3 research outputs found
A comprehensive characterization of aggravated aging-related changes in T lymphocytes and monocytes in end-stage renal disease: The iESRD study
- Author
- Bermudez S. (Selma)
- Betjes M.G.H. (Michiel)
- Chen P.-M. (Ping-Min)
- Chia J.-S. (Jean-San)
- Chiu Y.-L. (Yen-Ling)
- Chou T.-Y. (Tzu-Ying)
- Chuang Y.-F. (Yi-Fang)
- Kao K.-C. (Kung-Chi)
- Lay F.-Y. (Fang-Yun)
- Lin C.-J. (Cheng-Jui)
- Litjens N.H.R. (Nicolle)
- Pan S.-Y. (Szu-Yu)
- Peng Y.-S. (Yu-Sen)
- Shu K.-H. (Kai-Hsiang)
- Wang G. (George)
- Yang F.-J. (Feng-Jung)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of the immune system. Nevertheless, the etiology and impact of these changes in ESRD patients remain unknown. Results: Compared to healthy individuals, ESRD patients exhibit accelerated immunosenescence in both T cell and monocyte compartments, characterized by a dramatic reduction in naïve CD4+ and CD8+ T cell numbers but increase in CD8+ TEMRA cell and proinflammatory monocyte numbers. Notably, within ESRD patients, aging-related immune changes positively correlated not only with increasing age but also with longer dialysis vintage. In multivariable-adjusted logistic regression models, the combination of high terminally differentiated CD8+ T cell level and high intermediate monocyte level, as a composite predictive immunophenotype, was independently associated with prevalent coronary artery disease as well as cardiovascular disease, after adjustment for age, sex, systemic inflammation and presence of diabetes. Levels of terminally differentiated CD8+ T cells also positively correlated with the level of uremic toxin p-cresyl sulfate. Conclusions: Aging-associated adaptive and innate immune changes are aggravated in ESRD and are associated with cardiovascular diseases. For the first time, our study demonstrates the potential link between immunosenescence in ESRD and duration of exposure to the uremic milieu
Two-stage biogas production by co-digesting molasses wastewater and sewage sludge
- Author
- B Wang
- C Sundberg
- CC Wang
- CE Hernandez-Mendoza
- D Xing
- Daehyun Wee
- EF DeLong
- F Liu
- G Chinellato
- G Luo
- G Merlino
- GD Gioannis
- GL Miller
- HG Zhu
- HHP Fang
- HQ Yu
- HS Shin
- J Kang
- J Li
- JE Schmidt
- Jeonghee Yun
- JJ Lay
- JR Cole
- Jung-Yeol Lee
- JY Heo
- KW Jung
- Kyung-Suk Cho
- L Bertin
- LW Hulshoff Pol
- M Kim
- M Lee
- M Li
- MJ Park
- MS Kim
- N Ren
- P Shen
- PY Qian
- S Jaenicke
- SH Kim
- SKS Patel
- T Aragaw
- Tae Gwan Kim
- TG Kim
- V Gontcharova
- WQ Gue
- WS Lee
- X Dai
- Y Bando
- Y Ueno
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Search for neutral MSSM Higgs bosons decaying to tau pairs in pbarp collisions at sqrts=1.96 TeV
