442 research outputs found
Heat flow in southernmost California and the origin of the Salton Trough
Heat flow in the Imperial Valley and adjacent crystalline rocks is very high (∼140 mW m−2). Gravity and seismic studies suggest the crust is about 23.5 km thick with the lower half composed of gabbro and the upper fourth composed of low-density sediments. Conduction through such a crust resting directly on asthenosphere would give the observed heat flow if there were no extension or sedimentation. However, both processes must have been active, as the Imperial Valley is part of the Salton Trough, a pull-apart sedimentary basin that evolved over the past 4 or 5 m.y. To investigate the interrelations of these factors, we consider a one-dimensional model of basin formation in which the lower crustal gabbro and upper crustal sediments accumulated simultaneously as the crust extended and sedimentation kept pace with isostatic subsidence. For parameters appropriate for the Salton Trough, increasing the extension rate has little effect on surface heat flow because it increases effects of heating by intrusion and cooling by sedimentation in a compensating manner; it does, however, result in progressively increasing lower crustal temperatures. Analytical results suggest that the average extensional strain rate during formation of the trough was ∼20–50%/m.y. (∼1014 s−1); slower rates are inadequate to account for the present composition of the crust, and faster rates would probably cause massive crustal melting. To achieve the differential velocities of the Pacific plate at one end of the trough and North American plate at the other with this strain rate, extension must have, on the average, been distributed (or shifted about) over a spreading region ∼150 km wide. This is about 10 times wider than the present zone of active seismicity, suggesting that the seismic pattern is ephemeral on the time scale for the trough's formation. Narrow spreading zones are typical where sustained spreading is compensated by basaltic intrusion to form the thin oceanic crust, but where such spreading occurs in thicker continental crust, broader zones of distributed extension (with smaller strain rates) may be required for heat balance. The Salton Trough model suggests that distributed extension can be associated with substantial magmatic additions to the crust; their effect on crustal buoyancy has important implications for the relation between crustal extension and subsidence
Application of Two-Part Statistics for Comparison of Sequence Variant Counts
Investigation of microbial communities, particularly human associated communities, is significantly enhanced by the vast amounts of sequence data produced by high throughput sequencing technologies. However, these data create high-dimensional complex data sets that consist of a large proportion of zeros, non-negative skewed counts, and frequently, limited number of samples. These features distinguish sequence data from other forms of high-dimensional data, and are not adequately addressed by statistical approaches in common use. Ultimately, medical studies may identify targeted interventions or treatments, but lack of analytic tools for feature selection and identification of taxa responsible for differences between groups, is hindering advancement. The objective of this paper is to examine the application of a two-part statistic to identify taxa that differ between two groups. The advantages of the two-part statistic over common statistical tests applied to sequence count datasets are discussed. Results from the t-test, the Wilcoxon test, and the two-part test are compared using sequence counts from microbial ecology studies in cystic fibrosis and from cenote samples. We show superior performance of the two-part statistic for analysis of sequence data. The improved performance in microbial ecology studies was independent of study type and sequence technology used
Development and geometry of isotropic and directional shrinkage crack patterns
We have studied shrinkage crack patterns which form when a thin layer of an
alumina/water slurry dries. Both isotropic and directional drying were studied.
