7,278 research outputs found

    To what extent would the poorest consumers nutritionally and socially benefit from a global food tax and subsidy reform ? A framed field experiment based on daily food intake

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    In this paper we propose a new method in experimental economics, designed to evaluate the effectiveness of public policy incentives aimed at altering consumer behaviors. We apply this method to wide-ranging policies on food prices, which use subsidies to increase the consumption of healthy products and taxes to reduce that of unhealthy ones. Our protocol allows for observation of an individual’s daily food consumption before and after the policy. We examine two separate policies: the one subsidizes fruit and vegetables, while the other one combines taxes and subsidies. We measure their nutritional and economic impacts on the choices of low-income French consumers, compared to a reference group. Both policies have a positive effect on the nutritional quality of food choices of the two groups but initial gaps widen, especially with the subsidies. In the low-income group this can be explained by an initially unfavorable pattern and by weaker price elasticities. The redistributive effects are therefore doubly regressive. Moreover, the individual price elasticities, that the experimental approach enables us to measure, show widely diverse behaviors. They are counter-effective for close to 40% of our sample of poor women.OBESITY;PUBLIC POLICY;SOCIAL INEQUALITIES;POVERTY;INCOME REDISTRIBUTION;REGRESSIVE TAX;INDIVIDUALIZED PRICE INDEX;NUTRITIONAL TAX SYSTEM;FOOD TAX

    Quadruplexes In ‘Dicty’: Crystal Structure Of A Four-Quartet G-Quadruplex Formed By G-Rich Motif Found In The Dictyostelium Discoideum Genome

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    Guanine-rich DNA has the potential to fold into non-canonical G-quadruplex (G4) structures. Analysis of the genome of the social amoeba Dictyostelium discoideum indicates a low number of sequences with G4-forming potential (249–1055). Therefore, D. discoideum is a perfect model organism to investigate the relationship between the presence of G4s and their biological functions. As a first step in this investigation, we crystallized the dGGGGGAGGGGTACAGGGGTACAGGGG sequence from the putative promoter region of two divergent genes in D. discoideum. According to the crystal structure, this sequence folds into a four-quartet intramolecular antiparallel G4 with two lateral and one diagonal loops. The G-quadruplex core is further stabilized by a G-C Watson–Crick base pair and a A–T–A triad and displays high thermal stability (Tm \u3e 90°C at 100 mM KCl). Biophysical characterization of the native sequence and loop mutants suggests that the DNA adopts the same structure in solution and in crystalline form, and that loop interactions are important for the G4 stability but not for its folding. Four-tetrad G4 structures are sparse. Thus, our work advances understanding of the structural diversity of G-quadruplexes and yields coordinates for in silico drug screening programs and G4 predictive tools

    A large-NcN_c PNJL model with explicit ZNc_{N_c} symmetry

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    A PNJL model is built, in which the Polyakov-loop potential is explicitly ZNc_{N_c}-symmetric in order to mimic a Yang-Mills theory with gauge group SU(NcN_c). The physically expected large-NcN_c and large-TT behaviours of the thermodynamic observables computed from the Polyakov-loop potential are used to constrain its free parameters. The effective potential is eventually U(1)-symmetric when NcN_c is infinite. Light quark flavours are added by using a Nambu-Jona-Lasinio (NJL) model coupled to the Polyakov loop (the PNJL model), and the different phases of the resulting PNJL model are discussed in 't Hooft's large-NcN_c limit. Three phases are found, in agreement with previous large-NcN_c studies. When the temperature TT is larger than some deconfinement temperature TdT_d, the system is in a deconfined, chirally symmetric, phase for any quark chemical potential μ\mu. When T<TdT<T_d however, the system is in a confined phase in which chiral symmetry is either broken or not. The critical line Tχ(μ)T_\chi(\mu), signalling the restoration of chiral symmetry, has the same qualitative features than what can be obtained within a standard Nc=3N_c=3 PNJL model.Comment: To appear in Phys Rev

    Depredation of Common Eider, Somateria mollissima, Nests on a Central Beaufort Sea Barrier Island: A Case Where No One Wins

