25,275 research outputs found
Vanishing Viscosity Limits and Boundary Layers for Circularly Symmetric 2D Flows
We continue the work of Lopes Filho, Mazzucato and Nussenzveig Lopes [LMN],
on the vanishing viscosity limit of circularly symmetric viscous flow in a disk
with rotating boundary, shown there to converge to the inviscid limit in
-norm as long as the prescribed angular velocity of the
boundary has bounded total variation. Here we establish convergence in stronger
and -Sobolev spaces, allow for more singular angular velocities
, and address the issue of analyzing the behavior of the boundary
layer. This includes an analysis of concentration of vorticity in the vanishing
viscosity limit. We also consider such flows on an annulus, whose two boundary
components rotate independently.
[LMN] Lopes Filho, M. C., Mazzucato, A. L. and Nussenzveig Lopes, H. J.,
Vanishing viscosity limit for incompressible flow inside a rotating circle,
preprint 2006
The type of adjuvant in whole inactivated influenza a virus vaccines impacts vaccine-associated enhanced respiratory disease
Influenza A virus (IAV) causes a disease burden in the swine industry in the US and is a challenge to prevent due to substantial genetic and antigenic diversity of IAV that circulate in pig populations. Whole inactivated virus (WIV) vaccines formulated with oil-in-water (OW) adjuvant are commonly used in swine. However, WIV-OW are associated with vaccine-associated enhanced respiratory disease (VAERD) when the hemagglutinin and neuraminidase of the vaccine strain are mismatched with the challenge virus. Here, we assessed if different types of adjuvant in WIV vaccine formulations impacted VAERD outcome. WIV vaccines with a swine δ1-H1N2 were formulated with different commercial adjuvants: OW1, OW2, nano-emulsion squalene-based (NE) and gel polymer (GP). Pigs were vaccinated twice by the intramuscular route, 3 weeks apart, then challenged with an H1N1pdm09 three weeks post-boost and necropsied at 5 days post infection. All WIV vaccines elicited antibodies detected using the hemagglutination inhibition (HI) assay against the homologous vaccine virus, but not against the heterologous challenge virus; in contrast, all vaccinated groups had cross-reactive IgG antibody and IFN-γ responses against H1N1pdm09, with a higher magnitude observed in OW groups. Both OW groups demonstrated robust homologous HI titers and cross-reactivity against heterologous H1 viruses in the same genetic lineage. However, both OW groups had severe immunopathology consistent with VAERD after challenge when compared to NE, GP, and non-vaccinated challenge controls. None of the WIV formulations protected pigs from heterologous virus replication in the lungs or nasal cavity. Thus, although the type of adjuvant in the WIV formulation played a significant role in the magnitude of immune response to homologous and antigenically similar H1, none tested here increased the breadth of protection against the antigenically-distinct challenge virus, and some impacted immunopathology after challenge
Response.
Response:
Luís Lopes, MD, PhD
Mário Dinis-Ribeiro, MD, PhD
Carla Rolanda, MD, PhD
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doi:10.1016/j.gie.2015.01.001
Refers To:
Panagiotis Katsinelos, Georgia Lazaraki, Grigoris Chatzimavroudis, Christos Zavos, Jannis Kountouras
The endoscopic morphology of major papillae influences the selected precut technique for biliary access
Gastrointestinal Endoscopy, Volume 81, Issue 4, April 2015, Page 105
New hosts of Ralstonia solanacearum in the brazilian Amazon.
bitstream/item/102307/1/5673.pd
Chicória, hortaliça não convencional da Amazônia, nova hospedeira de Ralstonia solanacearum.
Cópia de trabalho editado em CD-ROM que contém os resumos expandidos do 42º Congresso Brasileiro de Olericultura e 11º Congresso Latino Americano de Horticultura, Uberlândia, 2002
Talinum triangulare, new host of Ralstonia solanacearum in the Brazilian Amazon.
bitstream/item/192542/1/digitalizar0155.pd
Accelerated life testing of frozen green beans (Phaseolus vulgaris, L.) quality loss kinetics: colour and starch
This study uses the information derived from a computational research for the design of accelerated life testing (ALT) to implement
experimentally the step stress methodology for the quantification of frozen green beans (Phaseolus vulgaris, L.) colour and starch degradation kinetics. Colour loss and starch degradation were successfully modelled, respectively, by a first-order reversible
and apparent first-order kinetics, under dynamic temperature fluctuations. Results show that the step stress produces models with lower regression standard errors than the conventional isothermal methodology,
increasing the accuracy of the estimated kinetic parameters. The ALT methodology, produces however, higher confidence
intervals for the estimated kinetic parameters, than the isothermal methodology (e.g. colour b-coordinate by the: (i) isothermal methodology: k₋₁₅ ºC=22.189±0.349 day⁻¹·10⁻³; and (ii) ALT methodology: k₋₁₅ ºC=22.189±0.349 day⁻¹·10⁻³). Furthermore, as expected, higher Arrhenius activation energies (Ea) were estimated by the ALT step-stress methodology, than by the isothermal methodology (e.g. Hunter total colour difference (TCDH): (i) isothermal methodology: Ea=106.272±18.67 kJmol⁻¹; and (ii) ALT methodology: Ea=140.344±18.670 kJmol⁻¹). Accelerated tests are valuable tools, that can aid the study of quality losses in frozen foods. Although ALT tests increase the complexity of data analysis, they produce satisfactory results, when applied to frozen green beans kinetics of starch and colour losses.info:eu-repo/semantics/acceptedVersio
Alcanena Industrial Waste Landfill − Description of a Portuguese Case History
Alcanena is a municipality located in the center of Portugal where about 85% of the Portuguese tanning industries are located, representing 65% of the national production. During decades the industrial waste was disposed directly in the soil and the waste waters discharged into the river without any treatment. Following the recent Portuguese environmental policy, the national authorities decided to rehabilitate this area. First, by the construction of a waste water treatment plant (WWTP) and a impermeabilized lagoon for WWTP mud deposition, then by the construction of a landfill for deposition of the tanning scraps and, finally, when the maximum capacity of the lagoon was reached by the construction of a landfill for deposition of the pre-treated WWTP muds. In this paper special importance will be given to this landfill, to the mud pre-treatment procedures and to the air and water monitoring systems
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