60 research outputs found

    In vitro cytotoxic activity of Cymbopogon citratus L. and Cymbopogon nardus L. essential oils from Togo

    Get PDF
    The leaf essential oils of Cymbopogon citratus L. and Cymbopogon nardus L. (Poaceae) from Togo were steam-distilled, analyzed for percentage composition and investigated in vitro for their potential cytotoxic activity on human epidermic cell line HaCat. The percentage composition showed that the main constituents of essential oils samples were respectively geranial (45.2%), neral (32.4%) and myrc¨ne (10.2%) for C. citratus essential oil and citronellal (35.5%), geraniol (27.9%) and citronellol (10.7%) for that of C. nardus. The in vitro cytotoxicity bioassays on human epidermic cell line HaCaT revealed that the toxicity of the essential oil from C.citratus (IC50: 150 µL.mL-1) was higher than that of the essential oil from C.nardus (IC50: 450 µL.mL-1). Pure commercial neral, geranial, and citronellal standards showed respectively the following IC50 values: 100, 250 and 300 µL.mL-1). Conversely, pure citronellol standard appeared almost non-toxic (IC50>1000 µL.mL-1), proving the major role played in synergy by neral and geranial in the overall toxicity showed by the citratus oil sample tested in this work

    Les applications cliniques, pharmacologiques et cosmétologiques des peaux reconstruites

    No full text
    BESANCON-BU Médecine pharmacie (250562102) / SudocSudocFranceF

    Impact de deux pesticides, fipronil (Régent®) et imidaclopride (Gaucho®), sur l'homme et son environnement

    No full text
    BESANCON-BU Médecine pharmacie (250562102) / SudocSudocFranceF

    L'influence du milieu environnant sur la pénétration cutanée

    No full text
    BESANCON-BU Médecine pharmacie (250562102) / SudocSudocFranceF

    Les nouveaux animaux de compagnie (NAC) (réglementation, risques et prophylaxie)

    No full text
    BESANCON-BU Médecine pharmacie (250562102) / SudocSudocFranceF

    SIDA et antioxydants (leur utilisation en tant que traitement adjuvant)

    No full text
    BESANCON-BU Médecine pharmacie (250562102) / SudocSudocFranceF

    La relation entre JunD et le stress oxydant (rôle dans le développement tumoral et implication dans la stratégie thérapeutique)

    No full text
    BESANCON-BU Médecine pharmacie (250562102) / SudocSudocFranceF

    Intérêt de la vitamine C dans l'hypertension artérielle (action antioxydante et protection du monoxyde d'azote)

    No full text
    BESANCON-BU Médecine pharmacie (250562102) / SudocSudocFranceF

    Sélénium et vieillissement (intérêts d'une supplémentation dans les maladies liées à l'âge)

    No full text
    BESANCON-BU Médecine pharmacie (250562102) / SudocSudocFranceF
    corecore