16 research outputs found
Comparisons of energy sources for autonomous in-car wireless tags for asset tracking and parking applications
AbstractThis study compares the energy available on the car dashboard for powering in-car wireless tags for asset tracking and parking applications. Three energy sources available on the dashboard of a vehicle were investigated, i.e. vibration energy, thermal energy and light energy. The area available for the energy harvester is the same as a credit card (85×54mm2). Simulations were carried out to estimate the potential electrical power that can be generated from the three energy sources. It was found that a vibration harvester can generate tens of μW under all weather conditions. The other two types of energy harvesters can generate tens of mW on a sunny day. However, the output power of a thermogenerator drops to 0 while the power density of a solar cell drops by up to 40% on an overcast or rainy day
A comparison of power output from linear and nonlinear kinetic energy harvesters using real vibration data
An automated design flow for vibration-based energy harvester systems
This paper proposes, for the first time, an automated energy harvester design flow which is based on a single HDL software platform that can be used to model, simulate, configure and optimise energy harvester systems. A demonstrator prototype incorporating an electromagnetic mechanical-vibration-based micro-generator and a limited number of library models has been developed and a design case study has been carried out. Experimental measurements have validated the simulation results which show that the outcome from the design flow can improve the energy harvesting efficiency by 75%
A comparison of power output from linear and non-linear kinetic energy harvesters using real vibration data
The design of vibration energy harvesters (VEHs) is highly dependent upon the characteristics of the environmental vibrations present in the intended application. VEHs can be linear resonant systems tuned to particular frequencies or non-linear systems with either bi-stable operation or a Duffing-type response. This paper provides detailed vibration data from a range of applications, which has been made freely available for download through the Energy Harvesting Network’s online data repository. In particular, this research shows that simulation is essential in designing and selecting the most suitable vibration energy harvester for particular applications. This is illustrated through C-based simulations of different types of VEHs, using real vibration data from a diesel ferry engine, a combined heat and power pump, a petrol car engine and a helicopter. The analysis shows that a bistable energy harvester only has a higher output power than a linear or Duffing-type nonlinear energy harvester with the same Q-factor when it is subjected to white noise vibration. The analysis also indicates that piezoelectric transduction mechanisms are more suitable for bistable energy harvesters than electromagnetic transduction. Furthermore, the linear energy harvester has a higher output power compared to the Duffing-type nonlinear energy harvester with the same Q factor in most cases. The Duffing-type nonlinear energy harvester can generate more power than the linear energy harvester only when it is excited at vibrations with multiple peaks and the frequencies of these peaks are within its bandwidth. Through these new observations, this paper illustrates the importance of simulation in the design of energy harvesting systems, with particular emphasis on the need to incorporate real vibration data
Facile Preparation of Reduction-Responsive Micelles Based on Biodegradable Amphiphilic Polyurethane with Disulfide Bonds in the Backbone
In this paper, we synthesized a biodegradable amphiphilic polymer of polyurethane-polyethylene glycol with disulfide bonds in the main chain (PEG-PU(SS)-PEG). DLS and SEM showed that the polymer could self-assemble into micelles in aqueous solution and could be used to load the hydrophobic anticancer drug DOX. Intriguingly, drug release in vitro indicated that DOX-loaded PEG-PU(SS)-PEG micelles had good stability under the extracellular physiological environment, but the disulfide bonds broke rapidly and DOX was released quickly under the intracellular reducing conditions. CCK-8 assays showed that DOX-loaded PEG-PU(SS)-PEG micelles had a high in vitro antitumor activity in C6 cells, whereas blank PEG-PU(SS)-PEG micelles were nontoxic to C6 cells. It was also found that there was strong and persistent accumulation of DOX-loaded PEG-PU(SS)-PEG as compared with PEG-PU-PEG both by the cell internalization tests and the flow cytometry measurements. Hence, PEG-PU(SS)-PEG micelles will have a potential use for clinical treatment of cancer in the future
Facile Preparation of Reduction-Responsive Micelles Based on Biodegradable Amphiphilic Polyurethane with Disulfide Bonds in the Backbone
Reduction-responsive PEtOz-SS-PCL micelle with tailored size to overcome blood–brain barrier and enhance doxorubicin antiglioma effect
Novel Insights into the circRNA-Modulated Developmental Mechanism of Western Honey Bee Larval Guts
Circular RNAs (circRNAs) are a class of novel non-coding RNAs (ncRNAs) that play essential roles in the development and growth of vertebrates through multiple manners. However, the mechanism by which circRNAs modulate the honey bee gut development is currently poorly understood. Utilizing the transcriptome data we obtained earlier, the highly expressed circRNAs in the Apis mellifera worker 4-, 5-, and 6-day-old larval guts were analyzed, which was followed by an in-depth investigation of the expression pattern of circRNAs during the process of larval guts development and the potential regulatory roles of differentially expressed circRNAs (DEcircRNAs). In total, 1728 expressed circRNAs were detected in the A. mellifera larval guts. Among the most highly expressed 10 circRNAs, seven (novel_circ_000069, novel_circ_000027, novel_circ_000438, etc.) were shared by the 4-, 5-, and 6-day-old larval guts. In addition, 21 (46) up-regulated and 22 (27) down-regulated circRNAs were, respectively, screened in the Am4 vs. Am5 (Am5 vs. Am6) comparison groups. Additionally, nine DEcircRNAs, such as novel_circ_000340, novel_circ_000758 and novel_circ_001116, were shared by these two comparison groups. These DEcircRNAs were predicted to be transcribed from 14 and 29 parental genes; these were respectively annotated to 15 and 22 GO terms such as biological regulation and catalytic activity as well as 16 and 21 KEGG pathways such as dorsoventral axis formation and apoptosis. Moreover, a complicated competing endogenous RNA (ceRNA) network was observed; novel_circ_000838 in the Am4 vs. Am5 comparison group potentially targeted ame-miR-6000a-3p, further targeting 518 mRNAs engaged in several developmental signaling pathways (e.g., TGF-beta, hedgehog, and wnt signaling pathway) and immune pathways (e.g., phagosome, lysosome, and MAPK signaling pathway). The results demonstrated that the novel_circ_000838-ame-miR-6000a-3p axis may plays a critical regulatory part in the larval gut development and immunity. Furthermore, back-splicing sites of six randomly selected DEcircRNAs were amplified and verified by PCR; an RT-qPCR assay of these six DEcircRNAs confirmed the reliability of the used high-throughput sequencing data. Our findings provide a novel insight into the honey bee gut development and pave a way for illustration of the circRNA-modulated developmental mechanisms underlying the A. mellifera worker larval guts