413 research outputs found

    Emergence, Evolution and Scaling of Online Social Networks

    Get PDF
    This work was partially supported by AFOSR under Grant No. FA9550-10-1-0083, NSF under Grant No. CDI-1026710, NSF of China under Grants Nos. 61473060 and 11275003, and NBRPC under Grant No. 2010CB731403. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

    Effects of behavioral response and vaccination policy on epidemic spreading - an approach based on evolutionary-game dynamics

    Get PDF
    date of Acceptance: 23/06/2014 This work was supported by the National Natural Science Foundation of China (Grant Nos. 11331009, 11135001, 11105025). Y.-C.L. was supported by AFOSR under Grant No. FA9550-10-1-0083.Peer reviewedPublisher PD

    Connectivity of cycle matroids and bicircular matroids

    Get PDF
    A unified approach to prove former connectivity results of Tutte, Cunningham, Inukai and Weinberg, Oxley and Wagner

    1,1′-(4-Oxoheptane-1,7-di­yl)bis­(2-methyl-1H-benzimidazole) penta­hydrate

    Get PDF
    The title compound, C23H26N4O·5H2O, has noncrystallographic twofold rotation symmetry in the solid state. It crystallizes with five solvent water mol­ecules in the asymmetric unit. Four of these water mol­ecules are connected with each other via hydrogen-bonding inter­actions to form two types of centrosymmetric hexa­meric (H2O)6 rings. Via edge sharing of the hexa­mers, the water clusters thus build infinite chains that stretch parallel to the a axis. The fifth water mol­ecule provides an additional connection between the two hexa­meric (H2O)6 units via hydrogen bonds to both rings. The water mol­ecules in the channels along the a axis are also bonded via O—H⋯N hydrogen bonds to the organic units, and face-to-face π–π inter­actions [with centroid-to-centroid distances of 3.656 (1) Å and average face-to-face distances of 3.431 (5) Å] between the aromatic rings of adjacent mol­ecules complete the inter­molecular inter­actions in this structure

    Photoreceptor Cell Differentiation Requires Regulated Proteolysis of the Transcriptional Repressor Tramtrack

    Get PDF
    AbstractThe transcription repressor Tramtrack (TTK) is found in cone cells but not photoreceptor cells of the Drosophila eye. We show that down-regulation of TTK expression occurs in photoreceptor cells and is required for their fate determination. Down-regulation requires the presence of Phyllopod (PHYL), which is induced by the RAS pathway, and Seven In Absentia (SINA). Loss of either gene causes accumulation of TTK in photoreceptor cells, and TTK does not accumulate in cone cells if both PHYL and SINA are present. We report that SINA and PHYL promote ubiquitination and rapid degradation of TTK by the proteasome pathway in cell culture, and both SINA and PHYL bind to the N-terminal domain of TTK. These results argue that photoreceptor differentiation is regulated by the RAS pathway through targeted proteolysis of the TTK repressor
    corecore