DLP-GAN: learning to draw modern Chinese landscape photos with generative adversarial network

Chinese landscape painting has a unique and artistic style, and its drawing technique is highly abstract in both the use of color and the realistic representation of objects. Previous methods focus on transferring from modern photos to ancient ink paintings. However, little attention has been paid to translating landscape paintings into modern photos. To solve such problems, in this paper, we (1) propose DLP-GAN (Draw Modern Chinese Landscape Photos with Generative Adversarial Network), an unsupervised cross-domain image translation framework with a novel asymmetric cycle mapping, and (2) introduce a generator based on a dense-fusion module to match different translation directions. Moreover, a dual-consistency loss is proposed to balance the realism and abstraction of model painting. In this way, our model can draw landscape photos and sketches in the modern sense. Finally, based on our collection of modern landscape and sketch datasets, we compare the images generated by our model with other benchmarks. Extensive experiments including user studies show that our model outperforms state-of-the-art methods.Comment: Corrected typo

The Inverted U-Shaped Association between Serum Vitamin D and Serum Uric Acid Status in Children and Adolescents: A Large Cross-Sectional and Longitudinal Analysis

Background: Serum vitamin D is associated with hyperuricemia. However, previous studies have been controversial, with limited focus on children and adolescents. Objective: This study aimed to examine the cross-sectional and longitudinal associations between serum vitamin D and serum uric acid (SUA) levels in children and adolescents. Methods: The cross-sectional survey comprised 4777 participants aged 6 to 18 years, while the longitudinal survey involved 1641 participants aged 6 to 12 years, all derived from an ongoing cohort study in Shenzhen, China. Restricted cubic splines were used to visualize the dose–response relationship between vitamin D and SUA and the risk of higher SUA status. Two-segment generalized linear models (GLM) and logistic models were used to assess the association between vitamin D and SUA and higher SUA status, respectively. The longitudinal analysis used GLM. Results: We observed an inverted U-shaped relationship between vitamin D and SUA (p-overall p-nonlinear = 0.0002), as well as the risk of higher SUA status (p-overall = 0.0054, p-nonlinear = 0.0015), with the vitamin D inflection point at 24.31 and 21.29 ng/mL, respectively. A 10 ng/mL increment in 25(OH)D3 levels, when below 20.92 ng/mL, was associated with a 68% rise in the risk of higher SUA status (OR: 1.68, 95%CI: 1.07–2.66). Conversely, when 25(OH)D3 levels were above or equal to 20.92 ng/mL, a 10 ng/mL increment was associated with a 45% reduction risk of higher SUA status (OR: 0.55, 95%CI: 0.36–0.84). Longitudinal analysis indicated that the annual change of SUA was from −4.80 (β, 95%CI: −10.74, 1.13) to −9.00 (β, 95%CI: −15.03, −2.99) and then to −6.77 (β, 95%CI: −12.83, −0.71, p for trend = 0.0212) μmol/L when increasing the quartile of vitamin D3. Conclusions: An inverse U-shaped relationship was observed between vitamin D and SUA as well as the risk of higher SUA status. Sufficient vitamin D levels appear to play a preventative role against the age-related increase in SUA. Ensuring adequate vitamin D levels may be beneficial in improving uric acid metabolism