3 research outputs found
Contextualising Apartheid at the End of Empire: Repression, ‘Development’ and the Bantustans
This article examines the global dynamics of late colonialism and how these informed
South African apartheid. More specifically, it locates the programmes of mass
relocation and bantustan ‘self-government’ that characterised apartheid after 1959 in
relation to three key dimensions. Firstly, the article explores the global circulation of
idioms of ‘development’ and trusteeship in the first half of the twentieth century and its
significance in shaping segregationist policy; secondly, it situates bantustan ‘selfgovernment’
in relation to the history of decolonisation and the partitions and
federations that emerged as late colonial solutions; and, thirdly, it locates the
tightening of rural village planning in the bantustans after 1960 in relation to the
elaboration of anti-colonial liberation struggles, repressive southern African settler
politics and the Cold War. It argues that, far from developing policies that were at odds
with the global ‘wind of change’, South African apartheid during the 1960s and 1970s
reflected much that was characteristic about late colonial strategy
Standing middle cerebral artery velocity predicts cognitive function and gait speed in older adults with cognitive impairment, and is impacted by sex differences
Upright posture challenges the cerebrovascular system, leading to changes in middle cerebral artery velocity (MCAv) dynamics which are less evident at supine rest. Chronic alterations in MCAv have been linked to hypoperfusion states and the effect that this may have on cognition remains unclear. This study aimed to determine if MCAv and oscillatory metrics of MCAv (ex. pulsatility index, PI) during upright posture are i) associated with cognitive function and gait speed (GS) to a greater extent than during supine rest, and ii) are different between sexes.Beat-by-beat MCAv (transcranial Doppler ultrasound) and mean arterial pressure (MAP, plethysmography) were averaged for 30-seconds during supine-rest through a transition to standing for 53 participants (73±6yrs, 17 females). While controlling for age, multiple linear regressions predicting MoCA scores and GS from age, supine MCAv metrics, and standing MCAv metrics, were completed. Simple linear regressions predicting Montreal Cognitive Assessment (MoCA) score and GS from MCAv metrics were performed separately for females and males. Significance was set to p<0.05.Lower standing diastolic MCAv was a significant (p = 0.017) predictor of lower MoCA scores in participants with mild cognitive impairment, and this relationship only remained significant for males. Lower standing PI was associated with slower GS (p = 0.027, r=-0.306) in both sexes. Our results indicate a relationship between blunted MCAv and altered oscillatory flow profiles during standing, with lower MoCA scores and GS. These relationships were not observed in the supine position, indicating a unique relationship between standing measures of MCAv with cognitive and physical functions