Информационная система учета и анализа закупок ООО «Ярче»

Объектом исследования является документооборот производственных процессов. Целью работы – создание информационной системы учета и анализа закупок ООО "Ярче". В процессе исследования проводились: изучение структуры и документооборота ООО "Ярче", а также специфики работы отдела закупок, теоретический анализ, обзор аналогов, проектирование и разработка информационной системы, анализ проявлений вредных и опасных факторов. В результате исследования разработана информационная система, реализующая следующие функции: учет закупок, оценка надежности поставщиков, планирование закупок, анализ выполнения закупок. Реализовано 4 справочника, 4 документа с печатными формами, 8 отчетов, 1 регистр.The object of the study is the workflow of production processes. The aim of the work is to create an information system for accounting and analysis of purchases of Yarche LLC. In the course of the study, the study of the structure and workflow of Yarche LLC, as well as the specifics of the procurement department, theoretical analysis, review of analogues, design and development of an information system, analysis of the manifestations of harmful and dangerous factors, were conducted. As a result of the study, an information system has been developed that implements the functions: accounting of purchases, assessment of the reliability of suppliers, planning of purchases, analysis of the implementation of purchases. 4 reference books, 4 documents with printed forms, 8 reports, 1 register

Ethylene supports colonization of plant roots by the mutualistic fungus Piriformospora indica

The mutualistic basidiomycete Piriformospora indica colonizes roots of mono- and dicotyledonous plants, and thereby improves plant health and yield. Given the capability of P. indica to colonize a broad range of hosts, it must be anticipated that the fungus has evolved efficient strategies to overcome plant immunity and to establish a proper environment for nutrient acquisition and reproduction. Global gene expression studies in barley identified various ethylene synthesis and signaling components that were differentially regulated in P. indica-colonized roots. Based on these findings we examined the impact of ethylene in the symbiotic association. The data presented here suggest that P. indica induces ethylene synthesis in barley and Arabidopsis roots during colonization. Moreover, impaired ethylene signaling resulted in reduced root colonization, Arabidopsis mutants exhibiting constitutive ethylene signaling, -synthesis or ethylene-related defense were hyper-susceptible to P. indica. Our data suggest that ethylene signaling is required for symbiotic root colonization by P. indica

Extracorporeal life support given to a 16-year-old girl with cystic fibrosis, candida pneumonia and acute respiratory distress syndrome

History: Small bowel resection had to be performed because of an acute ileus in a 16-year old girl with mucoviscidosis. Severe respiratory insufficiency developed and she was transferred to the intensive care unit. Investigations: The clinical signs of a severe ARDS were demonstrated: Horowitz index < 200, pO(2) 57 mm Hg, FiO(2) 1,0, pCO(2) 82 mm Hg. Candida serology was positive (titer 1: 5120), and there was a leukocytosis (20000/mu l), hypalbuminemia (14 g/l) and elevation of C-reactive protein (190 mg/l). Treatment and course: Because all non invasive treatment options had failed to improve the patient's condition, an extracorporal membrane oxygenation (ECMO) device was connected. Seven days later, after the pulmonary situation had improved, the device was successfully removed; the patient was dicharged in a satisfactory condition after another month. Conclusion: ECMO is a another treatment option for serious ARDS in infection-related worsening of pulmonary cystic fibrosis

Controlled inoculation of Norway spruce (<em>Picea abies</em>) with <em>Sirococcus conigenus</em>: PCR-based quantification of the pathogen in host tissue and infection-related increase of phenolic metabolites.

Controlled inoculation of spruce seedling needle crowns and of shoots of 4-year-old spruce trees by Sirococcus conigenus led to disease symptoms (discoloration and necrosis) and to the induction of phenolic metabolites. Even upon complete infection, as proved by reisolation of the pathogen from inoculated seedlings, only 40% of the plants developed visible disease symptoms after 38 days. A Sirococcus-specific polymerase chain reaction (PCR) primer pair, SIRO1 and SIRO6, was designed based on sequences of a RAPD fragment. The primer pair permitted the detection of 1 pg fungal DNA (10-40 genomes) in 1 mg fresh weight spruce tissues (needles, bark, wood), regardless of visible disease symptoms. The amounts of the major phenolic compound of spruce needles, catechin, increased significantly in all of the five spruce provenances as a response to inoculation with Sirococcus. The second major phenolic compound, picein, increased in three of the provenances, whereas the remaining two had high concentrations to begin with and showed no reaction. Minor phenolic compounds increased in response to infection regardless of provenance. In a preliminary field study, Sirococcus infection of spruce was detectable by PCR even in the presence of massive infection by other fungi, such as Rhizospaera spp. and Lophodermium spp