Skin Lesion Segmentation in Dermoscopic Images with Noisy Data

We Propose a Deep Learning Approach to Segment the Skin Lesion in Dermoscopic Images. the Proposed Network Architecture Uses a Pretrained Efficient Net Model in the Encoder and Squeeze-And-Excitation Residual Structures in the Decoder. We Applied This Approach on the Publicly Available International Skin Imaging Collaboration (ISIC) 2017 Challenge Skin Lesion Segmentation Dataset. This Benchmark Dataset Has Been Widely Used in Previous Studies. We Observed Many Inaccurate or Noisy Ground Truth Labels. to Reduce Noisy Data, We Manually Sorted All Ground Truth Labels into Three Categories — Good, Mildly Noisy, and Noisy Labels. Furthermore, We Investigated the Effect of Such Noisy Labels in Training and Test Sets. Our Test Results Show that the Proposed Method Achieved Jaccard Scores of 0.807 on the Official ISIC 2017 Test Set and 0.832 on the Curated ISIC 2017 Test Set, Exhibiting Better Performance Than Previously Reported Methods. Furthermore, the Experimental Results Showed that the Noisy Labels in the Training Set Did Not Lower the Segmentation Performance. However, the Noisy Labels in the Test Set Adversely Affected the Evaluation Scores. We Recommend that the Noisy Labels Should Be Avoided in the Test Set in Future Studies for Accurate Evaluation of the Segmentation Algorithms

Improving Automatic Melanoma Diagnosis using Deep Learning-Based Segmentation of Irregular Networks

Deep Learning Has Achieved Significant Success in Malignant Melanoma Diagnosis. These Diagnostic Models Are Undergoing a Transition into Clinical Use. However, with Melanoma Diagnostic Accuracy in the Range of Ninety Percent, a Significant Minority of Melanomas Are Missed by Deep Learning. Many of the Melanomas Missed Have Irregular Pigment Networks Visible using Dermoscopy. This Research Presents an Annotated Irregular Network Database and Develops a Classification Pipeline that Fuses Deep Learning Image-Level Results with Conventional Hand-Crafted Features from Irregular Pigment Networks. We Identified and Annotated 487 Unique Dermoscopic Melanoma Lesions from Images in the ISIC 2019 Dermoscopic Dataset to Create a Ground-Truth Irregular Pigment Network Dataset. We Trained Multiple Transfer Learned Segmentation Models to Detect Irregular Networks in This Training Set. a Separate, Mutually Exclusive Subset of the International Skin Imaging Collaboration (ISIC) 2019 Dataset with 500 Melanomas and 500 Benign Lesions Was Used for Training and Testing Deep Learning Models for the Binary Classification of Melanoma Versus Benign. the Best Segmentation Model, U-Net++, Generated Irregular Network Masks on the 1000-Image Dataset. Other Classical Color, Texture, and Shape Features Were Calculated for the Irregular Network Areas. We Achieved an Increase in the Recall of Melanoma Versus Benign of 11% and in Accuracy of 2% over DL-Only Models using Conventional Classifiers in a Sequential Pipeline based on the Cascade Generalization Framework, with the Highest Increase in Recall Accompanying the Use of the Random Forest Algorithm. the Proposed Approach Facilitates Leveraging the Strengths of Both Deep Learning and Conventional Image Processing Techniques to Improve the Accuracy of Melanoma Diagnosis. Further Research Combining Deep Learning with Conventional Image Processing on Automatically Detected Dermoscopic Features is Warranted

SharpRazor: Automatic Removal Of Hair And Ruler Marks From Dermoscopy Images

Background: The removal of hair and ruler marks is critical in handcrafted image analysis of dermoscopic skin lesions. No other dermoscopic artifacts cause more problems in segmentation and structure detection. Purpose: The aim of the work is to detect both white and black hair, artifacts and finally inpaint correctly the image. Method: We introduce a new algorithm: SharpRazor, to detect hair and ruler marks and remove them from the image. Our multiple-filter approach detects hairs of varying widths within varying backgrounds, while avoiding detection of vessels and bubbles. The proposed algorithm utilizes grayscale plane modification, hair enhancement, segmentation using tri-directional gradients, and multiple filters for hair of varying widths. We develop an alternate entropy-based processing adaptive thresholding method. White or light-colored hair, and ruler marks are detected separately and added to the final hair mask. A classifier removes noise objects. Finally, a new technique of inpainting is presented, and this is utilized to remove the detected object from the lesion image. Results: The proposed algorithm is tested on two datasets, and compares with seven existing methods measuring accuracy, precision, recall, dice, and Jaccard scores. SharpRazor is shown to outperform existing methods. Conclusion: The Shaprazor techniques show the promise to reach the purpose of removing and inpaint both dark and white hair in a wide variety of lesions

Chimeranet: U-Net for Hair Detection in Dermoscopic Skin Lesion Images

Hair and ruler mark structures in dermoscopic images are an obstacle preventing accurate image segmentation and detection of critical network features. Recognition and removal of hairs from images can be challenging, especially for hairs that are thin, overlapping, faded, or of similar color as skin or overlaid on a textured lesion. This paper proposes a novel deep learning (DL) technique to detect hair and ruler marks in skin lesion images. Our proposed ChimeraNet is an encoder-decoder architecture that employs pretrained EfficientNet in the encoder and squeeze-and-excitation residual (SERes) structures in the decoder. We applied this approach at multiple image sizes and evaluated it using the publicly available HAM10000 (ISIC2018 Task 3) skin lesion dataset. Our test results show that the largest image size (448 x 448) gave the highest accuracy of 98.23 and Jaccard index of 0.65 on the HAM10000 (ISIC 2018 Task 3) skin lesion dataset, exhibiting better performance than for two well-known deep learning approaches, U-Net and ResUNet-a. We found the Dice loss function to give the best results for all measures. Further evaluated on 25 additional test images, the technique yields state-of-the-art accuracy compared to 8 previously reported classical techniques. We conclude that the proposed ChimeraNet architecture may enable improved detection of fine image structures. Further application of DL techniques to detect dermoscopy structures is warranted

Increasing Melanoma Diagnostic Confidence: Forcing the Convolutional Network to Learn from the Lesion

Deep learning implemented with convolutional network architectures can exceed specialists' diagnostic accuracy. However, whole-image deep learning trained on a given dataset may not generalize to other datasets. The problem arises because extra-lesional features - ruler marks, ink marks, and other melanoma correlates - may serve as information leaks. These extra-lesional features, discoverable by heat maps, degrade melanoma diagnostic performance and cause techniques learned on one data set to fail to generalize. We propose a novel technique to improve melanoma recognition by an EfficientNet model. The model trains the network to detect the lesion and learn features from the detected lesion. A generalizable elliptical segmentation model for lesions was developed, with an ellipse enclosing a lesion and the ellipse enclosed by an extended rectangle (bounding box). The minimal bounding box was extended by 20% to allow some background around the lesion. The publicly available International Skin Imaging Collaboration (ISIC) 2020 skin lesion image dataset was used to evaluate the effectiveness of the proposed method. Our test results show that the proposed method improved diagnostic accuracy by increasing the mean area under receiver operating characteristic curve (mean AUC) score from 0.9 to 0.922. Additionally, correctly diagnosed scores are also improved, providing better separation of scores, thereby increasing melanoma diagnostic confidence. The proposed lesion-focused convolutional technique warrants further study.Comment: 6 pages, 5 figure