Le sentiment de présence au monde, le sentiment de présence à la peinture

Ce texte est l'accompagnement réflexif du corpus d'oeuvres Les assises, un ensemble de huit tableaux, réalisé lors de mes deux années à la maitrise et présenté à la Galerie des arts visuels du 25 au 30 août 2009. Il décortique le processus élaboré pour ce projet en peinture, dont la principale problématique touche à la nature de l'expérience de représentation, en permettant d'expliciter deux phases de la création de l'oeuvre qui demeurent inaccessibles à l'exposition. La première phase concerne la création d'un matériel photographique saisissant dans un espace neutre différentes étapes d'une mise en scène où j'entre en relation avec certains objets dont principalement des chaises. Afin de constituer une expérience originale, je vise à réinventer la relation physique avec ces objets en tentant d'éliminer les automatismes liés à la fonctionnalité de ceux-ci dans le cadre quotidien. Cette étape est nourrie par la recherche d'une intensité de la présence personnelle dans le champ spatio-temporel de l'expérience qui prend la forme d'une « performance » dite privée, captée par une caméra vidéo. La deuxième phase se situe dans le champ du « faire » de la peinture. J'élabore les tableaux à partir des documents vidéo ou photographiques produits lors des événements performatifs. Les oeuvres prennent forme par des étapes d'actions connectées tout autant à l'expérience passée qu'à l'apparition graduelle de la représentation. Double état de conscience qui puise dans la mémoire affective tout en développant une traduction picturale à partir des choix de couleurs, et des gestuelles d'application. Aussi, au cours de ce mémoire, je m'intéresse au point de vue du regardeur, j'expose certaines notes d'ateliers et présente les oeuvres

What More Do Bodies Know? Moving with the Gendered Affects of Place

This article focuses on what bodies know yet which cannot be expressed verbally. It starts with a problem encountered during conventional interviewing in an ex-mining community in south Wales when some teen girls struggled to speak. This led us to focus on the body, corporeality and movement in improvisational dance workshops. By slowing down and speeding up video footage from the workshops, we notice movement patterns and speculate about how traces of gendered body-movement practices developed within mining communities over time become actualised in girls’ habitual movement repertoires. Inspired by the works of Gilles Deleuze, Felix Guattari and Erin Manning, a series of cameos (room dancing; the hold; the wiggle; the leap and dance of the not-yet) are presented. We speculate about relations between the actual movements we could see, the in-act infused with the history of place and the virtual potential of what movement

A value-based comparison of the management of ambulatory respiratory diseases in walk-in clinics, primary care practices, and emergency departments : protocol for a multicenter prospective cohort study

Background: In Canada, 30%-60% of patients presenting to emergency departments are ambulatory. This category has been labeled as a source of emergency department overuse. Acting on the presumption that primary care practices and walk-in clinics offer equivalent care at a lower cost, governments have invested massively in improving access to these alternative settings in the hope that patients would present there instead when possible, thereby reducing the load on emergency departments. Data in support of this approach remain scarce and equivocal. Objective: The aim of this study is to compare the value of care received in emergency departments, walk-in clinics, and primary care practices by ambulatory patients with upper respiratory tract infection, sinusitis, otitis media, tonsillitis, pharyngitis, bronchitis, influenza-like illness, pneumonia, acute asthma, or acute exacerbation of chronic obstructive pulmonary disease. Methods: A multicenter prospective cohort study will be performed in Ontario and Québec. In phase 1, a time-driven activity-based costing method will be applied at each of the 15 study sites. This method uses time as a cost driver to allocate direct costs (eg, medication), consumable expenditures (eg, needles), overhead costs (eg, building maintenance), and physician charges to patient care. Thus, the cost of a care episode will be proportional to the time spent receiving the care. At the end of this phase, a list of care process costs will be generated and used to calculate the cost of each consultation during phase 2, in which a prospective cohort of patients will be monitored to compare the care received in each setting. Patients aged 18 years and older, ambulatory throughout the care episode, and discharged to home with one of the aforementioned targeted diagnoses will be considered. The estimated sample size is 1485 patients. The 3 types of care settings will be compared on the basis of primary outcomes in terms of the proportion of return visits to any site 3 and 7 days after the initial visit and the mean cost of care. The secondary outcomes measured will include scores on patient-reported outcome and experience measures and mean costs borne wholly by patients. We will use multilevel generalized linear models to compare the care settings and an overlap weights approach to adjust for confounding factors related to age, sex, gender, ethnicity, comorbidities, registration with a family physician, socioeconomic status, and severity of illness. Results: Phase 1 will begin in 2021 and phase 2, in 2023. The results will be available in 2025. Conclusions: The end point of our program will be for deciders, patients, and care providers to be able to determine the most appropriate care setting for the management of ambulatory emergency respiratory conditions, based on the quality and cost of care associated with each alternative

