12 research outputs found

    The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology.

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    Mitochondrial Ca(2+) uptake is crucial for an array of cellular functions while an imbalance can elicit cell death. In this chapter, we briefly reviewed the various modes of mitochondrial Ca(2+) uptake and our current understanding of mitochondrial Ca(2+) homeostasis in regards to cell physiology and pathophysiology. Further, this chapter focuses on the molecular identities, intracellular regulators as well as the pharmacology of mitochondrial Ca(2+) uniporter complex

    Sociopolitical Discontinuity in the Near East C. 2200 B.C.E.: Scenarios from Palestine and Egypt

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    The role of mitochondria in metabolic disease: a special emphasis on heart dysfunction

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