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    Along the central Beaufort Sea, Pacific Common Eiders (Somateria mollissima v-nigra) nest on unvegetated, barrier islands; often near nesting Glaucous Gulls (Larus hyperboreus). Nest-site choice likely reflects a strategy of predator avoidance: nesting on islands to avoid mammalian predators and near territorial gulls to avoid other avian predators. We observed a nesting colony of Common Eiders from first nest initiation through nesting termination on Egg Island near Prudhoe Bay, Alaska (2002 &ndash; 2003). Resident gulls depredated many eider nests, mostly during initiation. All nests failed when an Arctic Fox (Alopex lagopus) visited the island and flushed hens from their nests, exposing the eggs to depredation by the fox and gulls (resident and non-resident). Common Eiders actively defended nests from gulls, but not from foxes. Likely all three species (i.e., eiders, gulls, and foxes) ultimately achieved negligible benefit from their nest-site selection or predatory activity: (a) island nesting provided no safety from mammalian predators for eiders or gulls, (b) for Common Eiders, nesting near gulls increased egg loss, (c) for Glaucous Gulls, nesting near colonial eiders may have reduced nest success by attracting the fox, and (d) for Arctic Foxes, the depredation was of questionable value, as most eggs were cached and probably not recoverable (due to damage from fall storms). Thus, the predator-prey interactions we observed appear to be a case where little or no fitness advantage was realized by any of the species involved

    Magnetic anisotropy determination and magnetic hyperthermia properties of small Fe nanoparticles in the superparamagnetic regime

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    We report on the magnetic and hyperthermia properties of iron nanoparticles synthesized by organometallic chemistry. They are 5.5 nm in diameter and display a saturation magnetization close to the bulk one. Magnetic properties are dominated by the contribution of aggregates of nanoparticles with respect to individual isolated nanoparticles. Alternative susceptibility measurements are been performed on a low interacting system obtained after eliminating the aggregates by centrifugation. A quantitative analysis using the Gittleman s model allow a determination of the effective anisotropy Keff = 1.3 * 10^5 J.m^{-3}, more than two times the magnetocristalline value of bulk iron. Hyperthermia measurements are performed on agglomerates of nanoparticles at a magnetic field up to 66 mT and at frequencies in the range 5-300 kHz. Maximum measured SAR is 280 W/g at 300 kHz and 66 mT. Specific absorption rate (SAR) displays a square dependence with the magnetic field below 30 mT but deviates from this power law at higher value. SAR is linear with the applied frequency for mu_0H=19 mT. The deviations from the linear response theory are discussed. A refined estimation of the optimal size of iron nanoparticles for hyperthermia applications is provided using the determined effective anisotropy value

    Berry phase of magnons in textured ferromagnets

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    We study the energy spectrum of magnons in a ferromagnet with topologically nontrivial magnetization profile. In the case of inhomogeneous magnetization corresponding to a metastable state of ferromagnet, the spin-wave equation of motion acquires a gauge potential leading to a Berry phase for the magnons propagating along a closed contour. The effect of magnetic anisotropy is crucial for the Berry phase: we show that the anisotropy suppresses its magnitude, which makes the Berry phase observable in some cases, similar to the Aharonov-Bohm effect for electrons. For example, it can be observed in the interference of spin waves propagating in mesoscopic rings. We discuss the effect of domain walls on the interference in ferromagnetic rings, and propose some experiments with a certain geometry of magnetization. We also show that the nonvanishing average topological field acts on the magnons like a uniform magnetic field on electrons. It leads to the quantization of the magnon spectrum in the topological field.Comment: 8 pages, 5 figure

    Self-consistent spin-wave theory for a frustrated Heisenberg model with biquadratic exchange in the columnar phase and its application to iron pnictides

