53 research outputs found
Developmental malformation of the corpus callosum: a review of typical callosal development and examples of developmental disorders with callosal involvement
This review provides an overview of the involvement of the corpus callosum (CC) in a variety of developmental disorders that are currently defined exclusively by genetics, developmental insult, and/or behavior. I begin with a general review of CC development, connectivity, and function, followed by discussion of the research methods typically utilized to study the callosum. The bulk of the review concentrates on specific developmental disorders, beginning with agenesis of the corpus callosum (AgCC)—the only condition diagnosed exclusively by callosal anatomy. This is followed by a review of several genetic disorders that commonly result in social impairments and/or psychopathology similar to AgCC (neurofibromatosis-1, Turner syndrome, 22q11.2 deletion syndrome, Williams yndrome, and fragile X) and two forms of prenatal injury (premature birth, fetal alcohol syndrome) known to impact callosal development. Finally, I examine callosal involvement in several common developmental disorders defined exclusively by behavioral patterns (developmental language delay, dyslexia, attention-deficit hyperactive disorder, autism spectrum disorders, and Tourette syndrome)
Reproductive health indicators of fishes from Pennsylvania watersheds: association with chemicals of emerging concern
Changes in the Amplitude of Endocardial Electrograms Following Defibrillator Discharge: Comparison of Two Lead Systems
Language as a Predictor of Motor Recovery: The Case for a More Global Approach to Stroke Rehabilitation
X-ray microtomography and linear discriminant analysis enable detection of embolism-related acoustic emissions
Formation of target-specific neuronal projections in organotypic slice cultures from rat visual cortex
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