1,588 research outputs found
Ours to Displace, Ours to Protect : The Borderlands of American Indian Histories, Whiteness, and the Wilderness Ideal
\u27 Ours to Displace, Ours to Protect : The Borderlands of American Indian Histories, Whiteness, and the Wilderness Ideal\u27 is featured in the journal Tapestries: Interwoven voices of local and global identities, volume 4
SB50-17/18 Resolution Amending Elections Bylaws
This resolution passed unanimously on a roll call vote during the May 2, 2018 meeting of the Associated Students of the University of Montana (ASUM)
Providence, Emotion and Self-Writing in England, c.1660 â c.1720
This thesis offers a new interpretation of providentialism in late seventeenth- and early eighteenth-century England. Historians have seen this as a transitional period in providential belief and expression, between heightened engagement and gradual decline, and have provided us with many perspectives on the changing role of providence in English culture. But we still have yet to understand fully the role of providence in individual lives, where change occurred at an experiential and quotidian level. This thesis aims to fill this historiographical gap by examining practical, subjective and individual experiences of providentialism. Drawing on first-person narratives such as diaries and memoirs, conceptualised as sites of personal agency, it sheds light at the micro-level on broader shifts in providential belief and thought. These primary sources show how individuals exercised a personal providentialism, writing their relationship with Godâs providence into their own emerging sense of self. Investigation of the emotional resonances of providentialism also emphasizes its centrality to inner lives and personal identity, characterised by subtle but significant modes of feeling. Several case studies demonstrate how people constantly shaped and re-shaped themselves, and moulded ideas and beliefs relating to providence to fit particular social and religious circumstances and changing intellectual concerns. Providentialism is therefore shown to be elastic and subjective â a subjectivity that ensured the adaptability and durability of the concept of providence in an era of atheism, science and expanding secular authority. Far from seeing this period as a stage in an inexorable decline, the thesis shows how people continued to find uses for providence in creative and imaginative ways to make sense of themselves and their world in the late seventeenth and early eighteenth centuries
A comparison of two alternative methods for determining loss of future earnings following personal injuryĂ
The law provides that any person injured through the fault of another can claim monetary compensation in the form of damages. Restitutio in integrum defines the objective and measure of damages. Damages in respect of loss of future earnings comprise the product of an estimated annual loss and an estimated number of years purchase. Estimates are made by means of intuition and precedent with little reference to labour economics. Damages calculated under an alternative methodology incorporating age-earnings profiles and conditional employment rates are compared with damages awarded in 100 adjudicated cases to reveal systematic and substantial under-compensation under the court method.
Pregnancy risk stratification using DESI-MS profiling of vaginal mucosa
Preterm birth is the leading cause of childhood mortality. Despite decades of research, the pathophysiology of spontaneous preterm birth (SPTB) remains poorly understood. Prevention strategies are limited by our inability to reliably predict women at risk and stratify depending on underlying aetiology.
There is an established association between ascending vaginal infection and SPTB. More recently, highly diverse vaginal bacterial communities deplete of Lactobacillus species have been associated with SPTB. However, not all pregnant women with such community structures deliver preterm, highlighting the importance of individual host response. Medical swabs are routinely used for microbiological screening with culture-based techniques. However, these are time-consuming, have a narrow focus for specific microbes and provide no information regarding host response. We hypothesised that metabolic profiling of cervico-vaginal mucosa (CVM) may offer the ability to assess interactions between the vaginal microbiota and the pregnant host that are useful for prediction and stratification of SPTB risk.
To address this hypothesis, we developed a technique using DESI-MS that enabled rapid acquisition of metabolic information directly from vaginal swabs. In Chapter 3, method optimisation is described and its capacity to detect variations in the CVM associated with physiological changes in the host (e.g. pregnancy) and disruptions in bacterial community compositions during pregnancy (e.g. bacterial vaginosis) are presented.
The DESI-MS swab profiling approach was then used to characterise and compare CVM metabolic profiles associated with SPTB risk (Chapter 4). These results showed that the CVM metabolome associated with subsequent SPTB was highly variable, reflecting the heterogeneity of SPTB aetiology. In support of this, DESI-MS more effectively discriminated samples with differing severity of SPTB (early vs late) and phenotypes (SPTL and PPROM).
In Chapter 5, DESI-MS profiling of CVM was shown to facilitate prediction of PPROM as well as enable its robust diagnosis. DESI-MS also had capacity to characterise microbial compositions following PPROM suggesting its potential to assist in directed treatment strategies based on underlying aetiology.
This thesis highlights the predictive and therapeutic potential of DESI-MS in pregnancy.Open Acces
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