Variação de matéria seca e de nutrientes nas folhas e nos frutos, produção de ácido ascórbico e suco, em seis cultivares de citros, durante um ciclo

De uma plantação de citros, com os cultivares T. Cravo (Citrus reticulata Blanco), L.Hamlin (Citrus sinensis (L.) Osbeck), T. Murcott (Citrus reticulata Blanco x Citrus sinensis (L.) Osbeck), L. Natal (Citrus sinensis (L.) Osbeck, L. Valencia (Citrus sinensis (L.) Osbeck) e L. Pera (Citrus sinensis (L.) Osbeck), situada na "Fazenda Sete Lagoas", no município de Mogi-Guaçu (22° 22% 46° 56'W.Gr.), em Latossolo Vermelho amarelo, fase arenosa, foram coletados frutos 30 dias após florescimento, até a idade da coleta comercial. No material coletado, foram determinadas a variação da matéria seca, a concentração dos macro e micronutrientes nas folhas adjacentes ao fruto, a extração de macro e micronutríentes pelos frutos, a produção de suco (ml) por fruto e a concentração de ácido ascórbico (mg/100 ml de suco). Concluiu-se que: 1. O aumento da matéria seca, intensifica-se a partir do segundo mês apos o florescimento; 2. Com exceção da T. Cravo, ocorre uma diminuição na produção de matéria seca no final do ciclo; 3. A concentração dos macro e micronutrientes nas folhas apresenta oscilações durante o desenvolvimento do fruto; 4. A ordem decrescente de extração de nutrientes é: K, N, Ca, Mg, P = S, Fe, B, Zn, Mn, Cu; 5. A capacidade de exportação de nutrientes pelos cultivares é, em ordem decrescente: L. Pera, L. Hamlin = T. Cravo, T. Murcott, L. Valencia, L. Natal; 6. A quantidade de suco produzido por fruto, oscila entre 43 a 95 ml; 7. A concentração de ácido ascórbico (mg/100 ml de suco), varia entre 30 a 95

Comparative constructions of similarity in Northern Samoyedic languages

The purpose of this paper is to analyze the suffixes which are used in Northern Samoyedic languages to build comparative constructions of equality. Depending on the language, the suffixes may perform three functions: word-building, form-building, and inflectional. When they mark the noun, they serve as simulative suffixes and are employed to build object comparison. In the inflectional function, these suffixes mark the verb and are a means of constructing situational comparison. In this case, they signal the formation of a special mood termed the Approximative. This paper provides a detailed description of the Approximative from paradigmatic and syntagmatic perspectives

Stromal vascular fraction cells for the treatment of critical limb ischemia: a pilot study

Abstract Background Cell-based therapy is being explored as an alternative treatment option for critical limb ischemia (CLI), a disease associated with high amputation and mortality rates and poor quality of life. However, therapeutic potential of uncultured adipose-derived stromal vascular fraction (SVF) cells has not been evaluated as a possible treatment. In this pilot study, we investigated the efficacy of multiple injections of autologous uncultured adipose-derived SVF cells to treat patients with CLI. Methods This study included 15 patients, from 35 to 77 years old, with rest pain and ulceration. SVF cells were injected once or twice in the ischemic limb along the arteries. Digital subtraction angiography was performed before and after cell therapy. The clinical follow up was carried out for the subsequent 12 months after the beginning of the treatment. Results Multiple intramuscular SVF cell injections caused no complications during the follow-up period. Clinical improvement occurred in 86.7% of patients. Two patients required major amputation, and the amputation sites healed completely. The rest of patients achieved a complete ulcer healing, pain relief, improved ankle-brachial pressure index and claudication walking distance, and had ameliorated their quality of life. Digital subtraction angiography performed before and after SVF cell therapy showed formation of numerous vascular collateral networks across affected arteries. Conclusion Results of this pilot study demonstrate that the multiple intramuscular SVF cell injections stimulate regeneration of injured tissue and are effective alternative to achieve therapeutic angiogenesis in CLI patients who are not eligible for conventional treatment. Trial registration number at ISRCTN registry, ISRCTN13001382. Retrospectively registered at 26/04/2017

Synthesis of New 1,3,4-Thiadiazole and 1,2,3,4-Oxathiadiazole Derivatives from Carbohydrate Precursors and Study of Their Effect on Tyrosinase Enzyme

5-(1,2,3,4-Tetrahydroxybutyl)-2-methylfuran-3-carbohydrazide (<strong>2</strong>) was condensed with a variety of ketones to afford carbohydrazide derivatives <strong>3</strong>–<strong>6</strong>. Acetylation of <strong>3</strong>–<strong>5</strong> afforded the acetyl derivatives <strong>7</strong>–<strong>9</strong>, while periodate oxidation of <strong>3</strong>–<strong>6</strong> afforded the formyl derivatives <strong>10</strong>–<strong>13</strong>. Acid catalyzed condensation of thiosemicarbazide or <em>o</em>-tolylthiosemicarbazide with the prepared aldehydes <strong>10</strong>–<strong>12</strong> gave thiosemicarbazone derivatives <strong>14</strong>–<strong>19</strong>. Cyclization of the latter with acetic anhydride afforded 4,5-dihydro-1,3,4-thiadiazolyl derivatives <strong>20</strong>–<strong>25</strong>. On the other hand, condensation of <em>p</em>-tosylhydrazine with the prepared aldehydes <strong>10</strong>–<strong>12</strong> afforded <em>p</em>-tosylhydrazone derivatives <strong>26</strong>–<strong>28</strong>. Cyclization of <strong>26</strong>–<strong>28</strong> with acetic anhydride afforded 1,2,3,4-oxathiadiazole derivatives <strong>29</strong>–<strong>31</strong> respectively. Moreover, the obtained results regarding to the effect of some of the prepared compounds on tyrosinase enzyme showed that the majority of these compounds having an inhibitory effect; especially compounds <strong>12</strong>, <strong>16</strong>, <strong>17</strong>, and <strong>28</strong>