Energy Flow in the Region 2 Field‐Aligned Current Region Under Quasi‐steady Convection

We investigated energy flow in the inner magnetosphere on the basis of the results obtained by a global magnetohydrodynamic simulation. When the magnetosphere is exposed to a southward interplanetary magnetic field, the magnetosphere undergoes quasi-steady convection. Downward (earthward) Poynting flux is found in the polar cap, which is consistent with previous observations. However, Poynting flux appears to be upward (antiearthward) in the equatorward region of the auroral oval. The Region 2 field-aligned current (FAC) is embedded in the upward Poynting flux region. The upward Poynting flux is closely associated with space charge deposited by the ionospheric Hall current under inhomogeneous ionospheric conductivity. The space charge gives rise to shear flow of plasma, which is transmitted upward to the magnetosphere. The shear flow generates additional Region 2 FAC, at least, in the low-altitude magnetosphere. Spatial distribution of the Region 2 FAC appears to depend on altitude, suggesting the significant influence of the ionosphere in the Region 2 FAC region. We traced integral curves of Poynting flux (S curves) backward from a magnetic field line in the Region 2 FAC region and found that the S curves originate either in the solar wind and in the earthward-most boundary of the simulation. These simulation results suggest that the ionosphere participates in the generation of the Region 2 FAC, and the ionosphere is a mediator to feed energy to the inner magnetosphere under the quasi-steady convection

The basic solar wind speed distribution and its sunspot cycle variations

In this paper, it is suggested that the latitudinal solar wind speed observed by the Ulysses spacecraft during the lowest solar activity (when both the ecliptic and magnetic equators coincide) may be identified as the basic speed distribution throughout the solar cycle. We demonstrate this suggestion by rotating this particular Ulysses distribution counterclockwise up to 70° in accordance with the rotation of the equivalent dipole axis during active periods of the cycle. The corresponding magnetic equator in the Carrington map latitude-longitude (27 days) becomes quasi-sinusoidal with respect to the ecliptic equator. The quasi-sinusoidal magnetic equator on the Carrington map and its modification associated with the degree of sunspot activities can explain the two high speed peaks (750–800 km/s) and the two lowest speed (350 km/s) during 27-day solar rotation periods, most clearly recognizable after the sunspot peak period. Thus, it may be not necessary to consider coronal holes or open regions as the source of high speed streams. In fact, this particular (lowest solar activity) Ulysses distribution may represent the speed distribution pattern by the basic generation process of the solar wind itself

Gamma Ray and Radon Anomalies in Northern Taiwan as a Possible Preearthquake Indicator around the Plate Boundary

Taiwan is tectonically situated in an oblique collision zone between the Philippine Sea Plate (PSP) and the Eurasian Plate (EP). Continuous observations of gamma rays at the Yangmingshan (YMSG) station and soil radon at the Tapingti (TPT) station were recorded in the volcanic area and around a major fault zone, respectively, in Taiwan for seismic studies. A number of anomalous high gamma ray counts and radon concentrations at certain times were found. It is noted that significant increases of soil radon concentrations were observed and followed by the increase in gamma rays a few days to a few weeks before earthquakes that occurred in northeastern Taiwan. Earthquakes such as these are usually related to the subduction of the PSP beneath the EP to the north along the subduction zone in northern Taiwan (e.g., ML = 6 4, April 20, 2015). It is suggested that the preseismic activity may be associated with slow geodynamic processes at the subduction interface, leading to the PSP movement triggering radon enhancements at the TPT station. Furthermore, the further movement of the PSP might be blocked by the EP, with the accumulated elastic stress resulting in the increase of gamma rays due to the increase in porosity and fractures below the YMSG station. The continuous monitoring of the multiple parameters can improve the understanding of the relationship between the observed radon and gamma ray variations and the regional crustal stress/strain in north and northeastern Taiwan

Preseismic anomalies in soil-gas radon associated with 2016 M 6.6 Meinong earthquake, Southern Taiwan

