624 research outputs found
Graviton decay without decreasing G: a possible cause of planetary heating, expansion and evolution
A one-day symposium on new and conventional ideas in plate tectonics and Mediterranean geodynamics was held in Rome on February 19, 2003 at the headquarters of INGV. There were two main reasons for such an initiative. The first was
an invitation to Giancarlo Scalera from the «Gabriele D’Annunzio» University of Chieti to present his alternative ideas on global tectonics to final year students of the Regional Geology course. The second was a reciprocal invitation to Giusy
Lavecchia and Francesco Stoppa to explain their criticisms of the application of subduction-related models to Italian geology and to present their data on the recently discovered intra-Apennines carbonatite occurrences. It was decided to dedicate
an entire day to seminars, involving people with a more conventional approach to geodynamics, especially those involved with seismic tomography.
In the last few years, high-resolution mantle tomographic models have been widely used to unravel the geometry of subduction zones. A turning point in the field,
however, was a review paper written by Fukao et al. (Rev. Geophysics, 39, 291-323, 2001) showing that there was no clear evidence for slab subduction down to the core-mantle boundary, thus posing a major problem on the balance between the lithosphere subducted at consuming plate margins and the large amount of oceanic lithosphere accreted at diverging plate margins. This prompted the need to re-evaluate
the nature of subduction and plate margin evolution.
Accepting the theory of plate tectonics, many problems remain open, especially those regarding plate driving mechanisms and their possible link with the forces developed at the core-mantle boundary. Might these forces trigger pulsating tectonic
and magmatic activity, with mantle upwellings and large-scale emission of CO2, capable of causing dramatic changes in the composition of the atmosphere and changes at the Earth’s surface? Could these lead to major catastrophic changes in
Earth history? During the one-day symposium, a stimulating discussion took place involving different interpretations of observations, especially those relating to the geodynamics of the Mediterranean region. Although the papers in this collection do not provide unique solutions, they do, however, provide new insights into some problems and in
some cases suggest new interpretations. Many questions also arise about the relationships between the tectonics of the lithosphere and the deep mantle processes.
May the denser portions of the inner parts of the Earth transform into shallower, lighter chemical phases, with a possible increase in the Earth’s volume? May the asthenosphere
above growing plume heads be capable of dragging the overlying lithosphere? May mantle plumes be wet rather than hot? Some papers consider gravitation to be a driving mechanism for the nucleation of contractional belts and others
even doubt the compressional origin of orogens. Finally – as a link to fundamental physics – an original mechanism of energy conversion from gravitons to photons is proposed as a supply of energy for global tectonic processes.
Obviously, because of an often diverse philosophical and scientific background, it is difficult for the ideas presented in this supplement to be shared by all readers and contributors. But we hope that these ideas will help to encourage critical evaluations of some commonly accepted concepts in modern plate tectonic theory. European geoscientists have available to them an exceptional natural laboratory – the
Mediterranean and surrounding orogens – complete with all of its paradoxes and contradictions. In this natural laboratory, we hope that new evidence and new solutions to a variety of problems outside of the Mediterranean region will be found
Seismogenesis in Central Apennines, Italy: an integrated analysis of minor earthquake sequences and structural data in the Amatrice-Campotosto area
We present a seismotectonic study of the Amatrice-Campotosto area (Central Italy) based on an integrated
analysis of minor earthquake sequences, geological data and crustal rheology. The area has been affected by
three small-magnitude seismic sequences: August 1992 (M=3.9), June 1994 (M=3.7) and October 1996
(M=4.0). The hypocentral locations and fault plane solutions of the 1996 sequence are based on original data;
the seismological features of the 1992 and 1994 sequences are summarised from literature. The active WSWdipping
Mt. Gorzano normal fault is interpreted as the common seismogenic structure for the three analysed
sequences. The mean state of stress obtained by inversion of focal mechanisms (WSW-ENE-trending deviatoric
tension) is comparable to that responsible for finite Quaternary displacement, showing that the stress field