Researching COVID to Enhance Recovery (RECOVER) Adult Study Protocol: Rationale, Objectives, and Design

IMPORTANCE: SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are ill-defined. The objectives of the Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC in Adults (RECOVER-Adult) are to: (1) characterize PASC prevalence; (2) characterize the symptoms, organ dysfunction, natural history, and distinct phenotypes of PASC; (3) identify demographic, social and clinical risk factors for PASC onset and recovery; and (4) define the biological mechanisms underlying PASC pathogenesis. METHODS: RECOVER-Adult is a combined prospective/retrospective cohort currently planned to enroll 14,880 adults aged ≥18 years. Eligible participants either must meet WHO criteria for suspected, probable, or confirmed infection; or must have evidence of no prior infection. Recruitment occurs at 86 sites in 33 U.S. states, Washington, DC and Puerto Rico, via facility- and community-based outreach. Participants complete quarterly questionnaires about symptoms, social determinants, vaccination status, and interim SARS-CoV-2 infections. In addition, participants contribute biospecimens and undergo physical and laboratory examinations at approximately 0, 90 and 180 days from infection or negative test date, and yearly thereafter. Some participants undergo additional testing based on specific criteria or random sampling. Patient representatives provide input on all study processes. The primary study outcome is onset of PASC, measured by signs and symptoms. A paradigm for identifying PASC cases will be defined and updated using supervised and unsupervised learning approaches with cross-validation. Logistic regression and proportional hazards regression will be conducted to investigate associations between risk factors, onset, and resolution of PASC symptoms. DISCUSSION: RECOVER-Adult is the first national, prospective, longitudinal cohort of PASC among US adults. Results of this study are intended to inform public health, spur clinical trials, and expand treatment options

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

Research Priorities for Childhood Apraxia of Speech: A Long View

This article introduces the Journal of Speech, Language, and Hearing Research Special Issue: Selected Papers From the 2022 Apraxia Kids Research Symposium. The field of childhood apraxia of speech (CAS) has developed significantly in the past 15 years, with key improvements in understanding of basic biology including genetics, neuroscience, and computational modelling; development of diagnostic tools and methods; diversity of evidence-based interventions with increasingly rigorous experimental designs; and understanding of impacts beyond impairment-level measures. Papers in this special issue not only review and synthesize the some of the substantial progress to date but also present novel findings addressing critical research gaps and adding to the overall body of knowledge. A second aim of this prologue is to report the current research needs in CAS, which arose from symposium discussions involving researchers, clinicians, and Apraxia Kids community members (including parents of children with CAS). Four primary areas of need emerged from discussions at the symposium. These were: (a) What questions should we ask? (b) Who should be in the research? (c) How do we conduct the research? and (d) How do we move from research to practice? Across themes, symposium attendees emphasized the need for CAS research to better account for the diversity of people with CAS and improve the timeliness of implementation of high-level evidence-based practice across the lifespan. It is our goal that the articles and prologue discussion in this special issue provide an appreciation of advancements in CAS research and an updated view of the most pressing needs for future research

