The feasibility study for the creation of production based on technology of lost-foam casting

The problems of establishing a new foundry in Kazakhstan utilizing Lost-foam casting technology are discussed in this article. The study’s main objectives are to determine the technical and financial viability of arranging such production in the country. Calculations of the manufacturing program were carried out as part of the study, and a financial- economic model of the project was developed. The research shows that establishing such a foundry is feasible, and the project may be recommended for execution

Feasibility study of the creation of a special coke production in Kazakhstan

The article examines the issues of creating a special coke production in the country. The objectives of the study were to assess the technical and economic feasibility of organizing such production. In the course of the study, the production program, investment estimates and a model of financial and economic payback of the project were calculated. The study confirms the effectiveness of creating a special coke production in Kazakhstan, and the project itself can be recommended for implementation

Feasibility study of the creation of a special coke production in Kazakhstan

The article examines the issues of creating a special coke production in the country. The objectives of the study were to assess the technical and economic feasibility of organizing such production. In the course of the study, the production program, investment estimates and a model of financial and economic payback of the project were calculated. The study confirms the effectiveness of creating a special coke production in Kazakhstan, and the project itself can be recommended for implementation

The role of exometabolites isolated from aquatic macrophytes in the activity of oil-oxidizing microorganisms (Pseudomonas melochlora)

Oil hydrocarbons are known to be biodegradable, but the process of oil biodegradation depends on many factors. This article is intended to reveal the role exometabolites iso-lated from aquatic macrophytes in the activity of oil-oxidi-zing microorganism Pseudomonas melochlora. Amino acids, carbohydrates and organic acids influence differently the oil-oxidizing activity of P. melochlora. Addition of amino acids to growth medium resulted in increasing growth rates of bacterium and harvest. Exogenous carbohydrates also stimulated both the growth of P. melochlora and oil bio-degradation. Organic acids did not show any consistent patterns with regard to growth rate of the bacterium used, its respiration activity, and the ability to degrade the oil. © by PSP

Toxic action of petroleum and oil processing products on Daphnia magna straus

The kinetics of spontaneous transformations in crude oil (forming fractions and film, sorption, evaporation) in the aquatic medium was under laboratory studies. There have been stated the degrees of toxicity of crude oil, diesel fuel, and gasoline (petrol) to laboratory culture of D. magna. Bioassays with daphnia may be recommended to reveal the presence of petroleum and products of its processing in the water

2(5H)-Furanone Derivatives as Inhibitors of Staphylococcal Biofilms

© 2016, Springer Science+Business Media New York.The opportunistic bacteria Staphylococcus aureus and Staphylococcus epidermidis often form rigid biofilms on wounds and artificial surfaces and thereby become extremely resistant to antimicrobials. Here, we report the effect of four novel 2(5H)-furanone derivatives on the cell growth and biofilm formation by these microorganisms. Using the differential fluorescence staining of viable and dead cells, we demonstrated that furanones increase the antibacterial efficacy of chloramphenicol against both biofilm-embedded S. aureus and S. epidermidis with F35 being the most efficient compound, probably by increasing the accessibility of cells against antimicrobials. Compounds F6, F8, and F83 inhibited the biofilm formation at concentrations of 2.5–10 μg/ml, although exhibiting high cytotoxicity for human skin fibroblasts with CC50 of 0.5–1.1 μg/ml. F35 demonstrated minimal biofilm inhibition concentration of 10 μg/ml, while its cytotoxicity was ten times lower than that of the other compounds (CC50 13.1 μg/ml), suggesting its chemotype seems a promising starting point for the development of new antibiofilm agents

Amino-nitrile cleavage in the electrochemical reduction of hydeazones of aromatic aldehydes

1. Factors which determine the possibility of amino-nitrile cleavage of hydrazones on electrochemical reduction (ECR) include the basicity of the anionic product formed in the course of the ECR and the mobility of the aldehyde hydrogen which depends on the character of the electron polarization of the hydrazone fragment and the polarity of the N-N bond. 2. The primary action in amino-nitrile cleavage under conditions of ECR is the deprotonation of the azomethine fragment in the unreduced molecule by electrochemically generated strong base (anion or dianion). © 1988 Plenum Publishing Corporation

INVESTIGATION OF LIPOPHILIC COMPOUNDS OF HERBS AND ROOTS OF CICHORIUM INTYBUS L

Cichorium intybus L., a perennial herbaceous plant of Asteraceae family, is widely distributed in the flora of Russia. Aboveground and underground parts of this plant are used in scientific and traditional medicine as hypoglycemic, antioxidant, hepatoprotective remedy. In this experiment lipophilic fractions of the herb and roots of chicory by method of gas chromatography with mass spectrometry detection was investigated. 4s a result of the research in the grass we revealed the presence of 14 compounds: derivatives of higher fatty alcohols, vital, isophytol, 3,7,11,15-tetrameth- yl-l,6,10,14-hexametre-3-ol, heneicosane, polien, first identifiedD-Iimonene. In the roots of chicory ordinary identified 12 substances - derivatives oflinoleic acid, first identified a-gorunen, (1-veteranen, a-amyrin and betulin