41 research outputs found
Formation of virus-like particles from human cell lines exclusively expressing Influenza Neuraminidase
The minimal virus requirements for the generation of influenza virus-like particle (VLP) assembly and budding were reassessed. Using neuraminidase (NA) from the H5N1 and H1N1 subtypes, it was found that the expression of NA alone was sufficient to generate and release VLPs. Biochemical and functional characterization of the NA-containing VLPs demonstrated that they were morphologically similar to influenza virions. The NA oligomerization was comparable to that of the live virus, and the enzymic activity, whilst not required for the release of NA-VLPs, was preserved. Together, these findings indicate that NA plays a key role in virus budding and morphogenesis, and demonstrate that NA-VLPs represent a useful tool in influenza research. © 2010 SGM.link_to_OA_fulltex
Cost-effectiveness analysis of oral anti-viral drugs used for treatment of chronic hepatitis B in Turkey
Characterization of complex dielectric permittivity of concrete by gpr numerical simulation and spectral analysis
202209 bcvcAccepted ManuscriptRGCPublishe
Field validation of water-pipe leakage detection through spatial and time-lapse analysis of GPR wave velocity
202207 bcfcAccepted ManuscriptRGCPublishe
Subsurface diagnosis with time-lapse GPR slices and change detection algorithms
202101 bcrcVersion of RecordPublishe
A lab study of coupling effects of electromagnetic induction on underground utilities
202305 bckwAccepted ManuscriptOthersThe Hong Kong Polytechnic UniversityPublishe
GPR pattern recognition of shallow subsurface air voids
202207 bcfcAccepted ManuscriptRGCPublishe
Detection and imaging of city’s underground void by GPR
2017 9th International Workshop on Advanced Ground Penetrating Radar [IWAGPR], 28-30 June 2017, Edinburgh, UK.202305 bckwAccepted ManuscriptOthersHong Kong Polytechnic UniversityPublishe
Time-frequency spectral analysis of step frequency continuous wave and impulse ground penetrating radar
2016 16th International Conference on Ground Penetrating Radar (GPR), 13-16 June 2016, Hong Kong, China202305 bckwAccepted ManuscriptRGCPublishe