Comunidades E Ocorrência De Répteis Squamata Em Diferentes Tipos De Vegetação Da Serra De São José, Minas Gerais, Brasil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)The objective of the present study was to learn which species of Squamata reptiles occur in Protected Area São José, in Tiradentes, Minas Gerais, Brazil. Between November 2009 and December 2010 reptiles were captured. In total 157 specimens were recorded of 29 species, 16 snakes, 12 lizards and one amphisbaena. Among the snakes, Dipsadidae showed the greatest richness, with a total of nine species. The group of snakes had the highest number of species present in the community, but 79% of sampled specimens were lizards, Enyalius bilineatus being the most abundant species, with 21% of occurrence. The area with the highest richness was the Cerradão. The lower abundance was found in the Gallery Forest area (n=14), but it was the vegetation type with the highest equitability. Areas of Cerradão and Cerrado sensu strictu showed the most similarity. In these areas five species were recorded in common, Bothrops neuwiedi (n=3) being the only species of snake, and the two species of lizards most abundant in both environments were Enyalius bilineatus (n=32) and Ameivula ocellifera (n=19). Ophiodes striatus and Xenodon merremii were common to Cerradão and Dirty Field areas. There was no species recorded that were common to the environments of Cerrado and Dirty Field but two species not sympatric were found of the same genus, Tropidurus torquatus, which was found only in the Cerrado sensu strictu and Tropidurus itambere exclusively in Dirty Field. Since none of the rarefaction curves reached full asymptote, this highlights the need for further study due to the high probability of new species being recorded for the studied area. © 2017, Universidade Estadual de Campinas UNICAMP. All rights reserved.171CAPES, Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorCNPq, Conselho Nacional de Desenvolvimento Científico e TecnológicoAPQ-01992-09, FAPEMIG, