Impact of edge-removal on the centrality betweenness of the best spreaders

The control of epidemic spreading is essential to avoid potential fatal consequences and also, to lessen unforeseen socio-economic impact. The need for effective control is exemplified during the severe acute respiratory syndrome (SARS) in 2003, which has inflicted near to a thousand deaths as well as bankruptcies of airlines and related businesses. In this article, we examine the efficacy of control strategies on the propagation of infectious diseases based on removing connections within real world airline network with the associated economic and social costs taken into account through defining appropriate quantitative measures. We uncover the surprising results that removing less busy connections can be far more effective in hindering the spread of the disease than removing the more popular connections. Since disconnecting the less popular routes tend to incur less socio-economic cost, our finding suggests the possibility of trading minimal reduction in connectivity of an important hub with efficiencies in epidemic control. In particular, we demonstrate the performance of various local epidemic control strategies, and show how our approach can predict their cost effectiveness through the spreading control characteristics.Comment: 11 pages, 4 figure

Rotating Leaks in the Stadium Billiard

The open stadium billiard has a survival probability, $P(t)$, that depends on the rate of escape of particles through the leak. It is known that the decay of $P(t)$ is exponential early in time while for long times the decay follows a power law. In this work we investigate an open stadium billiard in which the leak is free to rotate around the boundary of the stadium at a constant velocity, $\omega$. It is found that $P(t)$ is very sensitive to $\omega$. For certain $\omega$ values $P(t)$ is purely exponential while for other values the power law behaviour at long times persists. We identify three ranges of $\omega$ values corresponding to three different responses of $P(t)$. It is shown that these variations in $P(t)$ are due to the interaction of the moving leak with Marginally Unstable Periodic Orbits (MUPOs)

Relationship between blood remifentanil concentration and stress hormone levels during pneumoperitoneum in patients undergoing laparoscopic cholecystectomy

The effect of remifentanil on stress response to surgery is unclear. However, there are not clinical studies investigating the relationship between blood remifentanil concentrations and stress hormones. Therefore, the aim of the present study was to assess the association between blood remifentanil concentrations measured after pneumoperitoneum and cortisol (CORT) or prolactin (PRL) ratio (intraoperative/preoperative value), in patients undergoing laparoscopic cholecystectom

Evidence for Strain-Induced Local Conductance Modulations in Single-Layer Graphene on SiO_2

Graphene has emerged as an electronic material that is promising for device applications and for studying two-dimensional electron gases with relativistic dispersion near two Dirac points. Nonetheless, deviations from Dirac-like spectroscopy have been widely reported with varying interpretations. Here we show evidence for strain-induced spatial modulations in the local conductance of single-layer graphene on SiO_2 substrates from scanning tunneling microscopic (STM) studies. We find that strained graphene exhibits parabolic, U-shaped conductance vs bias voltage spectra rather than the V-shaped spectra expected for Dirac fermions, whereas V-shaped spectra are recovered in regions of relaxed graphene. Strain maps derived from the STM studies further reveal direct correlation with the local tunneling conductance. These results are attributed to a strain-induced frequency increase in the out-of-plane phonon mode that mediates the low-energy inelastic charge tunneling into graphene

Maternal and infant infections stimulate a rapid leukocyte response in breastmilk

Breastmilk protects infants against infections; however, specific responses of breastmilk immune factors to different infections of either the mother or the infant are not well understood. Here, we examined the baseline range of breastmilk leukocytes and immunomodulatory biomolecules in healthy mother/infant dyads and how they are influenced by infections of the dyad. Consistent with a greater immunological need in the early postpartum period, colostrum contained considerable numbers of leukocytes (13–70% out of total cells) and high levels of immunoglobulins and lactoferrin. Within the first 1–2 weeks postpartum, leukocyte numbers decreased significantly to a low baseline level in mature breastmilk (0–2%) (P\u3c0.001). This baseline level was maintained throughout lactation unless the mother and/or her infant became infected, when leukocyte numbers significantly increased up to 94% leukocytes out of total cells (P\u3c0.001). Upon recovery from the infection, baseline values were restored. The strong leukocyte response to infection was accompanied by a more variable humoral immune response. Exclusive breastfeeding was associated with a greater baseline level of leukocytes in mature breastmilk. Collectively, our results suggest a strong association between the health status of the mother/infant dyad and breastmilk leukocyte levels. This could be used as a diagnostic tool for assessment of the health status of the lactating breast as well as the breastfeeding mother and infant

Probing Axions with Radiation from Magnetic Stars

Recent experiments suggest that polarized photons may couple significantly to pseudoscalar particles such as axions. We study the possible observational signatures of axion-photon coupling for radiation from magnetic stars, with particular focus on neutron stars. We present general methods for calculating the axion-photon conversion probability during propagation through a varying magnetized vacuum as well as across an inhomogeneous atmosphere. Partial axion-photon conversion may take place in the vacuum region outside the neutron star. Strong axion-photon mixing occurs due to a resonance in the atmosphere, and depending on the axion coupling strength and other parameters, significant axion-photon conversion can take place at the resonance. Such conversions may produce observable effects on the radiation spectra and polarization signals from the star. We also apply our results to axion-photon propagation in the Sun and in magnetic white dwarfs. We find that there is no appreciable conversion of solar axions to photons during the propagation.Comment: 12 pages, 11 figures. Minor changes. PRD accepte