Entanglement renormalization and integral geometry

We revisit the applications of integral geometry in AdS$_3$ and argue that the metric of the kinematic space can be realized as the entanglement contour, which is defined as the additive entanglement density. From the renormalization of the entanglement contour, we can holographically understand the operations of disentangler and isometry in multi-scale entanglement renormalization ansatz. Furthermore, a renormalization group equation of the long-distance entanglement contour is then derived. We then generalize this integral geometric construction to higher dimensions and in particular demonstrate how it works in bulk space of homogeneity and isotropy.Comment: 40 pages, 7 figures. v2: discussions on the general measure added, typos fixed; v3: sections reorganized, various points clarified, to appear in JHE

OPE of the stress tensors and surface operators

We demonstrate that the divergent terms in the OPE of a stress tensor and a surface operator of general shape cannot be constructed only from local geometric data depending only on the shape of the surface. We verify this holographically at d=3 for Wilson line operators or equivalently the twist operator corresponding to computing the entanglement entropy using the Ryu-Takayanagi formula. We discuss possible implications of this result.Comment: 20 pages, no figur

Unified analysis of finite-size error for periodic Hartree-Fock and second order M{\o}ller-Plesset perturbation theory

Despite decades of practice, finite-size errors in many widely used electronic structure theories for periodic systems remain poorly understood. For periodic systems using a general Monkhorst-Pack grid, there has been no comprehensive and rigorous analysis of the finite-size error in the Hartree-Fock theory (HF) and the second order M{\o}ller-Plesset perturbation theory (MP2), which are the simplest wavefunction based method, and the simplest post-Hartree-Fock method, respectively. Such calculations can be viewed as a multi-dimensional integral discretized with certain trapezoidal rules. Due to the Coulomb singularity, the integrand has many points of discontinuity in general, and standard error analysis based on the Euler-Maclaurin formula gives overly pessimistic results. The lack of analytic understanding of finite-size errors also impedes the development of effective finite-size correction schemes. We propose a unified analysis to obtain sharp convergence rates of finite-size errors for the periodic HF and MP2 theories. Our main technical advancement is a generalization of the result of [Lyness, 1976] for obtaining sharp convergence rates of the trapezoidal rule for a class of non-smooth integrands. Our result is applicable to three-dimensional bulk systems as well as low dimensional systems (such as nanowires and 2D materials). Our unified analysis also allows us to prove the effectiveness of the Madelung-constant correction to the Fock exchange energy, and the effectiveness of a recently proposed staggered mesh method for periodic MP2 calculations [Xing, Li, Lin, J. Chem. Theory Comput. 2021]. Our analysis connects the effectiveness of the staggered mesh method with integrands with removable singularities, and suggests a new staggered mesh method for reducing finite-size errors of periodic HF calculations

Top quark pair production at small transverse momentum in hadronic collisions

We investigate the transverse momentum resummation for top quark pair production at hadron colliders using the soft-collinear effective theory and the heavy-quark effective theory. We derive the factorization formula for $t\bar{t}$ production at small pair transverse momentum, and show in detail the procedure for calculating the key ingredient of the factorization formula: the next-to-leading order soft functions. We compare our numerical results with experimental data and find that they are consistent within theoretical and experimental uncertainties. To verify the correctness of our resummation formula, we expand it to the next-to-leading order and the next-to-next-to-leading order, and compare those expressions with the exact fixed-order results numerically. Finally, using the results of transverse momentum resummation, we discuss the transverse-momentum-dependent forward-backward asymmetry at the Tevatron.Comment: 39 pages, 7 figures, 1 table; final version in PR

The next-to-next-to-leading order soft function for top quark pair production

We present the first calculation of the next-to-next-to-leading order threshold soft function for top quark pair production at hadron colliders, with full velocity dependence of the massive top quarks. Our results are fully analytic, and can be entirely written in terms of generalized polylogarithms. The scale-dependence of our result coincides with the well-known two-loop anomalous dimension matrix including the three-parton correlations, which at the two-loop order only appear when more than one massive partons are involved in the scattering process. In the boosted limit, our result exhibits the expected factorization property of mass logarithms, which leads to a consistent extraction of the soft fragmentation function. The next-to-next-to-leading order soft function obtained in this paper is an important ingredient for threshold resummation at the next-to-next-to-next-to-leading logarithmic accuracy.Comment: 34 pages, 9 figures; v2: added references, matches the published versio

Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis

Medicinal plants as a rich pool for developing novel small molecule therapeutic medicine have been used for thousands of years. Carnosol as a bioactive diterpene compound originated from Rosmarinus officinalis (Rosemary) and Salvia officinalis, herbs extensively applied in traditional medicine for the treatment of multiple autoimmune diseases (1). In this study, we investigated the therapeutic effects and molecule mechanism of carnosol in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). Carnosol treatment significantly alleviated clinical development in the myelin oligodendrocyte glycoprotein (MOG35–55) peptide-induced EAE model, markedly decreased inflammatory cell infiltration into the central nervous system and reduced demyelination. Further, carnosol inhibited Th17 cell differentiation and signal transducer and activator of transcription 3 phosphorylation, and blocked transcription factor NF-κB nuclear translocation. In the passive-EAE model, carnosol treatment also significantly prevented Th17 cell pathogenicity. Moreover, carnosol exerted its therapeutic effects in the chronic stage of EAE, and, remarkably, switched the phenotypes of infiltrated macrophage/microglia. Taken together, our results show that carnosol has enormous potential for development as a therapeutic agent for autoimmune diseases such as MS