Lessons Learned: Mike Leahy

Recommended Citation Sim Esmen, Yasemin (2022) Lessons Learned: Mike Leahy, Journal of Financial Crises: Vol. 4 : Iss. 4, 622-625. Available at: https://elischolar.library.yale.edu/journal-of-financial-crises/vol4/iss4/3

YPFS Lessons Learned Oral History Project: An Interview with Mike Leahy

Suggested citation form: Leahy, Mike, 2022. “Lessons Learned Interview by Yasemin Sim Esmen, October 22, 2020.†Yale Program on Financial Stability Lessons Learned Oral History Project. Transcript. https://ypfs.som.yale.edu/library/ypfs-lesson-learned-oral-history-project-interview-mike-leah

Towards a Step Change in Managing Research Data at Western Sydney University: Assessment of the Active Data Management Ecosystem

This paper describes the approach taken by Western Sydney University in the assessment of a turnkey research data management platform. Key recommendations from the Active Research Data Management Element of the Research Data Management Framework developed by the Australian Research Data Commons were implemented. WSU-derived research data are currently stored across many different silos and there is consideration of management of data through research data management plans. However, the use of metadata is not consistent and often non-existent. WSU trialled the use of the Idea package provided by Cloud Services provider Intersect, which is based on Mediaflux, for the management of research data throughout the full data lifecycle from collection to archiving. The Active Research Data Management Element provided useful insights into the assessment of Idea in the areas of data management, use of metadata, automated data workflows, research data governance and the criteria for platform selection

Metadata: A Case Study at Western Sydney University: Assessment of Metadata Schema for Active Research Data Management

Western Sydney University has engaged Cloud Services provider Intersect to provide access to Mediaflux on an Intersect research data management platform called Idea . Idea has been designed with the intention of managing research data throughout the full data lifecycle from collection to archiving. WSU-derived research data are currently stored across many different silos and there is consideration of management of data through research data management plans. However, the use of metadata is not consistent. As part of the Australian Research Data Commons (ARDC) National Data Assets Initiative, the ARDC funded a collaborative multi-university Institutional Underpinnings project to develop a national Institutional Research Data Management Framework (the Framework). Several essential Elements to the Framework were developed, one of which is the Active Research Data Management Element . The intention of this Element is to provide “institutions with guidance to ensure that research practice is efficient and impactful, and that research data is managed according to requirements such as those outlined in The Australian Code for the Responsible Conduct of Research”. Our approach at Western Sydney University in implementation of the Active Research Data Management Element of the Framework was to take the turnkey Idea platform, configure using a default metadata schema and engage with researchers in ingesting live research project datasets. This case study evaluates the metadata schema to reflect active research datasets uploaded directly from a data source to the Idea research data repository. The Idea platform provides the ability for researchers to curate, manage, protect and disseminate research data. It will also provide the capacity for handling data from research instrument platforms as increasingly, the University’s research infrastructure requires a component that automates metadata creation and storage for aspects of the research cycle

Barriers to Exercise and Nutrition for Special Olympics Athletes

Problem People with intellectual disability (ID) have higher rates of obesity. Special Olympics Vermont (SOVT) athletes compete in sports events throughout the year. Athletes may lose fitness between seasons. Their nutrition habits remain unknown. •Barriers to exercise and nutrition remain unknown. Goal We were tasked with designing a successful exercise and nutrition program for SOVT athletes.https://scholarworks.uvm.edu/comphp_gallery/1215/thumbnail.jp

Radio galaxy zoo EMU: towards a semantic radio galaxy morphology taxonomy

© 2023 The Author(s). Published by Oxford University Press on behalf of Royal Astronomical Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)We present a novel natural language processing (NLP) approach to deriving plain English descriptors for science cases otherwise restricted by obfuscating technical terminology. We address the limitations of common radio galaxy morphology classifications by applying this approach. We experimentally derive a set of semantic tags for the Radio Galaxy Zoo EMU (Evolutionary Map of the Universe) project and the wider astronomical community. We collect 8486 plain English annotations of radio galaxy morphology, from which we derive a taxonomy of tags. The tags are plain English. The result is an extensible framework, which is more flexible, more easily communicated, and more sensitive to rare feature combinations, which are indescribable using the current framework of radio astronomy classifications.Peer reviewe

Interest on excess reserves as a monetary policy instrument: the experience of foreign central banks

This paper reviews the experience of eight major foreign central banks with policy interest rates comparable to the interest rate on excess reserves paid by the Federal Reserve. We pursue two main lines of inquiry: 1) To what extent have these policy interest rates been lower bounds for short-term market rates, and 2) to what extent has tightening that included increasing these policy rates been achieved without reliance on reductions in reserves or other deposits held at the central bank? The foreign experience suggests that policy rate floors can be effective lower bounds for market rates, although incomplete access to central bank accounts and interest on them weakens this result. In addition, the foreign experience suggests that tightening by increasing the interest rate paid on central bank balances can help reduce or eliminate the need to drain balances. These results are consistent with theoretical results that show that tightening without draining is possible, irrespective of whether excess reserves are large or small.Bank reserves ; Interest rates

Human IFNAR2 deficiency : lessons for antiviral immunity

C.J.A.D. was supported by the Academy of Medical Sciences (AMS-SGCL11), the British Infection Association, and the UK NIH Research (NIHR); S.M.B.M. was supported by the Universiti Sains Malaysia Fellowship; K.R.E. and S.H. were supported by the Sir Jules Thorn Trust (12/JTA); D.F.Y., D.C.M., and R.E.R. were supported by the Wellcome Trust (101788/Z/13/Z); and A.J.S. was supported by the Medical Research Council–Arthritis Research UK Centre for Integrated Research into Musculoskeletal Ageing and NIHR Newcastle Biomedical Research Centre. J.B. receives funding from the UCLH/UCL NIHR Biomedical Research Centre. S.M. is supported by the FP7 PATHSEEK grant. J.R.B. is supported by an NIHR fellowship.Type I interferon (IFN-α/β) is a fundamental antiviral defense mechanism. Mouse models have been pivotal to understanding the role of IFN-α/β in immunity, although validation of these findings in humans has been limited. We investigated a previously healthy child with fatal encephalitis after inoculation of the live attenuated measles, mumps, and rubella (MMR) vaccine. By targeted resequencing, we identified a homozygous mutation in the high-affinity IFN-α/β receptor (IFNAR2) in the proband, as well as a newborn sibling, that rendered cells unresponsive to IFN-α/β. Reconstitution of the proband's cells with wild-type IFNAR2 restored IFN-α/β responsiveness and control of IFN-attenuated viruses. Despite the severe outcome of systemic live vaccine challenge, the proband had previously shown no evidence of heightened susceptibility to respiratory viral pathogens. The phenotype of IFNAR2 deficiency, together with similar findings in STAT2-deficient patients, supports an essential but narrow role for IFN-α/β in human antiviral immunity.PostprintPeer reviewe