has not changed since the onset of extensional tectonics. Available morphotectonic data integrated with original
structural data show that the Mt. Gorzano Fault extends for ~28 km along strike. The along-strike displacement
profile is typical of an isolated fault, without significant internal segmentation. The strong evidence
of late Quaternary activity in the southern part of the fault (with lower displacement gradient) is explained in
this work in terms of displacement profile readjustment within a fault unable to grow further laterally. The
depth distribution of seismicity and the crustal rheology yield a thickness of ~15 km for the brittle layer. An
area of ~530 km2 is estimated for the entire Mt. Gorzano Fault surface. In historical times, the northern portion
of the fault was probably activated during the 1639 Amatrice earthquake (I = X, M~ 6.3), but this is not the
largest event we expect on the fault. We propose that a large earthquake might activate the entire 28 km long
Mt. Gorzano Fault, with an expected Mmax up to 6.7
Reaction between quinone and thiazolidine. A study on the formation mechanism of new antiproliferative quinolindiones
Reaction between quinolinquinone and thiazolidine in basic medium was investigated. 2-Arylthiazolidine-4-carboxylic acid ethyl esters undergo two different cleavages in basic medium, yielding the 1-aryl-2-azadiene and a thiolic species. In the presence of quinolinquinone, the isomeric 1-aryl-3-ethoxycarbonyl-pyridoisoquinolin-5,10-diones and 3-amino-3-ethoxycarbonyl-dihydrothienoquinolin-
4,9-diones are formed by a hetero-Diels–Alder reaction and 1,4-Michael addition reaction, respectively. A mechanism for the formation of the reaction products is presented
Draft Genome Sequences of Three Novel Staphylococcus arlettae Strains Isolated from a Disused Biological Safety Cabinet
The genome sequences of three new strains of Staphylococcus arlettae named Bari1, Bari2, and Bari3 are presented. The strains exhibited tolerance to hexavalent chromium ions. An sprC gene encoding a putative chromium transporter was present in each of the three draft genome sequences
Computer Numerical Controlled Grinding and Physical Vapor Deposition for Fused Deposition Modelled Workpieces
he use of additive manufacturing (AM) enables companies to directly produce complex end-use parts. Fused deposition modelling (FDM) is an AM technology based on an extrusion process of fabricating parts. This layer-by-layer method results in a poor surface finish, and as a result, manual finishing is often required, which consequentially reduces the definition of the geometrical features. This research proposes a novel way of achieving high surface finishing by using additive and finishing processes, followed by a physical vapor deposition (PVD) coating. Two test pieces were produced, the first one was subjected to computer numerical controlled (CNC) mechanical grinding with appropriate grades of grindstones; the second one was subjected to microsandblasting to remove excess material and the stair-stepping effect. Both test pieces were then subjected to a PVD coating process to provide a metal thin film. To benchmark the test pieces, the authors used a coordinate measure machine for dimensions and a roughness meter to verify the effectiveness of this postprocessing approach
Comparative Genomics Suggests a Taxonomic Revision of the Staphylococcus cohnii Species Complex
Staphylococcus cohnii (SC), a coagulase-negative bacterium, was first isolated in 1975 from human skin. Early phenotypic analyses led to the delineation of two subspecies (subsp.), Staphylococcus cohnii subsp. cohnii (SCC) and Staphylococcus cohnii subsp. urealyticus (SCU). SCC was considered to be specific to humans, whereas SCU apparently demonstrated a wider host range, from lower primates to humans. The type strains ATCC 29974 and ATCC 49330 have been designated for SCC and SCU, respectively. Comparative analysis of 66 complete genome sequences-including a novel SC isolate-revealed unexpected patterns within the SC complex, both in terms of genomic sequence identity and gene content, highlighting the presence of 3 phylogenetically distinct groups. Based on our observations, and on the current guidelines for taxonomic classification for bacterial species, we propose a revision of the SC species complex. We suggest that SCC and SCU should be regarded as two distinct species: SC and SU (Staphylococcus urealyticus), and that two distinct subspecies, SCC and SCB (SC subsp. barensis, represented by the novel strain isolated in Bari) should be recognized within SC. Furthermore, since large-scale comparative genomics studies recurrently suggest inconsistencies or conflicts in taxonomic assignments of bacterial species, we believe that the approach proposed here might be considered for more general application