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P &lt; 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

Les pharmacopsychoses au cannabis (génèse, développement et limites du concept à travers une revue de la littérature)

Le haschisch herbe de folie et de rêve selon Brotteaux, est une des plantes les plus anciennement connues et utilisées par l'homme. La psychose cannabique, en particulier, pourtant admise dans les pays d'Afrique du Nord où la consommation de cannabis est importante, fait l'objet de nombreuses études épidémiologiques à travers le monde qui prouvent ou au contraire réfutent son existence. L'augmentation et la banalisation de la consommation de cannabis chez les jeunes de moins de 18 ans, âge de fragilité psychique et d'émergence de schizophrénie, réactivent le débat suivant : Le cannabis peut-il déclencher un trouble psychotique voire une schizophrénie, ou est-il un facteur de vulnérabilité à l'émergence ou à la révélation d'une psychose sous-jacente ? Au cours de cette revue de la littérature, nous avons pu constater que l'innocuité du cannabis ne peut être établie et que son effet psychodysleptique n'est pas remis en cause. Cette substance peut produire des effets psychologiques (cognitifs et psychomoteurs) ainsi qu'une dépendance psychique. Concernant les troubles psychotiques induits par le cannabis à travers ces publications abondantes et contradictoires, nous avons mis en évidence le polymorphisme sémiologique de la psychose cannabique. Outre l'ivresse cannabique, le cannabis peut déterminer une psychose toxique aiguë ainsi qu'une psychose d'allure fonctionnelle de plus longue durée. En cas de consommation ancienne et prolongée, le cannabis pourrait déterminer une psychose chronique, difficile à distinguer d'une schizophrénie. Le syndrome amotivationnel, lié au cannabis, représenterait une psychose chronique et s'apparenterait à une psychose hébéphrénique de type déficitaire. La comorbidité entre schizophrénie et abus de cannabis est très fréquente, enrichit la réflexion sur l'étiopathogénie des schizophrénies et conduit à trois hypothèses pour expliquer le lien entre ces deux troubles : la consommation de cannabis comme automédication ; le cannabis comme facteur de vulnérabilité à la schizophrénie ; l'existence de mécanismes neurobiologiques et génétiques communs.ROUEN-BU Médecine-Pharmacie (765402102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Counter-Electrojet Occurrence as Observed From C/NOFS Satellite and Ground-Based Magnetometer Data Over the African and American Sectors

An analysis of the counter-electrojet occurrence (CEJ) during 2008-2014 is presented for the African and American sectors based on local daytime (0700-1700 LT) observations from the Communications and Navigation Outage Forecasting System (C/NOFS) vertical ion plasma drift (equivalent to vertical Eà B at an altitude of about 400 km) and ground-based magnetometers. Using quiet time (Kp- 3) data, differences and/or similarities between the two data sets with reference to local time and seasonal dependence are established. For the first time, it is shown that C/NOFS satellite data are consistent with magnetometer observations in identifying CEJ occurrences during all seasons. However, C/NOFS satellite data show higher CEJ occurrence rate for almost all seasons. With respect to local time, C/NOFS satellite observes more CEJ events than magnetometer observations by average of about 20% and 40% over the American and African sectors, respectively, despite both data sets showing similar trends in CEJ identification. Therefore, when a space weather event occurs, it is important to first establish the original variability nature and/or magnitude of the eastward electric field in equatorial regions before attributing the resulting changes to solar wind-magnetosphere and ionosphere coupling processes since CEJ events can be present even during quiet conditions.Key PointsA statistical trend of CEJ events using C/NOFS satellite vertical ion plasma drift and magnetometer observations has been establishedBoth C/NOFS satellite and magnetometer data show higher CEJ occurrence rate over the African sector than the American sectorC/NOFS satellite data exhibit more CEJ events than magnetometer data by average of 20% (40%) over the American (African) sectorPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151259/1/swe20897.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151259/2/swe20897_am.pd