- Author
- A. Az
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- Sliwa
- Sm S. M
- Sm S. M
- Smae S. M. Ae
- Smirnov
- Smith
- Smq S. M. Q
- Snider
- Snihur
- So S. O
- So S. O
- Soderberg
- Soha
- Somalwar
- Sorin
- Sorrentino Lucia
- Sp S. P
- Sp S. P
- Sp S. P
- Sp S. P
- Sp S. P
- Spalding
- Spinella
- Sq S. Q
- Squillacioti
- Sr S. R
- Srp S. R. P
- Ss S. S
- Ssat S. S. At
- St S. T
- St S. T
- Stanitzki
- Staveris Polykalas
- Stelzer
- Stelzer Chilton
- Stentz
- Strologas
- Stuart
- Su S. U
- Su S. U
- Suh
- Sukhanov
- Sumorok
- Sun
- Suzuki
- Sw S. W
- Sw S. W
- Swbb S. W. Bb
- Sx S. X
- Sy S. Y
- Syl S. Y. L
- Tae T. Ae
- Tae T. Ae
- Taffard
- Tafirout
- Taj T. Aj
- Taj T. Aj
- Takashima
- Takeuchi
- Takikawa
- Tanaka
- Tanaka
- Taq T. Aq
- Taq T. Aq
- Tas T. As
- Tav T. Av
- Tb T. B
- Tba T. Ba
- Tbb T. Bb
- Tbd T. Bd
- Tbd T. Bd
- Tbd T. Bd
- Tbd T. Bd
- Tbf T. Bf
- Tbf T. Bf
- Tecchio
- Teng
- Terashi
- Tether
- Thom
- Thompson
- Thomson
- Tipton
- Tiwari
- Tj T. J
- Tjo T. J. O
- Tk T. K
- Tkaczyk
- Tmw T. M. W
- Toback
- Tollefson
- Tomura
- Tonelli
- Torre
- Torretta
- Tourneur
- Tp T. P
- Tp T. P
- Trischuk
- Trw T. R. W
- Tsuchiya
- Tsuno
- Tt T. T
- Turini
- Tw T. W
- Ty T. Y
- Ty T. Y
- Ty T. Y
- Tönnesmann
- Ukegawa
- Ukm U. K. M
- Unverhau
- Uozumi
- Usynin
- Uw U. W
- Uy U. Y
- Vacavant
- Vaf V. Af
- Vaiciulis
- Vak V. Ak
- Vallecorsa
- Vam V. Am
- Van V. An
- Varganov
- Vataga
- Vaw V. Aw
- Vax V. Ax
- Vbb V. Bb
- Vbb V. Bb
- Veaw V. E. Aw
- Velev
- Veramendi
- Veszpremi
- Vickey
- Vidal
- Vila
- Vilar
- Vl V. L
- Vm V. M
- Vn V. N
- Vollrath
- Volobouev
- Vp V. P
- Vq V. Q
- Wagner
- Wagner
- Wagner
- Wagner
- Wahai W. Ahai
- Wallny
- Walter
- Wan
- Wang
- Wang
- Warburton
- Ward
- Waschke
- Waters
- Watts
- Wcp W. C. P
- Weber
- Wester
- Whbh W. H. Bh
- Whitehouse
- Whiteson
- Wicklund
- Wicklund
- Williams
- Wilson
- Winer
- Wittich
- Wjo W. J. O
- Wkax W. K. Ax
- Wmad W. M. Ad
- Wolbers
- Wolfe
- Worm
- Wp W. P
- Wp W. P
- Wright
- Wtm W. T. M
- Wu
- Wy W. Y
- Wynne
- Würthwein
- Xc X. C
- Xs X. S
- Xw X. W
- Yagil
- Yamamoto
- Yamaoka
- Yamashita
- Yang
- Yang
- Yao
- Yap Y. Ap
- Yaq Y. Aq
- Yaq Y. Aq
- Yav Y. Av
- Ybd Y. Bd
- Ybd Y. Bd
- Ybf Y. Bf
- Ybh Y. Bh
- Yca Y. C. A
- Ydaaabac Y. D. Aaabac
- Yeh
- Ykm Y. K. M
- Yoh
- Yorita
- Yoshida
- Ys Y. S
- Ysax Y. S. Ax
- Yu
- Yu
- Yun
- Yy Y. Y
- Yz Y. Z
- Zanetti
- Zaw
- Zba Z. Ba
- Zetti
- Zhang
- Zhou
- Zucchelli
- Publication venue
- American Institute of Physics:2 Huntington Quadrangle, Suite 1NO1:Melville, NY 11747:(800)344-6902, (631)576-2287, EMAIL: [email protected], INTERNET: http://www.aip.org, Fax: (516)349-9704
- Publication date
- 01/01/2006
- Field of study