DERMATITA ATOPICĂ – DISFUNCŢIA IMUNĂ ASOCIATĂ ATOPIEI

Sistemul imunitar joacă un rol complex în apărarea organismului ca răspuns la „non-self“, răspunde anormal la antigenii alergeni (hipersensibilitate şi autoimunitate) şi este caracterizat prin toleranţă imună cu lipsa de reactivitate la propriile structuri (auto). Scop. Scopul acestui studiu este de a demonstra că, în dermatita atopică, deficitul imun influenţează dezvoltarea atopiei, severitatea bolii şi dezvoltarea de comorbidităţi. Material şi metode. În urma analizei foilor de observaţie, 135 de cazuri diagnosticate cu AD au fost incluse în studiu. Analiza statistică a fost realizată cu ajutorul SPSS V20 pentru determinarea frecvenţei şi testarea ipotezelor, pentru p <0,05, prin testele T şi OneWay ANOVA. Rezultate. Din cele 135 de cazuri, 51,9% au fost copii de sex masculin şi 48,1% de copii de sex feminin, cu vârsta cuprinsă între 1 lună şi 127 luni, cu o medie de 26,21. Potrivit IgE serice totale, 64,4% dintre pacienţi au avut niveluri ridicate de IgE, 35,6% niveluri normale. În conformitate cu SCORAD, copiii au avut forma uşoară în 20,7% din cazuri, forma moderată în 70,4%, iar severă în 8,9% din cazuri. Deficitul de IgA a fost găsit în 48,1% din cazuri, iar deficitul de IgG a fost găsit în 38,5% din cazuri. Testele t de corelaţie pe eşantioane independente constată valori semnificative statistic între nivelul IgE şi deficitul de IgA, între SCORAD şi deficitul de IgG şi IgA. Marşul atopic este influenţat de valorile crescute ale IgE şi deficitul de IgA pentru un p<0,05. Concluzii. Atopia în DA poate fi influenţată de factori complecşi, atât interni, cât şi de mediu, dar acest lucru rămâne un subiect controversat. Factorii externi care acţionează pe un fundal genetic predispus la atopie poate declanşa manifestarea DA

PRINCIPLES OF FACE BURNS MANAGEMENT: PERSONAL EXPERIENCE

Aim of the study The aim of this study is to emphasize the principles of face burn management based on our personal experience correlated with published literature data. We aim to illustrate different possible approaches of treatment in order to obtain good functional and aesthetic outcomes. Material and methods The study group included 342 patients (144 females and 198 males), with ages ranging between 18 and 92 years old, hospitalized and treated in the Burn Unit from the “Sf. Spiridon” Emergency County Hospital from Iași, Romania, during december 2020 – october 2023. The inclusion criteria for the study were: patients over 18 years old, isolated burn lesions only of the face or in association with burn lesions distributed on various anatomical regions, burns of all degrees. Results The group included 144 females (42,1%) and 198 males (57,89%). The etiologies of the burns were represented by flame (123 cases) – 35,96%, scald (103 cases) – 30,11%, contact (52) – 15,20%, electrocutions (31) – 9,06% or ultraviolet exposure (33) – 9,64%. 134 patients (39,18%) had isolated lesions of the face and 208 patients (60,81%) associated other localisations as well. Out of the total number of cases, the majority (276 cases) – 69% were treated conservatory, while 31% required different forms of surgical interventions. Conclusions The management of facial burns must be multidisciplinary and early in the face of serious complications that may endanger the vital, functional and aesthetic prognosis. Periodic evaluations must be constant and involve the physical and mental status of the patient. Social, family and professional integration takes a significant place in the overall management of facial burns to limit the difficulty of reintegration of a person affected by burns

THE ADVANTAGE OF THE ALL-ON-SIX AND ALL-ON-EIGHT TECHNIQUE COMPARED TO THE ALL-ON-FOUR TECHNIQUE

Edentulism is a prevalent oral health issue that has a detrimental social and psychological impact on patients ‘quality of life. The treatment option adopted has a significant impact on the level of quality with the goal can be achieved. For edentulous patients, implant-supported fixed restorations are a well-established treatment modality. Implant dentistry philosophies and procedures have evolved and changed over the time to give esthetics and functional outcomes. Immediate loading has various advantages over traditional loading without sacrificing the quality of the output. An immediate fixed provisional promotes a high level of patient satisfaction with respect to esthetics, phonetics, mastication and psychological comfort, enabling patients to return to their normal routine and maintain quality of life within a short period of time. Without question, the optimal solution for any edentulous patient from whom it is still clinically viable to place implants is all-on-X dental implant solution. Whether All-on-four All-on-five, All-on-six or any variation of a full implant supported design, there is a best option for quality of life, long term durability, bone maintenance, health improvement and frankly happiness

OUR EXPERIENCE REGARDING PERI-IMPLANTITIS

Although dental implants are most common prosthetic treatment used to replace missing tooth, it gained considerable importance over a decade owing to the availability of advanced techniques that can help in achieving a greater success rate and much better osseointegration. The chances that the implanted tooth can be rejected due to inflammation caused by oral microflora still persist. The term peri-implantitis is used to describe a destructive inflammatory process affecting the soft and hard tissues around osseo integrated implants, leads to the formation of a peri-implant pocket and loss of supporting bone. Predisposing factors are poor plaque control, inflammation, infection, smoking, diabetes and occlusal overload. It is diagnosed on the basis of clinical and radiographic interpretation and still no definitive criteria have been proposed for the diagnosis and treatment of peri-implantitis. However treatment can be both conservative and surgical. The cumulative interceptive supportive therapy protocol serves as good guide for the treatment of the peri-implantitis. Radiological examination it is very important pre- and post-operative assessment of implant surgery. Among all radiological methods, periapical radiography (PA) and cone beam computer tomography (CBCT) are common to asses post-operative peri-implant bone defects

THE SINUS LIFT PROCEDURE APPLIED IN CASES WHERE THE THICKNESS OF THE ALVEOLAR BONE IS INSUFFICIENT USING DOUBLE PRF AS WELL AS IN THE CASE OF AN INTRASINUS MUCOCELE

Missing teeth may result in a functional and cosmetic deficit and have traditionally been replaced with dentures or bridges. Dental implants rely on the maintenance of a direct structural and functional connection between living bone and the implant surface, this is termed osseointegration. Osseointegration has undoubtedly been one of the most significant scientific breakthroughs in dentistry over the past 40 years. Insufficient bone volume is a common problem encounter in the rehabilitation of the edentulous posterior maxilla with implant-supported prostheses. The bone available for implant placement may be limited by the presence of the maxillary sinus together with loss of alveolar bone height. Bone volume may be increased by augmentation, commonly the sinus cavity is augmented with autogenous bone or biomaterials or both. Procedures are variously described in the literature as sinus lift, sinus augmentation, sinus floor elevation or augmentation of atrophic maxillary sinus. Implant placement may be combined with sinus augmentation as one-stage technique. Alternatively sinus augmentation may be carried out as some time prior to implant placement as a two-stage technique