The dynamics of the pattern formation process and the geometric properties of
the isotropic crack patterns are similar to what is expected from recent
models, assuming weak disorder. There is some evidence for a gradual increase
in disorder as the drying layer become thinner, but no sudden transition, in
contrast to what has been seen in previous experiments. The morphology of the
crack patterns is influenced by drying gradients and front propagation effects,
with sharp gradients having a strong orienting and ordering effect.Comment: 8 pages, 11 figures, 8 in jpg format, 3 in postscript. See also
http://mobydick.physics.utoronto.ca/mud.htm
Modeling afterslip and aftershocks following the 1992 Landers earthquake
One way to probe the rheology of the lithosphere and fault zones is to analyze the temporal evolution of deformation following a large earthquake. In such a case, the lithosphere responds to a known stress change that can be assessed from earthquake slip models constrained from seismology and geodesy. Here, we model the postseismic response of a fault zone that is assumed to obey a rate-strengthening rheology, where the frictional stress varies as aσ ln(ε), ε being the deformation rate and aσ > 0 a rheological parameter. The model is simple enough that these parameters can be estimated by inversion of postseismic geodetic data. We apply this approach to the analysis of geodetic displacements following the M_w 7.3, 1992, Landers earthquake. The model adjusts well the measured displacements and implies aσ ≈ 0.47–0.53 MPa. In addition, we show that aftershocks and afterslip follow the same temporal evolution and that the spatiotemporal distribution of aftershocks is consistent with the idea that they are driven by reloading of the seismogenic zone resulting from frictional afterslip
Order and disorder in columnar joints
Columnar joints are three-dimensional fracture networks that form in cooling basalt and several other media. The network organizes itself into ordered, mostly hexagonal columns. The same pattern can be observed on a smaller scale in desiccating starch. We show how surface boundary conditions in the desiccation of starch affect the formation of columnar joints. Under constant drying power conditions, we find a power law dependence of columnar cross-sectional area with depth, while under constant drying rate conditions this coarsening is eventually halted. Discontinuous transitions in pattern scale can be observed under constant external conditions, which may prompt a reinterpretation of similar transitions found in basalt. Starch patterns are statistically similar to those found in basalt, suggesting that mature columnar jointing patterns contain inherent residual disorder, but are statistically scale invariant
Heat flow at the spreading centers of the Guaymas Basin, Gulf of California
Fifty-four new heat flow measurements in the central troughs of the Guaymas basin support the hypothesis that they are sites of active intrusion. In the northern trough a distinct pattern of hydrothermal cooling is revealed, with venting along the western boundary fault of the trough. In the southern trough an analogous pattern is apparently superimposed upon a conductive cooling anomaly associated with a recent central intrusion. The discharge of thermal waters occurs along the boundary faults and through other faults associated with a possible horst block located in the north central floor of the southern trough. The heat flow patterns suggest that the intrusions are episodic and do not occur simultaneously along the length (15–40 km) of a spreading segment. A review of all available heat flow measurements for the Guaymas basin suggests that most of the recharge for a pervasive regional hydrothermal system is limited to the central depressions, with perhaps some contribution from pore water. The discharge of thermal waters occurs predominantly in the central depressions and possibly along the boundary transform faults and fracture zones. The regions of the basin more than a few kilometers in distance from the spreading axis, although presumably underlain by a hydrothermal system, are probably not the location of numerous vents or recharge zones
Malaria vaccine efficacy: the difficulty of detecting and diagnosing malaria
New sources of funding have revitalized efforts to control malaria. An effective vaccine would be a tremendous asset in the fight against this devastating disease and increasing financial and scientific resources are being invested to develop one. A few candidates have been tested in Phase I and II clinical trials, and several others are poised to begin trials soon. Some studies have been promising, and others disappointing. It is difficult to compare the results of these clinical trials; even independent trials of the same vaccine give highly discrepant results. One major obstacle in evaluating malaria vaccines is the difficulty of diagnosing clinical malaria. This analysis evaluates the impact of diagnostic error, particularly that introduced by microscopy, on the outcome of efficacy trials of malaria vaccines and make recommendations for improving future trials
Mineralogical characterization of protolith and fault rocks from the SAFOD Main Hole