Seismogenesis in Central Apennines, Italy: an integrated analysis of minor earthquake sequences and structural data in the Amatrice-Campotosto area
We present a seismotectonic study of the Amatrice-Campotosto area (Central Italy) based on an integrated analysis of minor earthquake sequences, geological data and crustal rheology. The area has been affected by three small-magnitude seismic sequences: August 1992 (M=3.9), June 1994 (M=3.7) and October 1996 (M=4.0). The hypocentral locations and fault plane solutions of the 1996 sequence are based on original data; the seismological features of the 1992 and 1994 sequences are summarised from literature. The active WSWdipping Mt. Gorzano normal fault is interpreted as the common seismogenic structure for the three analysed sequences. The mean state of stress obtained by inversion of focal mechanisms (WSW-ENE-trending deviatoric tension) is comparable to that responsible for finite Quaternary displacement, showing that the stress field has not changed since the onset of extensional tectonics. Available morphotectonic data integrated with original structural data show that the Mt. Gorzano Fault extends for ~28 km along strike. The along-strike displacement profile is typical of an isolated fault, without significant internal segmentation. The strong evidence of late Quaternary activity in the southern part of the fault (with lower displacement gradient) is explained in this work in terms of displacement profile readjustment within a fault unable to grow further laterally. The depth distribution of seismicity and the crustal rheology yield a thickness of ~15 km for the brittle layer. An area of ~530 km2 is estimated for the entire Mt. Gorzano Fault surface. In historical times, the northern portion of the fault was probably activated during the 1639 Amatrice earthquake (I = X, M~ 6.3), but this is not the largest event we expect on the fault. We propose that a large earthquake might activate the entire 28 km long Mt. Gorzano Fault, with an expected Mmax up to 6.7
Nanocarbon surfaces for biomedicine
The distinctive physicochemical, mechanical and electrical
properties of carbon nanostructures are currently gaining
the interest of researchers working in bioengineering and
biomedical fields. Carbon nanotubes, carbon dendrimers, graphenic
platelets and nanodiamonds are deeply studied aiming
at their application in several areas of biology and medicine.
Here we provide a summary of the carbon nanomaterials
prepared in our labs and of the fabrication techniques used to
produce several biomedical utilities, from scaffolds for tissue
growth to cargos for drug delivery and to biosensors
Depressive-like behavior is paired to monoaminergic alteration in a murine model of Alzheimer's disease
Background: Neuropsychiatric signs are critical in primary caregiving of Alzheimer patients and have not yet been fully investigated in murine models. Methods: 18-month-old 3.Tg-AD Male mice and their wild-type Male littermates (non-Tg) were used. The open field test and the elevated plus maze test were used to evaluate anxiety-like behaviors, whereas the Porsolt forced swim test, the tail suspension test, and the sucrose preference test for antidepressant/depression-coping behaviors. Neurochemical study was conducted by microdialysis in freely-moving mice, analyzing the basal and K+-stimulated monoamine output in the frontal cortex and ventral hippocampus. Moreover by immunohistochemistry, we analysed the expression of Tyrosin hydroxylase and Tryptophan hydroxylase, which play a key role in the synthesis of monoamines. Results: Aged 3.Tg-AD mice exhibited a higher duration of immobility in the forced swim and tail suspension tests (predictors of depression-like behavior) which was not attenuated by a noradrenaline reuptake inhibitor, desipramine. In the sucrose preference test, 3.Tg-AD mice showed a significantly lower sucrose preference compared to the non-Tg group, without any difference in total fluid intake. In contrast, the motor functions and anxiety-related emotional responses of 3.Tg-AD mice were normal, as detected by the open-field and elevated plus-maze tests. To strengthen these results, we then evaluated the monoaminergic neurotransmissions by in vivo microdialysis and immunohistochemistry. In particular, with the exception of the basal hippocampal dopamine levels, 3.Tg-AD mice exhibited a lower basal extracellular output of amines in the frontal cortex and ventral hippocampus and also a decreased extracellular response to K+ stimulation. Such alterations occur with obvious local amyloid-β and tau pathologies and without gross alterations in the expression of Tyrosin and Tryptophan hydroxylase. Conclusions: These results suggest that 3.Tg-AD mice exhibit changes in depression-related behavior involving aminergic neurotrasmitters and provide an animal model for investigating AD with depression
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