On the Spectroscopic Diversity of Type Ia Supernovae

A comparison of the ratio of the depths of two absorption features in the spectra of TypeIa supernovae (SNe Ia) near the time of maximum brightness with the blueshift of the deep red Si II absorption feature 10 days after maximum shows that the spectroscopic diversity of SNe Ia is multi-dimensional. There is a substantial range of blueshifts at a given value of the depth ratio. We also find that the spectra of a sample of SNe Ia obtained a week before maximum brightness can be arranged in a ``blueshift sequence'' that mimics the time evolution of the pre-maximum-light spectra of an individual SN Ia, the well observed SN 1994D. Within the context of current SN Ia explosion models, we suggest that some of the SNe Ia in our sample were delayed-detonations while others were plain deflagrations.Comment: accepted for publication in ApJ

A dimerization model for the concentration dependent photophysical properties of diphenylhexatriene and its phospholipid derivatives. DPHpPC and DPHpPA

We have investigated the reason for the sensitivity of the fluorescence excited-state lifetime of 1,6-diphenyl-1,3,5-hexatriene (DPH) and its phospholipid derivatives, 1-palmitoyl-2-[2-[4-(6-phenyl-trans-1,3,5- hexatrienyl)phenyl]ethyl)carbonyl)-3-sn-phosphatidylcholine (DPHpPC) and 1-palmitoyl-2-[2-[4-(6-phenyl-trans-1,3,5- hexatrienyl)phenyl]ethyl)carbonyl)-3-sn-phosphatidic acid (DPHpPA), to the concentration of these probes in dipalmitoylphosphatidylcholine (DPPC) multilamellar membranes (Barrow, D. A., and B. R. Lentz, 1985. Biophys. J. 48:221-234; Parente, R. A., and B. R. Lentz. 1985. Biochemistry. 24:6178-6185). We have interpreted self-quenching data, excitation and emission spectra, and phase and modulation lifetime data in terms of a model that envisions dimerization of these probes in a membrane bilayer. It is proposed that dimerization alters the symmetry of the DPH excited state so as to allow more rapid decay via the normally symmetry-disallowed route from the 1Ag* state. Global analysis of fluorescence phase shift and modulation ratio data for DPHpPC in terms of the dimerization model provided a good fit of these data as a function of both modulation frequency and probe concentration. Global analysis of a similar set of data for the charged phosphatide DPHpPA predicted that this probe was much less prone to dimerize than was the uncharged DPHpPC. This physically reasonable result provides support for the assumptions made in the development of our model. We conclude that the dimerization model allows rationalization of many of the anomalous photophysical properties of DPH and its derivatives in membranes

Energetics of Vesicle Fusion Intermediates: Comparison of Calculations with Observed Effects of Osmotic and Curvature Stresses

We reported previously the effects of both osmotic and curvature stress on fusion between poly(ethylene glycol)-aggregated vesicles. In this article, we analyze the energetics of fusion of vesicles of different curvature, paying particular attention to the effects of osmotic stress on small, highly curved vesicles of 26 nm diameter, composed of lipids with negative intrinsic curvature. Our calculations show that high positive curvature of the outer monolayer “charges” these vesicles with excess bending energy, which then releases during stalk expansion (increase of the stalk radius, rs) and thus “drives” fusion. Calculations based on the known mechanical properties of lipid assemblies suggest that the free energy of “void” formation as well as membrane-bending free energy dominate the evolution of a stalk to an extended transmembrane contact. The free-energy profile of stalk expansion (free energy versus rs) clearly shows the presence of two metastable intermediates (intermediate 1 at rs ∼0 − 1.0 nm and intermediate 2 at rs ∼2.5 − 3.0 nm). Applying osmotic gradients of ±5 atm, when assuming a fixed trans-bilayer lipid mass distribution, did not significantly change the free-energy profile. However, inclusion in the model of an additional degree of freedom, the ability of lipids to move into and out of the “void”, made the free-energy profile strongly dependent on the osmotic gradient. Vesicle expansion increased the energy barrier between intermediates by ∼4 kT and the absolute value of the barrier by ∼7 kT, whereas compression decreased it by nearly the same extent. Since these calculations, which are based on the stalk hypothesis, correctly predict the effects of both membrane curvature and osmotic stress, they support the stalk hypothesis for the mechanism of membrane fusion and suggest that both forms of stress alter the final stages, rather than the initial step, of the fusion process, as previously suggested

Analysis of the Type IIn Supernova 1998S: Effects of Circumstellar Interaction on Observed Spectra

