28 research outputs found
Vegetative development and content of calcium, potassium, and sodium in watermelon under salinity stress on organic substrates
Oviposition preference of the neotropical brown stink bug Euschistus heros on artificial substrates of different colors
Avaliação do efeito do bagaço de cana-de-açĂșcar in natura obtido por dois mĂ©todos sobre o desempenho e o comportamento ingestivo de bovinos de corte
Implementação do Banco de Dados DEDALUS, do Sistema Integrado de Bibliotecas da Universidade de São Paulo
CaracterĂsticas da Carcaça e Qualidade da Carne de Tourinhos Alimentados com Dietas de Alta Energia
Trophic ecology of Hemigrammus marginatus Ellis, 1911 (Characiformes, Characidae) in a conserved tropical stream
Coeficiente de digestibilidade e caracterĂsticas ruminais de bovinos alimentados com raçÔes contendo resĂduo de cervejaria fermentado
Maternal protein restriction affects gene expression and enzyme activity of intestinal disaccharidases in adult rat offspring
This study investigated the consequences of intrauterine protein restriction on the gastrointestinal tract and particularly on the gene expression and activity of intestinal disaccharidases in the adult offspring. Wistar rat dams were fed isocaloric diets containing 6% protein (restricted, n = 8) or 17% protein (control, n = 8) throughout gestation. Male offspring (n = 5-8 in each group) were evaluated at 3 or 16 weeks of age. Maternal protein restriction during pregnancy produced offspring with growth restriction from birth (5.7 ± 0.1 vs 6.3 ± 0.1â
g; mean ± SE) to weaning (42.4 ± 1.3 vs 49.1 ± 1.6â
g), although at 16 weeks of age their body weight was similar to control (421.7 ± 8.9 and 428.5 ± 8.5â
g). Maternal protein restriction also increased lactase activity in the proximal (0.23 ± 0.02 vs 0.15 ± 0.02), medial (0.30 ± 0.06 vs 0.14 ± 0.01) and distal (0.43 ± 0.07 vs 0.07 ± 0.02 U·g-1·min-1) small intestine, and mRNA lactase abundance in the proximal intestine (7.96 ± 1.11 vs 2.38 ± 0.47 relative units) of 3-week-old offspring rats. In addition, maternal protein restriction increased sucrase activity (1.20 ± 0.02 vs 0.91 ± 0.02 U·g-1·min-1) and sucrase mRNA abundance (4.48 ± 0.51 vs 1.95 ± 0.17 relative units) in the duodenum of 16-week-old rats. In conclusion, the present study shows for the first time that intrauterine protein restriction affects gene expression of intestinal enzymes in offspring