Interpretation of the post-surgical Somatostatin Receptor Scintigram of a Primary Neuroendocrine Tumor of the Thymus: a case report and literature review

A case of a thymic neuroendocrine tumor and the interpretation problems in a post-surgical Somatostatin Receptor Scintigraphy are presented. In a 53-year-old man with superior vena cava obstruction syndrome an atypical carcinoid of the thymus (neuroendocrine carcinoma of intermediate grade 2), was found at surgery. During his first year of follow-up a Somatostatin Receptor Scintigraphy was recommended. An area of abnormal concentration of the radiopharmaceutical was revealed in the mediastinum at this time. A thorough understanding of the mechanisms of the radiopharmaceutical uptake and of the various clinical settings in which uptake can occur are essential for a proper evaluation of the scintigraphic findings and result in the optimal use of this valuable modality. The literature review provides an overview of this rare type of tumor and insight into the clinical significance of Somatostatin Receptor Scintigraphy

SPECT and PET Imaging of Meningiomas

Meningiomas arise from the meningothelial cells of the arachnoid membranes. They are the most common primary intracranial neoplasms and represent about 20% of all intracranial tumors. They are usually diagnosed after the third decade of life and they are more frequent in women than in men. According to the World Health Organization (WHO) criteria, meningiomas can be classified into grade I meningiomas, which are benign, grade II (atypical) and grade III (anaplastic) meningiomas, which have a much more aggressive clinical behaviour. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are routinely used in the diagnostic workup of patients with meningiomas. Molecular Nuclear Medicine Imaging with Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) could provide complementary information to CT and MRI. Various SPECT and PET tracers may provide information about cellular processes and biological characteristics of meningiomas. Therefore, SPECT and PET imaging could be used for the preoperative noninvasive diagnosis and differential diagnosis of meningiomas, prediction of tumor grade and tumor recurrence, response to treatment, target volume delineation for radiation therapy planning, and distinction between residual or recurrent tumour from scar tissue

The cientificWorldJOURNAL Review Article SPECT and PET Imaging of Meningiomas

Meningiomas arise from the meningothelial cells of the arachnoid membranes. They are the most common primary intracranial neoplasms and represent about 20% of all intracranial tumors. They are usually diagnosed after the third decade of life and they are more frequent in women than in men. According to the World Health Organization (WHO) criteria, meningiomas can be classified into grade I meningiomas, which are benign, grade II (atypical) and grade III (anaplastic) meningiomas, which have a much more aggressive clinical behaviour. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are routinely used in the diagnostic workup of patients with meningiomas. Molecular Nuclear Medicine Imaging with Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) could provide complementary information to CT and MRI. Various SPECT and PET tracers may provide information about cellular processes and biological characteristics of meningiomas. Therefore, SPECT and PET imaging could be used for the preoperative noninvasive diagnosis and differential diagnosis of meningiomas, prediction of tumor grade and tumor recurrence, response to treatment, target volume delineation for radiation therapy planning, and distinction between residual or recurrent tumour from scar tissue

Ecological and geochemical research of natural environment in Bakchar iron]ore deposit area (Tomsk region)

Currently entering this field in operation will lead to significant changes in geological environment. State of geological survey for geological and economic estimate and commercial development of Bakchar iron site allow confirming that the natural and industrial system at an early stage of development is formed in the area. So, it is possible to explore it. The value of current information describing a kind of natural environment, especially in remote areas, increased. The need to perform a full evaluation of the current geo-ecological state of Bakchar iron-ore deposit environment, identification of major natural and man-made factors forming the ecological and geological environment of the study area and involved in commercial development of resources determine the relevance of the research. The main aim of the research is to evaluate ecological and geochemical state of Bachar area according to a comprehensive study of natural environments at the initial stage of development of natural and man-made system associated with the proposed exploration of Bakchar mine. Methods and types of research: neutron activation analysis, emission spectral semi-quantitative analysis, atmogeochemical (sampling of snow cover), lithogeochemical (sampling of soil), hydrogeochemical (sampling of surface and groundwater), gidrolitogeochemical (sampling of sediments), biogeochemical (study of biosubstrate - hair of children), radiogeochemical studies (measurement of exposure dose, as well as the content of U, Th and K). Results. Based on the geochemical studies the authors give the geochemical characteristics of natural environment (soil, dust aerosols, sediments, surface water and groundwater, biosubstrates) which will assess the environmental change in the area of the proposed development of the deposit and use this data to monitor the organization

Ecological and geochemical research of natural environment in Bakchar iron]ore deposit area (Tomsk region)