We present spectral analysis of early observations of the Type IIn supernova 1998S using the general non-local thermodynamic equilibrium atmosphere code \tt PHOENIX}. We model both the underlying supernova spectrum and the overlying circumstellar interaction region and produce spectra in good agreement with observations. The early spectra are well fit by lines produced primarily in the circumstellar region itself, and later spectra are due primarily to the supernova ejecta. Intermediate spectra are affected by both regions. A mass-loss rate of order $\dot M \sim 0.0001-0.001$\msol yr$^{-1}$ is inferred for a wind speed of 100-1000 \kmps. We discuss how future self-consistent models will better clarify the underlying progenitor structure.Comment: to appear in ApJ, 2001, 54

Promoting sustainability in quality improvement: an evaluation of a web-based continuing education program in blood pressure measurement.

BACKGROUND: The accuracy of blood pressure measurement is variable in office-based settings. Even when staff training programs are effective, knowledge and skills decay over time, supporting the need for ongoing staff training. We evaluated whether a web-based continuing education program in blood pressure measurement reinforced knowledge and skills among clinical staff and promoted sustainability of an existing quality improvement program. METHODS: Medical assistants and nurses at six primary care clinics within a health system enrolled in a 30-min online educational program designed to refresh their knowledge of blood pressure measurement. A 20-question pre- and post-intervention survey addressed learners\u27 knowledge and attitudes. Direct observation of blood pressure measurement technique before and after the intervention was performed. Differences in responses to pre- and post-module knowledge and attitudes questions and in observation data were analyzed using chi-square tests and simple logistic regression. RESULTS: All 88 clinical staff members participated in the program and completed the evaluation survey. Participants answered 80.6% of questions correctly before the module and 93.4% afterwards (p \u3c 0.01). Scores improved significantly among staff from all job types. Licensed practical nurses and staff who had been in their current job at least a year were more likely to answer questions correctly than registered nurses and those in their current job less than a year. Attitudes toward correct blood pressure measurement were high at baseline and did not improve significantly. Prior to the intervention, staff adhered to 9 of 18 elements of the recommended technique during at least 90% of observations. Following the program, staff was more likely to explain the protocol, provide a rest period, measure an average blood pressure, and record the average blood pressure, but less likely to measure blood pressure with the arm at heart level and use the right arm. CONCLUSIONS: We designed, implemented, and evaluated a web-based educational program to improve knowledge, skills, and attitudes in blood pressure measurement and use of an automated device among nurses and medical assistants in ambulatory care. The program reinforced knowledge related to recommended blood pressure measurement technique. TRIAL REGISTRATION: Retrospectively registered with ClincalTrials.gov on March 22, 2012; registration number NCT01566864

Evidence for Asphericity in the Type IIn Supernova 1998S

We present optical spectropolarimetry obtained at the Keck-II 10-m telescope on 1998 March 7 UT along with total flux spectra spanning the first 494 days after discovery (1998 March 2 UT) of the peculiar type IIn supernova (SN) 1998S. The SN is found to exhibit a high degree of linear polarization, implying significant asphericity for its continuum-scattering environment. Prior to removal of the interstellar polarization, the polarization spectrum is characterized by a flat continuum (at p ~ 2%) with distinct changes in polarization associated with both the broad (FWZI >= 20,000 km/s) and narrow (unresolved, FWHM < 300 km/s) line emission seen in the total flux spectrum. When analyzed in terms of a polarized continuum with unpolarized broad-line recombination emission, an intrinsic continuum polarization of p ~ 3% results (the highest yet found for a SN), suggesting a global asphericity of >= 45% from the oblate, electron-scattering dominated models of Hoflich (1991). The smooth, blue continuum evident at early times is shown to be inconsistent with a reddened, single-temperature blackbody, instead having a color temperature that increases with decreasing wavelength. Broad emission-line profiles with distinct blue and red peaks are seen in the total flux spectra at later times, perhaps suggesting a disk-like or ring-like morphology for the dense (n_e ~ 10^7 cm^{-3}) circumstellar medium. Implications of the circumstellar scattering environment for the spectropolarimetry are discussed, as are the effects of uncertain removal of interstellar polarization.Comment: 25 pages + 2 tables + 14 figures, Submitted to The Astrophysical Journa

