Successive injections modulation of a direct three-phase to single-phase AC/AC converter for a contactless electric vehicle charger

This paper proposes a successive injection modulation (SIM) method for a direct three-phase to single-phase AC/AC converter of a contactless electric vehicle (EV) charger. The converter has a fewer bi-directional switches than a matrix converter without a neutral line connection. It operates using injection and free-wheeling oscillation commutations based on a zero-current switching mechanism. Analytical calculations were derived using a steady-state analysis. Simulation results were obtained to validate the calculations. The proposed modulation increases output power three times compared to a non-successive one with the same circuit setup.Peer reviewe

Model of ferromagnetic clusters in amorphous rare earth and transition metal alloys

10.1063/1.1371005Journal of Applied Physics89128046-8053JAPI

A model for magnetic ordering in inhomogeneous amorphous RE-Fe-Al alloys

Journal of Magnetism and Magnetic Materials226-230PART II1504-1506JMMM

Magnetic and Moessbauer study of melt-spun Nd60Fe30Al10

10.1016/S0304-8853(00)00703-4Journal of Magnetism and Magnetic Materials2242143-152JMMM

Cancer-testis antigen GAGE-1 expression and serum immunoreactivity in hepatocellular carcinoma

Aim: To explore the use of cancer‑testis antigen G antigen 1 (GAGE‑1) in the diagnosis and potential therapeutic targeting of hepatocellular carcinoma (HCC), we measured the expression of GAGE‑1 protein levels in HCC tissues and its serum immunoreactivity in HCC patients.Materials and Methods: We detected the expression of GAGE‑1 protein in HCC by immunohistochemistry (IHC). We then analyzed the clinical significance of GAGE‑1 expression in HCC with respect to clinicopathological parameters. We observed positive anti‑GAGE‑1 antibody reactivity in HCC patient serum, liver cirrhosis patients (LC), hepatitis B patients (HB), and normal human individuals (NHS) by enzyme‑linked immunosorbent assay.Results: The IHC results showed that the positive rates of GAGE‑1 protein expression in cancer tissues and adjacent tissues were 43.3% (26/60) and 5% (3/60), respectively. The expression level of GAGE‑1 protein in HCC tissues was significantly higher than that in tumor‑adjacent tissues (P < 0.05). Positive GAGE‑1 protein expression was not correlated with clinicopathological parameters (P > 0.05). Positive serum anti‑GAGE‑1 antibody reactivity in HCC patients, LC, HB, and NHS was 23.33% (14/59), 13.1% (8/61), 3.3% (2/60), and 3.4% (2/59), respectively. The frequency of anti‑GAGE‑1 antibody‑positive sera in HCC patients and LC was significantly different than that in HB and NHS (P < 0.01), but no significant differences were found between HCC patients and LC (P = 0.485) or between HB and NHS (P = 0.410). Positive anti‑GAGE‑1 antibody reactivity was not correlated with clinicopathological parameters (P > 0.05).Conclusion: These data illustrate that the GAGE‑1 protein exhibits moderate cancer‑restricted pattern of expression and immunogenicity, laying the foundation for the application of GAGE‑1 in immunotherapy and for the diagnosis of HCC.Keywords: Cancer‑testis antigen,G antigen 1, immunohistochemistry, serolog

The α component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development

We recently proposed that ciliary neurotrophic factor (CNTF) shares two receptor components with a generally acting cytokine, leukemia inhibitory factor (LIF), but that CNTF also requires a third receptor component (CNTFRα) that is mostly restricted to the nervous system in its expression. Here we demonstrate that a transfected CNTFRα gene is sufficient to confer CNTF responsiveness upon hemopoietic cells normally responsive only to LIF, providing evidence that CNTFRα is a required receptor component that uniquely characterizes CNTF-responding cells. Consistent with this notion, CNTFRα expression could be localized to neurons within all known peripheral targets of CNTF. CNTFRα was also widely expressed within neurons of the CNS, suggesting that CNTF has broader CNS actions than previously appreciated. However, in vivo localization of CNTFRα, as well as of CNTF itself, is consistent with a particularly important role for CNTF in motor function as well as during neuropoiesis