70 research outputs found
Toward interoperable bioscience data
© The Author(s), 2012. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Nature Genetics 44 (2012): 121-126, doi:10.1038/ng.1054.To make full use of research data, the bioscience community needs to adopt technologies and reward mechanisms that support interoperability and promote the growth of an open 'data commoning' culture. Here we describe the prerequisites for data commoning and present an established and growing ecosystem of solutions using the shared 'Investigation-Study-Assay' framework to support that vision.The authors also acknowledge
the following funding sources in particular: UK
Biotechnology and Biological Sciences Research
Council (BBSRC) BB/I000771/1 to S.-A.S. and A.T.;
UK BBSRC BB/I025840/1 to S.-A.S.; UK BBSRC
BB/I000917/1 to D.F.; EU CarcinoGENOMICS
(PL037712) to J.K.; US National Institutes of Health
(NIH) 1RC2CA148222-01 to W.H. and the HSCI;
US MIRADA LTERS DEB-0717390 and Alfred P.
Sloan Foundation (ICoMM) to L.A.-Z.; Swiss Federal
Government through the Federal Office of Education
and Science (FOES) to L.B. and I.X.; EU Innovative
Medicines Initiative (IMI) Open PHACTS 115191 to
C.T.E.; US Department of Energy (DOE) DE-AC02-
06CH11357 and Arthur P. Sloan Foundation (2011-
6-05) to J.G.; UK BBSRC SysMO-DB2 BB/I004637/1
and BBG0102181 to C.G.; UK BBSRC BB/I000933/1
to C.S. and J.L.G.; UK MRC UD99999906 to J.L.G.;
US NIH R21 MH087336 (National Institute of Mental
Health) and R00 GM079953 (National Institute of
General Medical Science) to A.L.; NIH U54 HG006097
to J.C. and C.E.S.; Australian government through
the National Collaborative Research Infrastructure
Strategy (NCRIS); BIRN U24-RR025736 and BioScholar RO1-GM083871 to G.B. and the 2009 Super
Science initiative to C.A.S
[Bronchial asthma]
Patients with asthma often suffer from multiple allergies at the same time. Additionally many patients show a specific constellation of the interaction visible in the individual history, and at the same time in the actual doctor-patient relationship as well. In this short paper we will summarize the actual knowledge about the etiology of the disease, and also delineate the possible factors involved in producing the typical asthma attack. In the second part the most important therapeutic strategies are shown, with emphasis on psychosocial elements
[Psychovegetative syndromes in clinical practice]
In this paper the author delineates the most important aspects of diagnosing and understanding various functional medical disorders. Thereby the differentiation to psychiatric morbidity should be included, and the patient should become assessed very skillfully. For these reasons, the interview, which includes biological, psychic and somatic aspects, will be able to extend understanding of such patients. Also some important therapeutic aspects are given
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