Utilización de pantallas multimedia en escolares de la ciudad de Corrientes

Las pantallas multimedia, desde la televisión a los nuevos medios de comunicación, son un componente importante de la vida de niños y adolescentes. El objetivo del presente estudio fue determinar las pautas de utilización de dispositivos multimedia en niños de 1º grado de dos escuelas primarias de la ciudad de Corrientes. Estudio observacional, descriptivo, transversal. La recolección de los datos se realizó a través de una encuesta a padres de los niños incluidos en el estudio que aceptaron participar voluntariamente. De las 268 encuestas analizadas el 99% de los niños utilizaban dispositivos multimedia: 71% niños televisión, 15% computadoras y tablets, 12% teléfonos celulares, 1%videojuegos y 1% no utilizaban pantallas. El 46% utilizaba pantallas entre 2 y 4 hs diarias. Durante las comidas el 53% de los menores utilizaba dispositivos multimedia mientras que el 80% los utilizaba antes de dormir. El 92% de los niños estudiados eran acompañados por adultos durante la mayor parte del tiempo de utilización de pantallas y el 68% presentaba normas para un correcto uso en el hogar. El uso de pantallas multimedia implica riesgos y beneficios de diversa índole, por lo que es fundamental el rol del médico a la hora de informar a los familiares de la necesidad de limitar el uso de pantallas y advertir sobre los riesgos de un uso excesivo

Distribution of Temperature and Strength in the Central Andean Lithosphere and Its Relationship to Seismicity and Active Deformation

We present three-dimensional (3D) models of the present-day steady-state conductive thermal field and strength distribution in the lithosphere beneath the Central Andes. Our primary objective was to investigate the influence that the structure of the Central Andean lithosphere has on its thermal and rheological state, and the relationship between the latter and the active deformation in the region. We used our previous data-driven and gravity-constrained 3D density model as starting point for the calculations. We first assigned lithology-derived thermal and rheological properties to the different divisions of the density model and defined temperature boundary conditions. We then calculated the 3D steady-state conductive thermal field and the maximum differential stresses for both brittle and ductile behaviors. We find that the thickness and composition of the crust are the main factors affecting the modeled thermal field, and consequently also the strength distribution. The orogen is characterized by a thick felsic crust with elevated temperatures and a low integrated strength, whereas the foreland and forearc are underlain by a more mafic and thinner crust with lower temperatures and a higher integrated strength. We find that most of the intraplate deformation coincides spatially with the steepest strength gradients and suggest that the high potential energy of the orogen together with the presence of rheological lateral heterogeneities produce high compressional stresses and strong strain localization along the margins of the orogen. We interpret earthquakes within the modeled ductile field to be related to the weakening effect of long-lived faults and/or the presence of seismic asperities.Fil: Ibarra, Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Geociencias Básicas, Aplicadas y Ambientales de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Geociencias Básicas, Aplicadas y Ambientales de Buenos Aires; ArgentinaFil: Prezzi, Claudia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Geociencias Básicas, Aplicadas y Ambientales de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Geociencias Básicas, Aplicadas y Ambientales de Buenos Aires; ArgentinaFil: Bott, Judith. German Research Centre for Geosciences; AlemaniaFil: Scheck Wenderoth, Magdalena. German Research Centre for Geosciences; AlemaniaFil: Strecker, Manfred. Universitat Potsdam; Alemani

Lack of robustness of textural measures obtained from 3D brain tumor MRIs impose a need for standardization

Purpose Textural measures have been widely explored as imaging biomarkers in cancer. However, their robustness under dynamic range and spatial resolution changes in brain 3D magnetic resonance images (MRI) has not been assessed. The aim of this work was to study potential variations of textural measures due to changes in MRI protocols. Materials and methods Twenty patients harboring glioblastoma with pretreatment 3D T1-weighted MRIs were included in the study. Four different spatial resolution combinations and three dynamic ranges were studied for each patient. Sixteen three-dimensional textural heterogeneity measures were computed for each patient and configuration including co-occurrence matrices (CM) features and run-length matrices (RLM) features. The coefficient of variation was used to assess the robustness of the measures in two series of experiments corresponding to (i) changing the dynamic range and (ii) changing the matrix size. Results No textural measures were robust under dynamic range changes. Entropy was the only textural feature robust under spatial resolution changes (coefficient of variation under 10% in all cases). Conclusion Textural measures of three-dimensional brain tumor images are not robust neither under dynamic range nor under matrix size changes. Standards should be harmonized to use textural features as imaging biomarkers in radiomic-based studies. The implications of this work go beyond the specific tumor type studied here and pose the need for standardization in textural feature calculation of oncological images

Synthesis of 4-Arylselanyl-1H-1,2,3-triazoles from Selenium-Containing Carbinols

In this work, we present a simple way to achieve 4-arylselanyl-1H-1,2,3-triazoles from selenium-containing carbinols in a one-pot strategy. The selenium-containing carbinols were used as starting materials to produce a range of selanyl-triazoles in moderate to good yields, including a quinoline and Zidovudine derivatives. One-pot protocols are crucial to the current concerns about waste production and solvent consumption, avoiding the isolation and purification steps of the reactive terminal selanylalkynes. We could also isolate an interesting and unprecedented by-product with one alkynylselenium moiety connected to the triazole

Encapsulation of lycopene using spray-drying and molecular inclusion processes

This study aimed to obtain encapsulated lycopene in a powder form, using either spray-drying or molecular inclusion with beta -cyclodextrin ( beta -CD) followed by freeze-drying. The encapsulation efficiency using spray-drying ranged from 94 to 96%, with an average yield of 51%, with microcapsules showing superficial indentations and lack of cracks and breakages. Lycopene- beta -CD complexes were only formed at a molar ratio of 1:4, and irregular structures of different sizes that eventually formed aggregates, similar to those of beta -CD, were observed after freeze-drying. About 50% of the initial lycopene did not form complexes with beta -CD. Lycopene purity increased from 96.4 to 98.1% after spray-drying, whereas lycopene purity decreased from 97.7 to 91.3% after complex formation and freeze-drying. Both the drying processes yielded pale-pink, dry, free-flowing powders.<br>Técnicas de encapsulamento, como "spray-drying" e formação de complexos por inclusão com ciclodextrinas, vêm sendo avaliadas para viabilizar a adição de carotenóides em sistemas hidrofílicos e aumentar a sua estabilidade durante o processamento e estocagem. Portanto, o objetivo do presente trabalho foi obter licopeno encapsulado na forma de pó, utilizando processos de "spray-drying" ou de inclusão molecular com beta -ciclodextrina (CD) seguido de liofilização. A eficiência do encapsulamento utilizando "spray-drying" variou de 94 a 96% e o rendimento médio foi de 51%, com as microcápsulas apresentando indentações superficiais, porém sem falhas ou aberturas na superfície. A formação de complexo licopeno- beta -CD ocorreu apenas quando utilizada razão molar de 1:4, e estruturas irregulares de diferentes tamanhos que eventualmente formaram agregados, similares às da beta -CD, foram observadas após liofilização. O licopeno não complexado neste processo ficou em torno de 50%. A pureza do licopeno (% área do all-trans-licopeno) aumentou de 96,4 para 98,1% após o encapsulamento, enquanto que a pureza do licopeno diminuiu de 97,7 para 91,3% após complexação e liofilização. Os dois processos de secagem resultaram em pós rosa claro, secos e com bom fluxo