Properties of a hand-printed Chinese character recognizer based on contexted vector quantization

A hand-printed Chinese character recognizer based on Contextual Vector Quantization (CVQ) has been built previously. In this paper, several properties of the recognizer will be discussed and the recognizer of 4516 Chinese characters has a successful rate of 91.0%. Then the output of the recognizer is passed to a language model which when applied to recognize a passage of about 1200 characters raises the rate from 91.5% to 97.5%.published_or_final_versio

Return to work after stroke in Hong Kong. Part 2: a psychosocial perspective

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Ring-type electric current sensor based on ring-shaped magnetoelectric laminate of epoxy-bonded Tb₀.₃Dy₀.₇Fe₁.₉₂ short-fiber/NdFeB magnet magnetostrictive composite and Pb(Zr, Ti)O₃ piezoelectric ceramic

Author name used in this publication: S. L. Ho2009-2010 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Return to work after stroke in Hong Kong. Part 1: a biological perspective

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Haemorrhagic stroke vs ischaemic stroke: length of stay and functional outcome measures in stroke survivors

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Cyp26b1 mediates differential regulation of RA signaling in neural progenitor populations along the anteriorposterior axis of the adult spinal cord

Poster Session - Neural Regeneration: no. 64DMM 2011 entitled: Re-engineering Regenerative MedicineNeural stem cells from the adult subventricular zone (SVZ) are highly heterogeneous, with their position of origin being a key factor in determining the neuronal subtype they can give rise to. Whether this diversity extends to other regions in the adult CNS has not been demonstrated. In vitro studies with directed neuronal differentiation of ES cells suggest that subtype specification may be regulated by the positional identity present in the ES‐derived cell, since altering the positional identity leads to corresponding changes in motor neuron subtype. This limited plasticity suggests the position identity of the original stem cell source is a critical factor for the generation of the desired neuronal subtype. The adult spinal cord consists of endogenous stem/progenitor cells which are …postprin

Cyp26b1 mediates differential neurogenicity in axial-specific populations of adult spinal cord progenitor cells

Utilization of endogenous adult spinal cord progenitor cells (SCPCs) for neuronal regeneration is a promising strategy for spinal cord repair. To mobilize endogenous SCPCs for injury repair, it is necessary to understand their intrinsic properties and to identify signaling factors that can stimulate their neurogenic potential. In this study, we demonstrate that adult mouse SCPCs express distinct combinatorial Hox genes and exhibit axial-specific stem cell properties. Lumbar-derived neurospheres displayed higher primary sphere formation and greater neurogenicity compared with cervical- and thoracic-derived neurospheres. To further understand the mechanisms governing neuronal differentiation of SCPCs from specific axial regions, we examined the neurogenic responses of adult SCPCs to retinoic acid (RA), an essential factor for adult neurogenesis. Although RA is a potent inducer of neuronal differentiation, we found that RA enhanced the generation of neurons specifically in cervical- but not lumbar-derived cells. We further demonstrate that the differential RA response was mediated by the RA-degrading enzyme cytochrome P450 oxidase b1 Cyp26b1. Lumbar cells express high levels of Cyp26b1 and low levels of the RA-synthesizing enzyme retinaldehyde dehydrogenase Raldh2, resulting in limited activation of the RA signaling pathway in these cells. In contrast, low Cyp26b1 expression in cervical spinal cord progenitor cells allows RA signaling to be readily activated upon RA treatment. The intrinsic heterogeneity and signaling factor regulation among adult SCPCs suggest that different niche factor regimens are required for site-specific mobilization of endogenous SCPCs from distinct spatial regions of the spinal cord for injury repair.published_or_final_versio

Prediction of recovery of swallowing disorder in stroke patients after rehabilitation

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Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer

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Outcome of neurogenic dysphagia in stroke patients

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