Cytogenetic effects of neutron therapy in patients with parotid gland tumors and relapse of breast cancer

Aim:To assess the frequency and spectrum of chromosome aberrations and micronuclei in peripheral blood lymphocytes of patients with parotid salivary gland tumors and relapse of breast cancer during the course of neutron therapy. Materials and Methods: Samples of peripheral blood were obtained from 9 patients with parotid salivary gland tumors (T3N0–3M0) and 8 patients with relapse of breast cancer before, after first fraction and at the end of neutron therapy. The treatment course specified 5.5–8.4 Gy (equivalent to 23–44 Gy of photon irradiation) with 1.3–2.2 Gy per fraction for patients with parotid salivary gland tumors and 4,8–8.0 Gy (equivalent to 30–40 Gy of photon irradiation) with 1.6 Gy per fraction for patients with relapse of breast cancer. Control group established for conventional cytogenetic analysis consisted of 15 healthy persons. Assessment of chromosome aberrations frequency was performed on routinely stained metaphase plates. Lymphocytes from the same patients were analyzed by micronucleus test in combination with fluorescent in situ hybridization (FISH) using pancentromeric DNA probe. Results: Level of chromosome aberrations and micronuclei significantly increased in lymphocytes of patients from both groups during neutron therapy (P < 0.05). This increase was mainly due to chromosome-type aberrations and centromere-negative micronuclei. The prevalent types of aberrations are in agreement with theoretical mechanisms of neutron effects on cells. Conclusion: Cytogenetic effects of fast neutron therapy in lymphocytes of patients with parotid salivary gland tumors and relapse of breast cancer were observed. A positive dynamics of radiation-induced chromosomal damages formation during the course was denoted in lymphocytes of cancer patients in both groups

Influence of plasma exposure on physical characteristics of thin films of SnO2 obtained from SnCl4 solutions with additives of NH4F and NH4OH

The electrical conductivity of tin dioxide is extremely sensitive to the state of the surface in the temperature range 300-800 K, at which oxidation-reduction reactions take place on its surface. Nanocrystalline films of tin dioxide are selectively sensitive to the presence of toxic gases, organic and certain biological molecules in the surrounding atmosphere [1]. SnO2-based films are also used as transparent conductive coatings [2]. To modify the properties of the films, alloying, heat treatment, plasma treatment is used

Analysis and optimization of photonics devices manufacturing technologies based on carbon nanotubes

The analysis and optimization of optical devices manufacturing technologies based on carbon nanotubes intended for work in the terahertz range were carried out. These processes studied in the work have practical application for the deposition of carbon nanotubes and their subsequent use as materials for prototypes of the waveguide and sensor of the terahertz range. To obtain a layer of carbon nanotubes, a chemical vapor deposition chamber was used. Various aspects of the synthesis and growth of the mechanism of CNT are considered in this article. Carbon nanotubes (CNTs) were grown on a sandwich structure based on a silicon wafer, where a layer of aluminum and copper 100 nm thick was deposited, then an iron catalyst was applied about 5 nm thick, and then copper and aluminum were deposited again, but with a thickness of 10 nm layer is also using magnetron sputtering. The growth was carried out with two variable parameters: flow rate and flow duration

Search for Heavy Neutrino in K->mu nu_h(nu_h-> nu gamma) Decay at ISTRA+ Setup

Heavy neutrino nu_h with m_h < 300MeV/c^2 can be effectively searched for in kaon decays. We put upper limits on mixing matrix element |U_mu_h}|^2 for radiatively decaying nu_h from K->mu nu_h (nu_h -> nu gamma) decay chain in the following parameter region: 30MeV/c^2 < m_h < 80MeV/c^2; 10^{-11}sec < tau_h < 10^{-9}sec. For the whole region |U_{mu h}|^2 < 5 x 10^{-5} for Majorana type of nu_h and | U_{\mu h}|^2 < 8 x 10^{-5} for the Dirac case.Comment: Published in Phys. Lett.

Актуальные вопросы экономического взаимодействия России и Белоруссии

Актуальность исследования заключается в развивающихся экономических отношениях России и Белоруссии на фоне ряда санкций, введенных США и странами Запада в 2022 году. В данной статье выявлены актуальные вопросы сотрудничества России и Белоруссии

Neutral Higgs sector of the next-to-minimal supersymmetric standard model with explicit CP violation

The neutral Higgs sector of the next-to-minimal supersymmetric standard model (NMSSM) with explicit CP violation is investigated at the 1-loop level, using the effective potential method; not only the loops involving the third generation of quarks and scalar quarks, but also the loops involving $W$ boson, charged Higgs boson, and chargino are taken into account. It is found that for some parameter values of the NMSSM the contributions from the $W$ boson, charged Higgs boson, and chargino loops may modify the masses of the neutral Higgs bosons and the mixings among them significantly, depending on the CP phase. In $e^+e^-$ collisions, the prospects for discovering neutral Higgs bosons are investigated within the context of the NMSSM with explicit CP violation when the dominant component of the lightest neutral Higgs boson is the Higgs singlet field of the NMSSM.Comment: Latex, 23 pages, 6 figure

Extraction of Kaon Formfactors from K^- -> mu^- nu_mu gamma Decay at ISTRA+ Setup

The radiative decay K->mu nu gamma has been studied at ISTRA+ setup in a new kinematical region. About 22K events of K^- -> mu^- nu_mu gamma have been observed. The sign and value of Fv-Fa have been measured for the first time. The result is Fv-Fa=0.21(4)(4).Comment: 11 pages, 21 figures, submitted to Phys. Lett.

Vacuum effects in an asymptotically uniformly accelerated frame with a constant magnetic field

In the present article we solve the Dirac-Pauli and Klein Gordon equations in an asymptotically uniformly accelerated frame when a constant magnetic field is present. We compute, via the Bogoliubov coefficients, the density of scalar and spin 1/2 particles created. We discuss the role played by the magnetic field and the thermal character of the spectrum.Comment: 17 pages. RevTe

Finite temperature behaviour of the ISS-uplifted KKLT model

We study the static phase structure of the ISS-KKLT model for moduli stabilisation and uplifting to a zero cosmological constant. Since the supersymmetry breaking sector and the moduli sector are only gravitationally coupled, we expect negligible quantum effects of the modulus upon the ISS sector, and the other way around. Under this assumption, we show that the ISS fields end up in the metastable vacua. The reason is not only that it is thermally favoured (second order phase transition) compared to the phase transition towards the supersymmetric vacua, but rather that the metastable vacua form before the supersymmetric ones. This nice feature is exclusively due to the presence of the KKLT sector. We also show that supergravity effects are negligible around the origin of the field space. Finally, we turn to the modulus sector and show that there is no destabilisation effect coming from the ISS sector.Comment: 23 pages, 3 figures, mistake corrected, one plot updated, physical conclusions unchange