Le paysage dans Höhenfeuer

A regarder les films de Fredi M. Murer, on prend conscience d’une parenté entre la plupart de ses œuvres, qu’elles soient de fiction ou documentaires : les univers diégétiques sont rarement localisables avec précision. Dans Wir Bergler in den Bergen sind eigentlich nicht schuld, dass wir da sind (1974), mis à part le dialecte dans lequel ils s’expriment, aucun indice ne permet de rattacher les paysans à un canton précis. De semblable manière, la périphérie urbaine de Grauzone (1979) pourrait ..

Livres récents

Éditions, rééditions et traductions Auerbach Erich, Figura. La loi juive et la promesse chrétienne, préface et traduction de l’allemand par Diane Meur, postface de Marc de Launay, Paris, Macula, coll. « Argô ». Blumenberg Hans, Concepts en histoires, traduction de Marc de Launay, Paris, Éditions de l’Éclat, coll. « Philosophie imaginaire ». —, Théorie de l’inconceptualité, traduction de Marc de Launay, Paris, Éditions de l’Éclat, coll. « Philosophie imaginaire ». Brandes Georg, L’École romant..

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Éditions, rééditions et anthologies Cru Jean Norton, Témoins. Essai d’analyse et de critique des souvenirs de combattants édités en France de 1915 à 1928, [fac-similé de l’éd. de : Paris, Les Étincelles, 1929], Paris, Eurédit, viii-727 p. Foucault Michel, Œuvres, édition publiée sous la direction de Frédéric Gros, Paris, Gallimard, coll. « Bibliothèque de la Pléiade », 2 vol., lvii-1640 et xlii-1740 p. Klarsfeld Beate, Klarsfeld Serge, Mémoires, Paris, Fayard / Flammarion, 687 p. Lucien de Sa..

Livres récents

Éditions, rééditions et anthologies Cru Jean Norton, Témoins. Essai d’analyse et de critique des souvenirs de combattants édités en France de 1915 à 1928, [fac-similé de l’éd. de : Paris, Les Étincelles, 1929], Paris, Eurédit, viii-727 p. Foucault Michel, Œuvres, édition publiée sous la direction de Frédéric Gros, Paris, Gallimard, coll. « Bibliothèque de la Pléiade », 2 vol., lvii-1640 et xlii-1740 p. Klarsfeld Beate, Klarsfeld Serge, Mémoires, Paris, Fayard / Flammarion, 687 p. Lucien de Sa..

The Expression and Localization of N-Myc Downstream-Regulated Gene 1 in Human Trophoblasts

The protein N-Myc downstream-regulated gene 1 (NDRG1) is implicated in the regulation of cell proliferation, differentiation, and cellular stress response. NDRG1 is expressed in primary human trophoblasts, where it promotes cell viability and resistance to hypoxic injury. The mechanism of action of NDRG1 remains unknown. To gain further insight into the intracellular action of NDRG1, we analyzed the expression pattern and cellular localization of endogenous NDRG1 and transfected Myc-tagged NDRG1 in human trophoblasts exposed to diverse injuries. In standard conditions, NDRG1 was diffusely expressed in the cytoplasm at a low level. Hypoxia or the hypoxia mimetic cobalt chloride, but not serum deprivation, ultraviolet (UV) light, or ionizing radiation, induced the expression of NDRG1 in human trophoblasts and the redistribution of NDRG1 into the nucleus and cytoplasmic membranes associated with the endoplasmic reticulum (ER) and microtubules. Mutation of the phosphopantetheine attachment site (PPAS) within NDRG1 abrogated this pattern of redistribution. Our results shed new light on the impact of cell injury on NDRG1 expression patterns, and suggest that the PPAS domain plays a key role in NDRG1's subcellular distribution. © 2013 Shi et al

Arthropod communities in fungal fruitbodies are weakly structured by climate and biogeography across European beech forests

Aim The tinder fungus Fomes fomentarius is a pivotal wood decomposer in European beech Fagus sylvatica forests. The fungus, however, has regionally declined due to centuries of logging. To unravel biogeographical drivers of arthropod communities associated with this fungus, we investigated how space, climate and habitat amount structure alpha and beta diversity of arthropod communities in fruitbodies of F. fomentarius. Location Temperate zone of Europe. Taxon Arthropods. Methods We reared arthropods from fruitbodies sampled from 61 sites throughout the range of European beech and identified 13 orders taxonomically or by metabarcoding. We estimated the total number of species occurring in fruitbodies of F. fomentarius in European beech forests using the Chao2 estimator and determined the relative importance of space, climate and habitat amount by hierarchical partitioning for alpha diversity and generalized dissimilarity models for beta diversity. A subset of fungi samples was sequenced for identification of the fungus’ genetic structure. Results The total number of arthropod species occurring in fruitbodies of F. fomentarius across European beech forests was estimated to be 600. Alpha diversity increased with increasing fruitbody biomass; it decreased with increasing longitude, temperature and latitude. Beta diversity was mainly composed by turnover. Patterns of beta diversity were only weakly linked to space and the overall explanatory power was low. We could distinguish two genotypes of F. fomentarius, which showed no spatial structuring. Main conclusion Fomes fomentarius hosts a large number of arthropods in European beech forests. The low biogeographical and climatic structure of the communities suggests that fruitbodies represent a habitat that offers similar conditions across large gradients of climate and space, but are characterized by high local variability in community composition and colonized by species with high dispersal ability. For European beech forests, retention of trees with F. fomentarius and promoting its recolonization where it had declined seems a promising conservation strategy