Search for global f-modes and p-modes in the 8B neutrino flux

The impact of global acoustic modes on the 8B neutrino flux time series is computed for the first time. It is shown that the time fluctuations of the 8B neutrino flux depend on the amplitude of acoustic eigenfunctions in the region where the 8B neutrino flux is produced: modes with low n (or order) that have eigenfunctions with a relatively large amplitude in the Sun's core, strongly affect the neutrino flux; conversely, modes with high n that have eigenfunctions with a minimal amplitude in the Sun's core have a very small impact on the neutrino flux. It was found that the global modes with a larger impact on the 8B neutrino flux have a frequency of oscillation in the interval 250 \mu Hz to 500 \mu Hz (or a period in the interval 30 minutes to 70 minutes), such as the f-modes (n=0) for the low degrees, radial modes of order n smaller or equal to 3, and the dipole mode of order n=1. Their corresponding neutrino eigenfunctions are very sensitive to the solar inner core and are unaffected by the variability of the external layers of the solar surface. If time variability of neutrinos is observed for these modes, it will lead to new ways of improving the sound speed profile inversion in the central region of the Sun.Comment: 6 pages, 3 figures, 1 tabl

Atopic Dermatitis Host and Environment Model: Revisiting Therapeutic Options

Atopic Dermatitis affects both children and adults and is a serious health concern in many countries. AD is a complex disease with host and environmental factors underlying its pathology. Its treatment is multidimensional reflecting the diverse nature of its triggers and includes emollients, topical steroids and calcineurin inhibitors among others. Immunological dysfunction can be addressed broadly with systemic immunosupressors and specifically with monoclonal antibodies. Dupilumab, which targets IL-4 and IL-13 was granted approval for treatment of moderate-to-severe AD. Biologics targeting IgE/Th2 pathways may have its role in patients with overlapping AD and asthma. Psychological distress can exacerbate symptoms and is associated with increased severity of AD. Environmental triggers, such as, allergens can be addressed in selected cases with allergic immunotherapy. In this paper, we discuss AD treatment and propose a new step-by-step approach aiming at maintaining disease control and improving quality of life.info:eu-repo/semantics/publishedVersio