26 research outputs found
Calorie Restriction Decreases Murine and Human Pancreatic Tumor Cell Growth, Nuclear Factor-κB Activation, and Inflammation-Related Gene Expression in an Insulin-like Growth Factor-1−Dependent Manner
No full textLeucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice
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Effects of bortezomib in sensitizing human prostate cancer cell lines to NK-mediated cytotoxicity
No full textAdiposity and cancer risk: new mechanistic insights from epidemiology
Get PDFExcess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for many common adult cancers. Over the past decade, epidemiological data have shown that adiposity-cancer risk associations are specific for gender, site, geographical population, histological subtype and molecular phenotype. The biological mechanisms underpinning these associations are incompletely understood but need to take account of the specificities observed in epidemiology to better inform future prevention strategies
Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state
No full textBortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism
No full textWeight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance
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