Correlation between serum C-reactive protein level and endothelial function in patients with type2 diabetes mellitus

published_or_final_versio

On the mechanisms governing gas penetration into a tokamak plasma during a massive gas injection

A new 1D radial fluid code, IMAGINE, is used to simulate the penetration of gas into a tokamak plasma during a massive gas injection (MGI). The main result is that the gas is in general strongly braked as it reaches the plasma, due to mechanisms related to charge exchange and (to a smaller extent) recombination. As a result, only a fraction of the gas penetrates into the plasma. Also, a shock wave is created in the gas which propagates away from the plasma, braking and compressing the incoming gas. Simulation results are quantitatively consistent, at least in terms of orders of magnitude, with experimental data for a D 2 MGI into a JET Ohmic plasma. Simulations of MGI into the background plasma surrounding a runaway electron beam show that if the background electron density is too high, the gas may not penetrate, suggesting a possible explanation for the recent results of Reux et al in JET (2015 Nucl. Fusion 55 093013)

How does investor sentiment predict the future real estate returns of residential property in Hong Kong?

202312 bcchAccepted ManuscriptSelf-fundedPublishedGreen (AAM

Inflammation and endothelial dysfunction in patients with type 2 diabetes mellitus

Symposium on Endocrine Surger

Atorvastatin lowers C-reactive protein and improves endothelium-dependent vasodilation in type 2 diabetes mellitus

Endothelial dysfunction is frequently found in diabetic subjects. This study was performed to investigate whether atorvastatin therapy was able to reverse endothelial dysfunction in type 2 diabetes and, if so, whether the effect was due to its antiinflammatory action. Eighty patients (baseline low density lipoprotein, 4.37 ± 0.71 mmol/liter) were randomized to atorvastatin (10 mg daily for 3 months, followed by 20 mg daily for 3 months) or placebo in a double blind study. Endothelial function was assessed by high resolution vascular ultrasound, and high sensitivity C-reactive protein (CRP) was assessed by immunoturbidimetric assay. Diabetic patients had higher CRP (P < 0.01) than matched nondiabetic controls, and both endothelium-dependent and independent vasodilation were impaired (P < 0.01). Atorvastatin (10 and 20 rog) lowered plasma cholesterol by 32.9% and 38.0%, triglyceride by 15.4% and 23.1%, and low density lipoprotein by 43.4% and 50.1%, respectively. At 6 months, plasma CRP decreased in the atorvastatin group compared with baseline (P < 0.05). Endothelium-dependent vasodilation improved in the atorvastatin group compared with the placebo group (P < 0.05). The percent change in endothelium-dependent vasodilation at 6 months correlated with the percent change in CRP (r = -0.44; P < 0.05), but not with changes in plasma lipids. In conclusion, treatment with atorvastatin in type 2 diabetes led to a significant improvement in endothelium-dependent vasodilation, which might be partly related to its anti-inflammatory effect.link_to_subscribed_fulltex

Atorvastatin lowers C-reactive protein and improves endothelial dysfunction in type 2 diabetes mellitus

Symposium on Endocrine Surger

Hydrostatic reduction of childhood intussusception using ultrasound guidance: the Queen Mary Hospital technique

Que savons-nous de notre passé, de notre histoire personnelle, de nos origines ? Tout ? Rien ? Il a fallu à Philippe Grimbert 191 pages pour raconter comment il a ausculté sa généalogie, sondé les gestes de ses proches, interprété chaque mouvement afin de mettre la main sur des mystères familiaux et de livrer aux lecteurs son roman : Un secret. Auréolé du prix Goncourt des Lycéens en 2004, du Grand Prix littéraire Wizo en 2005, Un Secret est une autobiographie gonflée de solitude et de silence, où les mystères s'élucident en empruntant des sentiers qui ne sont pas nécessairement ceux de la parole