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Genetic and physiological factors affecting repair and mutagenesis in yeast
Current views of DNA repair and mutagenesis in the yeast Saccharomyces cerevisiae are discussed in the light of recent data and with emphasis on the isolation and characterization of genetically well-defined mutations that affect DNA metabolism in general (including replication and recombination). Various pathways of repair are described, particularly in relation to their imvolvement in mutagenic mechanisms. In addition to genetic control, certain physiological factors such as cell age, DNA replication, and the regulatory state of the mating-type locus are shown to also play a role in repair and mutagenesis
Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics
The effects of three rad genes on UV induced mutation rates in haploid and diploid Saccharomyces cells
Coordination of DNA damage tolerance mechanisms with cell cycle progression in fission yeast
a/alpha-specific effect on the mms3 mutation on ultraviolet mutagenesis in Saccharomyces cerevisiae
DNA Polymerases and Combine to Bypass O2[4-(3-Pyridyl)-4-oxobutyl]thymine a DNA Adduct Formed from Tobacco Carcinogens
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