9 research outputs found

    Introduction: Biopharmaceutics and pharmacokinetics

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    Biopharmaceutics and pharmacokinetics are pharmaceutical disciplines useful to improve the outcome of drug therapies, assist drug product development, and establish pharmacokinetics-pharmacodynamics models and in vitro-in vivo correlations. Here, we introduce some essential lexicon that will be used throughout this volume and discuss the relationship between drug exposure and pharmacological response, in the framework of the free drug theory/hypothesis.Fil: Talevi, Alan. Universidad Nacional de La Plata. Facultad de Ciencas Exactas. Laboratorio de Investigación y Desarrollo de Bioactivos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Quiroga, Pablo A. M.. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biológicas. Cátedra de Control de Calidad de Medicamentos; Argentin

    Antiparkinsonian dopamine agonists: a review of the pharmacokinetics and neuropharmacology in animals and humans

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