Taiwan is tectonically situated in a terrain resulting from the oblique collision between the Philippine Sea plate and the continental margin of the Asiatic plate, with a continuous stress causing the density of strong-moderate earthquakes and regional active faults. The continuous time series of soil radon for earthquake studies have been recorded and some significant variations associated with strong earthquakes have been observed. Earthquake prediction is not still operative but these correlations should be added to the literature about seismo-geochemical transients associated to strong earthquakes. Rain-pore pressure related variations, crustal weakness at the studied faults system is consistent with the simultaneous radon anomalies observed. During the observations, a significant increase of soil radon concentrations was observed at Chunglun-T1 (CL-T1), Hsinhua (HH), Pingtung (PT), and Chihshan (CS) stations approximately two weeks before the Meinong earthquake (ML = 6.6, 6 February 2016) in Southern Taiwan. The precursory changes in a multi-stations array may reflect the preparation stage of a large earthquake. Precursory signals are observed simultaneously and it can apply certain algorithms the approximate location and magnitude of the impending earthquake

Recent work on sprite spectrum in Taiwan

campaigns in Taiwan. We first introduce two types of spectroimagers, the slit and slitless types, and discuss their advantages and shortcomings. Next we explore the instrument development and procedures undertaken for this study. In 2006, a slit spectroimager was installed for a sprite campaign and on 15 August of that year, two sprite spectra were recorded using the slit spectroimager along with seven sprites, one halo, one ELVES emission and two jets. By the end of 2015, a slitless spectroimager had been successfully constructed and was ready to conduct additional investigations. On 7 May 2016, a sprite spectrum was recorded using the slitless spectroimager. Following an examination of the calibrations (comprising detection region field of view, wavelength calibration, and response curve), data analysis, and additional calibrations (comprising elevation and azimuthal angles, atmospheric transmittance, and theoretical wavelength calculations) performed in this study, we present the results from our observed sprite spectra using the slit and slitless spectroimagers

Women with endometriosis have higher comorbidities: Analysis of domestic data in Taiwan

AbstractEndometriosis, defined by the presence of viable extrauterine endometrial glands and stroma, can grow or bleed cyclically, and possesses characteristics including a destructive, invasive, and metastatic nature. Since endometriosis may result in pelvic inflammation, adhesion, chronic pain, and infertility, and can progress to biologically malignant tumors, it is a long-term major health issue in women of reproductive age. In this review, we analyze the Taiwan domestic research addressing associations between endometriosis and other diseases. Concerning malignant tumors, we identified four studies on the links between endometriosis and ovarian cancer, one on breast cancer, two on endometrial cancer, one on colorectal cancer, and one on other malignancies, as well as one on associations between endometriosis and irritable bowel syndrome, one on links with migraine headache, three on links with pelvic inflammatory diseases, four on links with infertility, four on links with obesity, four on links with chronic liver disease, four on links with rheumatoid arthritis, four on links with chronic renal disease, five on links with diabetes mellitus, and five on links with cardiovascular diseases (hypertension, hyperlipidemia, etc.). The data available to date support that women with endometriosis might be at risk of some chronic illnesses and certain malignancies, although we consider the evidence for some comorbidities to be of low quality, for example, the association between colon cancer and adenomyosis/endometriosis. We still believe that the risk of comorbidity might be higher in women with endometriosis than that we supposed before. More research is needed to determine whether women with endometriosis are really at risk of these comorbidities

Epigenetic regulation of prostate cancer

Prostate cancer is a commonly diagnosed cancer in men and a leading cause of cancer deaths. Whilst the underlying mechanisms leading to prostate cancer are still to be determined, it is evident that both genetic and epigenetic changes contribute to the development and progression of this disease. Epigenetic changes involving DNA hypo- and hypermethylation, altered histone modifications and more recently changes in microRNA expression have been detected at a range of genes associated with prostate cancer. Furthermore, there is evidence that particular epigenetic changes are associated with different stages of the disease. Whilst early detection can lead to effective treatment, and androgen deprivation therapy has a high response rate, many tumours develop towards hormone-refractory prostate cancer, for which there is no successful treatment. Reliable markers for early detection and more effective treatment strategies are, therefore, needed. Consequently, there is a considerable interest in the potential of epigenetic changes as markers or targets for therapy in prostate cancer. Epigenetic modifiers that demethylate DNA and inhibit histone deacetylases have recently been explored to reactivate silenced gene expression in cancer. However, further understanding of the mechanisms and the effects of chromatin modulation in prostate cancer are required. In this review, we examine the current literature on epigenetic changes associated with prostate cancer and discuss the potential use of epigenetic modifiers for treatment of this disease