Role of Iron in the Marquesas Island Mass Effect

A remarkable chlorophyll‐a concentration (Chl, a proxy of phytoplankton biomass) plume can be noticed on remotely sensed ocean color observations at the boundary separating the equatorial mesotrophic from the subtropical oligotrophic waters in the central South Pacific Ocean. This prominent biological feature is known as the island mass effect of the Marquesas archipelago. Waters surrounding these islands present high macronutrient concentrations but an iron depletion. In this study, the origin of Chl enhancement is investigated using a modeling approach. Four simulations based on identical physical and biogeochemical forcings but with different iron sources are conducted and analyzed. Only simulations considering an iron input from the island sediments present similar patterns (despite being too weak) of vertical and horizontal Chl distributions as compared to biogeochemical‐Argo profiling float and satellite observations. In addition, simulations with no other iron input than the boundary forcings reveal the relative importance of remote processes in modulating the seasonal pattern of Chl around the archipelago through horizontal advection of nutrient‐rich waters from the equator toward the archipelago and vertical mixing uplifting deep nutrient‐rich waters toward the upper lit layer

Characteristics of Patients with Infective Endocarditis and No Underlying Cardiac Conditions.

International audienceBACKGROUND: Infective endocarditis (IE) typically occurs in patients with underlying cardiac conditions (UCC). Little is known about IE in patients without UCC. We aimed to describe the clinical, microbiological and imaging characteristics, management, and in-hospital mortality of IE patients without UCC. METHODS: We analysed the data of patients with definite IE included in an observatory between 1st January 2009 and 31st December 2019. We described patients without UCC compared to those with UCC. RESULTS: Of 1502 IE patients, 475 (31.6%) had no UCC. They were younger (median 64.0 [19.0-101.0] vs. 70.0 [18.0-104.0] years, p\,<\,.001), more often on chronic haemodialysis (5.5% vs. 2.7%, p\,=\,.008), and had more often malignancy (22.5% vs. 17.3%, p\,=\,.017), immune deficiency (10.3% vs. 6.4%, p\,=\,.008), and an indwelling central venous line (14.5% vs. 7.0%, p\,<\,.001). They more often developed cerebral complications (34.7% vs. 27.5%, p\,=\,.004) and extracerebral embolism (48.6% vs. 36.1%, p\,<\,.001). Causative microorganisms were less often coagulase negative staphylococci (5.9% vs. 10.8%, p\,=\,.002) or enterococci (10.3% vs. 15.0%, p\,=\,.014) and more often group D streptococci (14.1% vs. 10.0%, p\,=\,.020). Vegetations were more common (92.8% vs. 77.0%, p\,<\,.001) and larger (14.0 [1.0-87.0], vs. 12.0 [0.5-60.0] mm, p\,=\,.002). They had more valve perforation or valve regurgitation (67.4% vs. 53.0%, p\,<\,.001) and underwent valve surgery more often (53.5% vs. 36.3%, p\,<\,.001). In-hospital mortality did not significantly differ between groups. CONCLUSION: Patients with IE and no UCC were younger than those with UCC, had specific comorbidities and portals of entry, and a more severe disease course

The lacertus fibrosus of the biceps brachii muscle: an anatomical study.

The lacertus fibrosus (LF) is involved in various surgical procedures. However, the anatomy, morphometry, topography and biomechanical involvements of LF are not clear. The purpose of this study was to determine the anatomical and morphometric variations of LF, and to correlate this with anthropometric and morphometric measurements of the upper limb. Furthermore, the presence or absence of a deep layer of LF was verified using forearm cross-sections and dissections.JOURNAL ARTICLESCOPUS: ar.jinfo:eu-repo/semantics/publishe

Le Chemin aux Errants, zone C (Haute-Normandie, Eure, Val-de-Reuil): Rapport de fouille 2015

International audienceLe site du « Chemin aux Errants » se trouve en fond de vallée de l’Eure, à une centaine de mètres du cours actuel de la rivière, en rive droite, sur un dôme naturel de grave. Intervenue entre 2011 et 2012, dans le cadre de l’extension d’une carrière de granulats de la société CEMEX, la fouille s’est effectuée sur une superficie d’un peu moins de 8 ha. Elle a fourni de nombreux éléments d’informations, allant du premier âge du Fer jusqu’au Moyen Âge, de manière plus ou moins discontinue. Ces données participent activement à la riche documentation de cette partie de la région, notamment pour ce que l’on appelle la boucle du Vaudreuil durant la période antique et surtout, alto-médiévale. Ce secteur de la confluence entre Seine et Eure révèle en effet une multitude de sites, néanmoins pour la plupart insuffisamment documentés, en raison des contraintes d’emprises

