Customized and Secure Image Steganography through Least Significant Bit Replacement

Steganography is the process of hiding a secret message within a larger one in such a way that someone can not know the presence or contents of hidden message. The purpose of Steganography is to maintain secret communication between two parties. The basic structure of Steganography is made up of three components: the “carrier”, the message, and the key. The carrier can be a painting, a digital image, an mp3 and even a TCP/IP packet among other things. It is the object that will „carry‟ hidden message. A key is used to decode/decipher/discover hidden message. This can be anything from a password, a pattern, a black-light, or even lemon juice. This system presents how Steganography is used in a modern context while a practical understanding of what Steganography is providing how to accomplish it. This paper describes the design of a data hiding structure using Steganography. In this paper, we focus on the use of Steganography within digital images using Least Significant Bit (LSB) substitution

Antimicrobials use and resistance on integrated poultry-fish farming systems in the Ayeyarwady Delta of Myanmar

Antimicrobials are used to support livestock health and productivity, but might pose a risk for the development of antimicrobial resistance; in particular, when multiple livestock species are raised together in production systems. On integrated chicken-fish farms, chickens are raised over fish ponds and poultry faeces is excreted into the ponds. We investigated antimicrobial usage and the antimicrobial susceptibility of Escherichia coli cultured from poultry faeces on 301 integrated farms in Ayeyarwady Delta of Myanmar. Antimicrobials were used by 92.4% of farmers for chickens, but they were not applied to fish. The most common antimicrobials used were Octamix (amoxicillin and colistin sulfate) on 28.4%, enrofloxacin on 21.0% and amoxicillin on 16% of farms. Overall, 83.1% (152/183) of the E. coli were resistant to at least one antimicrobial. The highest level of resistance was to amoxicillin (54.6%), tetracycline (39.9%), sulfamethoxazole/trimethoprim (35.5%) and enrofloxacin (34.4%). Multidrug resistance was identified in 42.4% of isolates. In general, we found similar levels of antimicrobial resistance in non-users of antimicrobials as in users of antimicrobials for more commonly applied antimicrobials. Overall, antimicrobial resistance was lower in chickens on these integrated farms in Myanmar, compared to poultry farms in other countries of South East and East Asia

The Contentious Politics of Anti-Muslim Scapegoating in Myanmar

Recent anti-Muslim violence in Myanmar cannot be understood primarily as a spontaneous outburst of religious feeling among the general population. Rather it was a shocking repertoire deployed by a semi-organised social movement with clear political goals, which overlapped with those of Myanmar’s military elite. In this article we trace the history of contention that saw key collective actors emerge who staged violent events and then framed them for the public. Elite competitive strategies leading to the 2015 election shaped its rhythm. A new regional player, the Rakhine Nationalities Development Party, initiated the violence. When the ruling elite failed to condemn it, a monk-led, apparently popular, chauvinistic movement expanded rapidly throughout Myanmar. Asserting the Rakhine violence as an existential threat to the Burmese nation, a moral panic effectively created a crisis where none existed. The movement then routinised itself into a de facto pro-regime, anti-National League for Democracy, theocratic political party favouring President Thein Sein’s re-election. While maintaining broad ties (but not chains of command) to military elites, it enjoyed a degree of autonomy not seen before under military rule. It ultimately failed to influence voter behaviour significantly, but the new salience of anti-Muslim chauvinism portends future conflict in the fledgling democracy

Thigh-length compression stockings and DVT after stroke

Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease

Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Background Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatory actions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19. Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospital with COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients were randomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once per day by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatment groups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment and were twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants and local study staff were not masked to the allocated treatment, but all others involved in the trial were masked to the outcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treat population. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936. Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) were eligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was 65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomly allocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall, 561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days (rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median 10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days (rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, no significant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilation or death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24). Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or other prespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restricted to patients in whom there is a clear antimicrobial indication. Funding UK Research and Innovation (Medical Research Council) and National Institute of Health Research