Currently entering this field in operation will lead to significant changes in geological environment. State of geological survey for geological and economic estimate and commercial development of Bakchar iron site allow confirming that the natural and industrial system at an early stage of development is formed in the area. So, it is possible to explore it. The value of current information describing a kind of natural environment, especially in remote areas, increased. The need to perform a full evaluation of the current geo-ecological state of Bakchar iron-ore deposit environment, identification of major natural and man-made factors forming the ecological and geological environment of the study area and involved in commercial development of resources determine the relevance of the research. The main aim of the research is to evaluate ecological and geochemical state of Bachar area according to a comprehensive study of natural environments at the initial stage of development of natural and man-made system associated with the proposed exploration of Bakchar mine. Methods and types of research: neutron activation analysis, emission spectral semi-quantitative analysis, atmogeochemical (sampling of snow cover), lithogeochemical (sampling of soil), hydrogeochemical (sampling of surface and groundwater), gidrolitogeochemical (sampling of sediments), biogeochemical (study of biosubstrate - hair of children), radiogeochemical studies (measurement of exposure dose, as well as the content of U, Th and K). Results. Based on the geochemical studies the authors give the geochemical characteristics of natural environment (soil, dust aerosols, sediments, surface water and groundwater, biosubstrates) which will assess the environmental change in the area of the proposed development of the deposit and use this data to monitor the organization

Thymic neuroendocrine tumour (carcinoid): clinicopathological features of four patients with different presentation

Postizanje i održavanje zdravlja predstavljaju izazov današnjice i neraskidivo su povezani s očuvanjem profesionalnog djelovanja osobe, uključujući liječničku profesiju. Pitanje zdravlja liječnika postaje značajno u trenutku kada tjelesni poremećaj, poremećaj mentalnog zdravlja ili poremećaj vezan uz uzimanje sredstava ovisnosti interferira s mogućnošću kompetentnog i sigurnog obavljanja liječničkog zanimanja, odnosno pružanja kvalitetne i sigurne skrbi za pacijente. Cilj ovog rada bio je dati pregled suvremenih spoznaja o povezanosti zdravlja liječnika i kvalitete skrbi u obiteljskoj medicini, s posebnim osvrtom na preventivne aktivnosti i moguće intervencije u svrhu očuvanja zdravlja liječnika. Rezultati istraživanja pokazuju kako zdravlje liječnika obiteljske medicine može biti narušeno u svim segmentima kao i u osoba u općoj populaciji, uz nešto veću učestalost poremećaja mentalnog zdravlja. Liječnici mogu bolovati od jednog ili više medicinskih stanja koja mogu i ne moraju imati utjecaj na njihovu sposobnost za rad, pri čemu medicinsko znanje, poznavanje zdravstvenog sustava kao i organizacijska kultura u radnom kolektivu mogu utjecati na to kako se liječnici prezentiraju kao pacijenti. Kako kvaliteta skrbi za pacijente značajno ovisi o kompetentnosti i djelovanju liječnika, psihološko i tjelesno zdravlje liječnika obiteljske medicine od iznimne je važnosti u pogledu osiguranja optimalnog ishoda pacijentove skrbi. U tom su smislu značajni prevencija, rano prepoznavanje te rana intervencija poremećaja zdravlja liječnika koji uključuju skrb o samome sebi, rezilijenciju i svjesnu praksu, razumijevanje odnosa s pacijentima, primjereno liječenje i rehabilitaciju, uz podršku na radnom mjestu kako bi liječnik održao ili povratio svoje profesionalno funkcioniranje, a pacijentima bila dostupna kvalitetna i sigurna skrb.Achieving and maintaining health is a challenge today and is inextricably linked to maintaining a person's professional performance, including the medical profession. The issue of physician health becomes significant at the moment when a physical, mental health or substance abuse disorder interferes with the ability to perform the medical profession competently and safely, or to provide quality and safe care for patients. The aim of this paper was to provide an overview of contemporary insights into the relationship between family physician's health and quality of health care, with particular reference to preventive activities and possible interventions to preserve physician health. The results of the study show that the health of family physicians can be impaired in all segments as well as in the general population, with a slightly higher incidence of mental health disorders. Physicians may suffer from one or more medical conditions that may or may not have an impact on their ability to work, where medical knowledge, health system knowledge, and organizational culture in the workplace may influence how physicians present themselves as patients. Quality of patient health care is highly dependent upon a competent and functioning physician. The psychological and physical health of a doctor is vital in ensuring optimal patient outcome. In this regard, prevention, early identification and early intervention of physician health disorders, including self-care, resilience and mindful practice, understanding the relationships with patients, appropriate treatment and rehabilitation, with support in the workplace for the physician to maintain or restore his or her professional status are significant. functioning, also available quality and safe care for the patients