39 research outputs found
The effects of Δ9-tetrahydrocannabinol on the dopamine system
Get PDFΔ(9)-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, is a pressing concern to global mental health. Patterns of use are changing drastically due to legalisation, availability of synthetic analogues (‘spice’), cannavaping and aggrandizements in the purported therapeutic effects of cannabis. Many of THC’s reinforcing effects are mediated by the dopamine system. Due to complex cannabinoid-dopamine interactions there is conflicting evidence from human and animal research fields. Acute THC causes increased dopamine release and neuron activity, whilst long-term use is associated with blunting of the dopamine system. Future research must examine the long-term and developmental dopaminergic effects of the drug
Quelle est l’association entre les caractéristiques résidentielles et du quartier et le développement de l’enfant à la maternelle?
No full textAn economic comparison of weed management systems used in small-scale organic vegetable production
No full textDevelopment of Eight-Node Curved-Side Quadrilateral Membrane Element Using Chain Direct Integration Scheme (SCDI) in Area Coordinates (MHCQ8-DI)
No full textInfluence of overnight orthokeratology lens fitting decentration on corneal topography reshaping
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Should additional domains be added to the EQ-5D health-related quality of life instrument for community-based studies? An analytical descriptive study
No full textComputation of the stress intensity factor KI for external longitudinal semi-elliptic cracks in the pipelines by FEM and XFEM methods
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