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94865/1/grl22060.pd
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Spring temperature responses of oaks are synchronous with North Atlantic conditions during the last deglaciation
Paleoclimate proxies based on the measurement of xylem cell anatomy have rarely been developed across the temperature range of a species or applied to wood predating the most recent millennium. Here we describe wood anatomy-based proxies for spring temperatures in central North America from modern bur oaks (Quercus macrocarpa Michx.). The strong coherence of temperature signals across the species range supports the use of these proxies across thousands of years of climatic change. We also used 79 subfossil oak log cross sections from northern Missouri, ¹⁴C-dated to 9.9-13.63 ka (ka is 1000 cal yr BP), to assess the frequency of oak deposition into alluvial sediments and a subset of these oaks for a wood anatomy-based reconstruction of spring paleotemperatures. Temperatures during the Younger Dryas cold period (YD) were up to 3.5 degrees C lower than modern temperatures for that region, equivalent to or lower than those experienced at the northern edge of the modern species range. Compared to extant oaks growing at much higher [CO₂], subfossil oaks had greater vessel frequencies. Besides very low theoretical (or estimated) xylem conductivity near the beginning of the oak record near 13.6 ka, vessel frequencies greater than modern trees compensated for reduced vessel dimensions so that theoretical xylem conductivity was consistently above that of modern trees at the cold northern sites. Significant correlations were found between the frequency of ¹⁴C-dated oaks and either delta δ¹⁸O from the NGRIP (North Greenland Ice Core Project) ice core or from the Cariaco grayscale marine-sediment record from the southern Caribbean sea. Oak deposition into alluvial sediments during the YD was significantly lower than expected given the average sample depth of oaks from 9.9 to 13.6 ka. Reduced oak deposition during the YD suggests that an abrupt shift in climate reduced oak populations across the region and/or changed the rates of channel movement across drainages.Keywords: Pleistocene, Quercus macrocarpa, Holocene, Pre-Boreal, Younger Dryas, Radiocarbon, Wood anatomy, Great Plains\, USA, Phenology, Bolling-Allerod, Xylem, Bur oa
A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study
<p>Abstract</p> <p>Background</p> <p>The autism rate has recently increased to 1 in 100 children. Genetic studies demonstrate poorly understood complexity. Environmental factors apparently also play a role. Magnetic resonance imaging (MRI) studies demonstrate increased brain sizes and altered connectivity. Electroencephalogram (EEG) coherence studies confirm connectivity changes. However, genetic-, MRI- and/or EEG-based diagnostic tests are not yet available. The varied study results likely reflect methodological and population differences, small samples and, for EEG, lack of attention to group-specific artifact.</p> <p>Methods</p> <p>Of the 1,304 subjects who participated in this study, with ages ranging from 1 to 18 years old and assessed with comparable EEG studies, 463 children were diagnosed with autism spectrum disorder (ASD); 571 children were neuro-typical controls (C). After artifact management, principal components analysis (PCA) identified EEG spectral coherence factors with corresponding loading patterns. The 2- to 12-year-old subsample consisted of 430 ASD- and 554 C-group subjects (n = 984). Discriminant function analysis (DFA) determined the spectral coherence factors' discrimination success for the two groups. Loading patterns on the DFA-selected coherence factors described ASD-specific coherence differences when compared to controls.</p> <p>Results</p> <p>Total sample PCA of coherence data identified 40 factors which explained 50.8% of the total population variance. For the 2- to 12-year-olds, the 40 factors showed highly significant group differences (<it>P </it>< 0.0001). Ten randomly generated split half replications demonstrated high-average classification success (C, 88.5%; ASD, 86.0%). Still higher success was obtained in the more restricted age sub-samples using the jackknifing technique: 2- to 4-year-olds (C, 90.6%; ASD, 98.1%); 4- to 6-year-olds (C, 90.9%; ASD 99.1%); and 6- to 12-year-olds (C, 98.7%; ASD, 93.9%). Coherence loadings demonstrated reduced short-distance and reduced, as well as increased, long-distance coherences for the ASD-groups, when compared to the controls. Average spectral loading per factor was wide (10.1 Hz).</p> <p>Conclusions</p> <p>Classification success suggests a stable coherence loading pattern that differentiates ASD- from C-group subjects. This might constitute an EEG coherence-based phenotype of childhood autism. The predominantly reduced short-distance coherences may indicate poor local network function. The increased long-distance coherences may represent compensatory processes or reduced neural pruning. The wide average spectral range of factor loadings may suggest over-damped neural networks.</p
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