Quantitative analysis of cell types during growth and morphogenesis in Hydra

Tissue maceration was used to determine the absolute number and the distribution of cell types in Hydra. It was shown that the total number of cells per animal as well as the distribution of cells vary depending on temperature, feeding conditions, and state of growth. During head and foot regeneration and during budding the first detectable change in the cell distribution is an increase in the number of nerve cells at the site of morphogenesis. These results and the finding that nerve cells are most concentrated in the head region, diminishing in density down the body column, are discussed in relation to tissue polarity

Statistical Similarities Between WSA‐ENLIL+Cone Model and MAVEN in Situ Observations From November 2014 to March 2016

Normal solar wind flows and intense solar transient events interact directly with the upper Martian atmosphere due to the absence of an intrinsic global planetary magnetic field. Since the launch of the Mars Atmosphere and Volatile EvolutioN (MAVEN) mission, there are now new means to directly observe solar wind parameters at the planet’s orbital location for limited time spans. Due to MAVEN’s highly elliptical orbit, in situ measurements cannot be taken while MAVEN is inside Mars’ magnetosheath. To model solar wind conditions during these atmospheric and magnetospheric passages, this research project utilized the solar wind forecasting capabilities of the WSA‐ENLIL+Cone model. The model was used to simulate solar wind parameters that included magnetic field magnitude, plasma particle density, dynamic pressure, proton temperature, and velocity during a four Carrington rotation‐long segment. An additional simulation that lasted 18 Carrington rotations was then conducted. The precision of each simulation was examined for intervals when MAVEN was in the upstream solar wind, that is, with no exospheric or magnetospheric phenomena altering in situ measurements. It was determined that generalized, extensive simulations have comparable prediction capabilities as shorter, more comprehensive simulations. Generally, this study aimed to quantify the loss of detail in long‐term simulations and to determine if extended simulations can provide accurate, continuous upstream solar wind conditions when there is a lack of in situ measurements.Plain Language SummaryIf we ever have a manned mission to Mars, one of the numerous concerns would be space weather conditions and their effects on spacecraft in flight. One particular element of space weather that we like to focus on is solar wind: plasma that is continuously emitted from the Sun. Solar wind can effect communication between Earth and spacecraft, GPS services, and other vital elements of space travel. We therefore want a good understanding of space weather and want to forecast conditions before ever traveling there. Currently, there are not always means to directly measure solar wind, so we rely on numerical models. In this study, we used the model called WSA‐ENLIL+Cone to compare its solar wind measurements and one of our spacecraft orbiting Mars to see how well it did and to see if we can rely on it for solar wind forecasts. As it turns out, the model can be used for forecasting baseline values of different solar wind parameters, for example, temperature, even with limited information. We show in this study that the WSA‐ENLIL+Cone model allows us to forecast solar wind conditions and helps us to understand what is going on at that seemingly barren planet.Key PointsGeneralized, extensive WEC model simulations provide analogous confidence levels and results as detailed, relatively short simulationsWSA‐ENLIL+Cone model succeeds at predicting fast solar wind radial velocityPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142959/1/swe20547.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142959/2/swe20547_am.pd

Heat and salt balances over the New England continental shelf, August 1996 to June 1997

Heat and salt balances over the New England shelf are examined using 10 month time series of currents, temperature, and salinity from a four element moored array and surface heat and freshwater fluxes from a meteorological buoy. A principal result is closure of the heat budget to 10 W m−2. The seasonal variation in depth‐average temperature, from 14°C in September to 5°C in March, was primarily due to the seasonal variation in surface heat flux and a heat loss in winter caused by along‐shelf advection of colder water from the northeast. Conductivity sensor drifts precluded closing the salt balance on time scales of months or longer. For time scales of days to weeks, depth‐average temperature and salinity variability were primarily due to advection. Advective heat and salt flux divergences were strongest and most complex in winter, when there were large cross‐shelf temperature and salinity gradients at the site due to the shelf‐slope front that separates cooler, fresher shelf water from warmer, saltier slope water. Onshore flow of warm, salty slope water near the bottom and offshore flow of cooler, fresher shelf water due to persistent eastward (upwelling‐favorable) winds caused a temperature increase of nearly 3°C and a salinity increase of 0.8 in winter. Along‐shelf barotropic tidal currents caused a temperature decrease of 1.5°C and a salinity decrease of 0.7. Wave‐driven Stokes drift caused a temperature increase of 0.5°C and a salinity increase of 0.4 from mid December to January when there were large waves and large near‐surface cross‐shelf temperature and salinity gradients.Keywords: New England continental shelf, Heat and salt balancesKeywords: New England continental shelf, Heat and salt balance