynamics extends to the non-negativity of the sum of the entropy of the matter and the horizon, known as generalized second law of thermodynamics(GSLT). Here, we have assumed the universe to be bounded by the event-horizon or filled with perfect fluid and holographic dark energy in two cases. Thus considering entropy to be an arbitrary function of the area of the event-horizon, we have tried to find the conditions and the restrictions over the scalar field and equation of state for the validity of the GSLT and both in quintessence-era and in phantom-era in scalar tensor theory.Comment: 8 page

    Harvesting graphics power for MD simulations

    Get PDF
    We discuss an implementation of molecular dynamics (MD) simulations on a graphic processing unit (GPU) in the NVIDIA CUDA language. We tested our code on a modern GPU, the NVIDIA GeForce 8800 GTX. Results for two MD algorithms suitable for short-ranged and long-ranged interactions, and a congruential shift random number generator are presented. The performance of the GPU's is compared to their main processor counterpart. We achieve speedups of up to 80, 40 and 150 fold, respectively. With newest generation of GPU's one can run standard MD simulations at 10^7 flops/$.Comment: 12 pages, 5 figures. Submitted to Mol. Si
    corecore