A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency

International audiencePURPOSE: Patients with primary immunodeficiency (PID) are at risk of serious complications. However, data on the incidence and causes of emergency hospital admissions are scarce. The primary objective of the present study was to describe emergency hospital admissions among patients with PID, with a view to identifying "at-risk" patient profiles.METHODS: We performed a prospective observational 12-month multicenter study in France via the CEREDIH network of regional PID reference centers from November 2010 to October 2011. All patients with PIDs requiring emergency hospital admission were included.RESULTS: A total of 200 admissions concerned 137 patients (73 adults and 64 children, 53% of whom had antibody deficiencies). Thirty admissions were reported for 16 hematopoietic stem cell transplantation recipients. When considering the 170 admissions of non-transplant patients, 149 (85%) were related to acute infections (respiratory tract infections and gastrointestinal tract infections in 72 (36%) and 34 (17%) of cases, respectively). Seventy-seven percent of the admissions occurred during winter or spring (December to May). The in-hospital mortality rate was 8.8% (12 patients); death was related to a severe infection in 11 cases (8%) and Epstein-Barr virus-induced lymphoma in 1 case. Patients with a central venous catheter (n = 19, 13.9%) were significantly more hospitalized for an infection (94.7%) than for a non-infectious reason (5.3%) (p = 0.04).CONCLUSION: Our data showed that the annual incidence of emergency hospital admission among patients with PID is 3.4%. The leading cause of emergency hospital admission was an acute infection, and having a central venous catheter was associated with a significantly greater risk of admission for an infectious episode

A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency

International audiencePURPOSE: Patients with primary immunodeficiency (PID) are at risk of serious complications. However, data on the incidence and causes of emergency hospital admissions are scarce. The primary objective of the present study was to describe emergency hospital admissions among patients with PID, with a view to identifying "at-risk" patient profiles.METHODS: We performed a prospective observational 12-month multicenter study in France via the CEREDIH network of regional PID reference centers from November 2010 to October 2011. All patients with PIDs requiring emergency hospital admission were included.RESULTS: A total of 200 admissions concerned 137 patients (73 adults and 64 children, 53% of whom had antibody deficiencies). Thirty admissions were reported for 16 hematopoietic stem cell transplantation recipients. When considering the 170 admissions of non-transplant patients, 149 (85%) were related to acute infections (respiratory tract infections and gastrointestinal tract infections in 72 (36%) and 34 (17%) of cases, respectively). Seventy-seven percent of the admissions occurred during winter or spring (December to May). The in-hospital mortality rate was 8.8% (12 patients); death was related to a severe infection in 11 cases (8%) and Epstein-Barr virus-induced lymphoma in 1 case. Patients with a central venous catheter (n = 19, 13.9%) were significantly more hospitalized for an infection (94.7%) than for a non-infectious reason (5.3%) (p = 0.04).CONCLUSION: Our data showed that the annual incidence of emergency hospital admission among patients with PID is 3.4%. The leading cause of emergency hospital admission was an acute infection, and having a central venous catheter was associated with a significantly greater risk of admission for an infectious episode

Outcome after failure of allogeneic hematopoietic stem cell transplantation in children with acute leukemia: a study by the société Francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC)

International audienc

Multi-strange baryon production in pp collisions at √s=7 TeV with ALICE

A measurement of the multi-strange Ξ− and Ω− baryons and their antiparticles by the ALICE experiment at the CERN Large Hadron Collider (LHC) is presented for inelastic proton–proton collisions at a centre-of-mass energy of 7 TeV. The transverse momentum (pT) distributions were studied at mid-rapidity (|y|6.0 GeV/c. We also illustrate the difference between the experimental data and model by comparing the corresponding ratios of (Ω−+Ω¯+)/(Ξ−+Ξ¯+) as a function of transverse mass

Heavy flavour decay muon production at forward rapidity in proton–proton collisions at √s=7 TeV

The production of muons from heavy flavour decays is measured at forward rapidity in proton–proton collisions at √s=7 TeV collected with the ALICE experiment at the LHC. The analysis is carried out on a data sample corresponding to an integrated luminosity Lint=16.5 nb−1. The transverse momentum and rapidity differential production cross sections of muons from heavy flavour decays are measured in the rapidity range 2.5<y<4, over the transverse momentum range 2<pt<12 GeV/c. The results are compared to predictions based on perturbative QCD calculations