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    Recent neutron scattering studies revealed the three dimensional character of the magnetism in the iron pnictides and a strong anisotropy between the exchange perpendicular and parallel to the spin stripes. We extend studies of the J1-J2-Jc Heisenberg model with S = 1 using self-consistent spin-wave theory. A discussion of two scenarios for the instability of the columnar phase is provided. The relevance of a biquadratic exchange term between in-plane nearest neighbors is discussed. We introduce mean-field decouplings for biquadratic terms using the Dyson-Maleev and the Schwinger boson representation. Remarkably their respective mean-field theories do not lead to the same results, even at zero temperature. They are gauged in the N'eel phase in comparison to exact diagonalization and series expansion. The J1-J2-Jc model is analyzed under the influence of the biquadratic exchange Jbq and a detailed description of the staggered magnetization and of the magnetic excitations is given. The biquadratic exchange increases the renormalization of the in-plane exchange constants which enhances the anisotropy between the exchange parallel and perpendicular to the spin stripes. Applying the model to iron pnictides, it is possible to reproduce the spin-wave dispersion for CaFe2As2 in the direction perpendicular to the spin stripes and perpendicular to the planes. Discrepancies remain in the direction parallel to the spin stripes which can be resolved by passing from S = 1 to S = 2. In addition, results for the dynamical structure factor within the self-consistent spin-wave theory are provided.Comment: 18 pages, 12 figures. Updated version, several references adde

    Out of equilibrium transport through an Anderson impurity: Probing scaling laws within the equation of motion approach

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    We study non-equilibrium electron transport through a quantum impurity coupled to metallic leads using the equation of motion technique at finite temperature T. Assuming that the interactions are taking place solely in the impurity and focusing in the infinite Hubbard limit, we compute the out of equilibrium density of states and the differential conductance G_2(T,V) to test several scaling laws. We find that G_2(T,V)/G_2(T,0) is a universal function of both eV/T_K and T/T_K, being T_K the Kondo temperature. The effect of an in plane magnetic field on the splitting of the zero bias anomaly in the differential conductance is also analyzed. For a Zeeman splitting \Delta, the computed differential conductance peak splitting depends only on \Delta/T_K, and for large fields approaches the value of 2\Delta . Besides the traditional two leads setup, we also consider other configurations that mimics recent experiments, namely, an impurity embedded in a mesoscopic wire and the presence of a third weakly coupled lead. In these cases, a double peak structure of the Kondo resonance is clearly obtained in the differential conductance while the amplitude of the highest peak is shown to decrease as \ln(eV/T_K). Several features of these results are in qualitative agreement with recent experimental observations reported on quantum dots.Comment: 9 pages, 7 figure

    Description of Pairing correlation in Many-Body finite systems with density functional theory

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    Different steps leading to the new functional for pairing based on natural orbitals and occupancies proposed in ref. [D. Lacroix and G. Hupin, arXiv:1003.2860] are carefully analyzed. Properties of quasi-particle states projected onto good particle number are first reviewed. These properties are used (i) to prove the existence of such a functional (ii) to provide an explicit functional through a 1/N expansion starting from the BCS approach (iii) to give a compact form of the functional summing up all orders in the expansion. The functional is benchmarked in the case of the picked fence pairing Hamiltonian where even and odd systems, using blocking technique are studied, at various particle number and coupling strength, with uniform and random single-particle level spacing. In all cases, a very good agreement is found with a deviation inferior to 1% compared to the exact energy.Comment: 14 pages, 9 figure

    Transfemoral treatment for iliac occlusive disease with endoluminal stent-grafts

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    Objectives:Percutaneous treatment of iliac artery occlusive disease has replaced open vascular reconstruction for several indications. A balloon angioplasty with or without stent is not an option in the presence of infrainguinal extension of the disease. The authors describe a technique that allows the construction of an aorto- or iliofemoral graft through a single groin incision, using a 4 mm PTFE graft, anchoring it proximally with a Palmaz stent and dilating both to the desired diameter.Design:Retrospective non-randomised study.Materials and Methods:Nineteen procedures were performed in 16 patients mainly because of ischaemic rest pain, often with trophic skin changes or minor gangrene. Three patients had a bilateral procedure. Twelve patients had one or more associated procedures: 10 distal bypasses, one thrombectomy, one reimplantation of a distal bypass on the iliofemoral graft, one contralateral profundaplasty and two stents of the contralateral common iliac artery.Results:Two patients died, one of small bowel ischaemia and the other of a myocardial infarction. During the mean follow-up of 8.8 months, two graft thromboses occurred. In another patient bilateral stenting of a residual stenosis was necessary.Conclusions:Our experience shows that the reported technique is feasible. Whether the procedure is truly “less invasive” and the long-term results acceptable remains to be shown
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