Congenital paraesophageal hiatus hernia with gastric volvulus

Paraesophageal hiatus hernia is rarely seen in the neonatal period. An intrathoracic gastric volvulus complicating such a hernia is rarer. The upper gastrointestinal tract contrast study is diagnostic. Rapid diagnosis and treatment is essential. It avoids lethal complications as gastric dilatation, gangrene and perforation, which in turn may lead to cardiopulmonary arrest

Use of Sodium Chloride IP 0.65% w/v Nasal Spray for Symptom Relief in Patients after Nasal Surgery

Abstract Introduction : The use of nasal irrigation for the treatment of nose and sinus complaints has its foundations in yogic and homoeopathic traditions. There has been increasing use of saline irrigation, douches, sprays and rinsing as an adjunct to the medical management of chronic rhinosinusitis. Treatment strategies often include the use of topical saline from once to more than four times a day

CLINICAL PROFILE OF RIGHT ILIAC FOSSA LESIONS AND ITS MANAGEMENT

A hospital based prospective study was done with 50 patients to evaluate right iliac fossa lesions. Aim of the study is to study the clinical profile and various causes of right iliac fossa lesions. The most common disease in our study was appendicular mass (40%) followed by appendicular abscess (30%), iliopsoas abscess (10%), Ileocaecal tuberculosis (8%) and carcinoma cecum (6%). There was 1 case each of right undescended testis with malignant change, right ectopic kidney and Non-Hodgkin‘s lymphoma of ileum, each of these cases accounting for 2% of the total cases in our study. All patients having right iliac fossa lesions either clinically or on Ultrasonography of the abdomen. The appendicular pathology accounted for 70% of all causes of right iliac fossa mass in this study

Congenital paraesophageal hiatus hernia with gastric volvulus

Paraesophageal hiatus hernia is rarely seen in the neonatal period. An intrathoracic gastric volvulus complicating such a hernia is rarer. The upper gastrointestinal tract contrast study is diagnostic. Rapid diagnosis and treatment is essential. It avoids lethal complications as gastric dilatation, gangrene and perforation, which in turn may lead to cardiopulmonary arrest

In vitro prevention by ACE inhibitors of cataract induced by glucose

Objectives: To study, the anticataract activity of lisinopril and enalapril on cataract induced by glucose, in goat lenses. Materials and Methods: Goat lenses were incubated in artificial aqueous humor containing 55 mM glucose (cataractogenesis) with lisinopril or enalapril in different concentrations at room temperature for 72 h. Biochemical parameters studied in the lens were electrolytes (Na+, K+), Na+-K+-ATPase activity, malondialdehyde (MDA) and proteins. Results: Glucose induced opacification of goat lens began 8-10 hrs after incubation and was complete in 72-80 hrs. Cataractous lenses showed higher Na+, MDA (P< 0.001), lower Na+-K+-ATPase activity, and water-soluble protein content. Lenses treated with lisinopril or enalapril in concentrations of 1, 5, and 10 ng/ml showed higher protein (total and water soluble proteins) content and prevented formation and progress of cataract by glucose, as evidenced by biochemical parameters. Conclusion: The anticataract activity of lisinopril and enalapril may be because of the antioxidant and free radical scavenging activity, as evidenced by a decrease in MDA in treated lenses. Further in-vitro and in-vivo studies in various experimental models and long term clinical trials are required to validate the anticataract activity of ACE-inhibitors