38 research outputs found
Contribution à l'étude de la régulation par l'hormone thyréotrope de la synthèse protéique dans la glande thyroïde
Doctorat en Sciencesinfo:eu-repo/semantics/nonPublishe
Effet des forces attractives sur la conductibilité thermique des gaz réels
Doctorat en Sciencesinfo:eu-repo/semantics/nonPublishe
Thyrotropin stimulation of a thyroid contractile protein phosphorylation
SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe
In vivo and in vitro effects of thyrotropin on ribosomal pattern of dog thyroid
The proportion of ribosomes bound to mRNA (i.e. polysomes) was expressed as the P/P+M ratio, where P and M were the polysomes and monosomes area, respectively, measured on a ribosomal density gradient centrifugation pattern. Thyrotropin both in vivo and in vitro enhanced this P/P+M ratio. The average increase of P/P+M by thyrotropin was 20 % (P 6) and L the light polysome population (14 %; P < 0.02). These effects are specific for thyrotropin, they are observed within 30 min of adding thyrotropin and they are obtained for concentrations of 1 munit/ml or higher. Cyclic AMP and dibutyryl cyclic AMP reproduced the stimulation. There is a close parallelism between these effects of thyrotropin and the activation of protein synthesis by this hormone. The rapid response to thyrotropin, as well as labeling experiments with [3H]uridine, support the hypothesis that these effects of thyrotropin bear on translation and not on transcription. It is suggested that thyrotropin rapidly activates protein synthesis in dog thyroid slices by a process mediated by cyclic AMP which bears on translation either by unmasking of heavy mRNA or by increasing the rate of initiation of protein synthesis. © 1973.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Stimulation by thyrotropin of amino acid incorporation into proteins in dog thyroid slices in vitro
SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Pattern of protein phosphorylation in rat hepatocytes stimulated by glucagon or by the Ca2+-linked glycogenolytic hormones
SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe