Reconstructing past atmospheric circulation changes using oxygen isotopes in lake sediments from Sweden

Here we use lake sediment studies from Sweden to illustrate how Holocene-aged oxygen isotope records from lakes located in different hydrological settings, can provide information about climate change. In particular changes in precipitation, atmospheric circulation and water balance. We highlight the importance of understanding the present lake hydrology, and the relationship between climate variables and the oxygen isotopic composition of precipitation (18Op) and lake waters (18Olakewater) for interpretation of the oxygen isotopic record from the sediments (18O). Both precipitation reconstructions from northern Sweden and water balance reconstructions from south and central Sweden show that the atmospheric circulation changed from zonal to a more meridional airflow over the Holocene. Superimposed on this Holocene trend are δ18Op minima resembling intervals of the negative phase of the North Atlantic Oscillation (NAO), thus suggesting that the climate of Northern Europe is strongly influenced by atmospheric and oceanic circulation changes over the North Atlantic

Modeling phase behavior for quantifying micro-pervaporation experiments

We present a theoretical model for the evolution of mixture concentrations in a micro-pervaporation device, similar to those recently presented experimentally. The described device makes use of the pervaporation of water through a thin PDMS membrane to build up a solute concentration profile inside a long microfluidic channel. We simplify the evolution of this profile in binary mixtures to a one-dimensional model which comprises two concentration-dependent coefficients. The model then provides a link between directly accessible experimental observations, such as the widths of dense phases or their growth velocity, and the underlying chemical potentials and phenomenological coefficients. It shall thus be useful for quantifying the thermodynamic and dynamic properties of dilute and dense binary mixtures.Comment: to be published in EPJ-

Femoral atherosclerosis in an older British population: prevalence and risk factors

Most estimates of the prevalence of peripheral atherosclerosis have been based on intermittent claudication or lower limb blood flow. The aim of this study was therefore to determine the prevalence of underlying femoral plaque, and to determine its association with other cardiovascular disease and risk factors. Presence of plaque was identified using ultrasound in a random sample of men (n = 417) and women (n = 367) aged 56-77 years. Coexistent cardiovascular disease, exercise and smoking were determined by questionnaire, blood pressure was recorded, and serum cholesterol and plasma fibrinogen were determined. Of the 784 subjects that were scanned, 502 (64%) demonstrated atherosclerotic plaque. Disease prevalence increased significantly with age (P lt 0.0001), and was more common in men (67.1 vs. 59.4%, P lt 0.05). Subjects with femoral plaque had a significantly greater odds of previous ischaemic heart disease (OR 2.2, 95% CI 1.3, 3.7) and angina (OR 1.7, 95% CI 1.03, 2.7), but not of stroke or leg pain on exercise. Current and ex-smoking, raised serum total cholesterol and plasma fibrinogen levels, but not blood pressure, were associated with an increased risk of femoral plaque, independent of age and sex. Frequent exercise and a high HDL cholesterol were significantly associated with lower risk. In conclusion, therefore, atherosclerotic disease of the femoral artery affects almost two-thirds of the population in late middle age. It is associated with an increased prevalence of ischaemic heart disease and angina, but whether detecting at risk individuals using ultrasound offers advantages over simpler and less expensive risk factor scoring requires evaluation in trials