18 research outputs found
Solid-state NMR chemical shift assignments for AL-09 VL immunoglobulin light chain fibrils
No full textDifferential recruitment efficacy of patient-derived amyloidogenic and myeloma light chain proteins by synthetic fibrilsâA metric for predicting amyloid propensity
No full textConcurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity
No full textEffect of amino acid mutations on the conformational dynamics of amyloidogenic immunoglobulin light-chains: A combined NMR and in silico study
No full textCryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis
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Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
No full textDrug Development in Conformational Diseases: A Novel Family of Chemical Chaperones that Bind and Stabilise Several Polymorphic Amyloid Structures
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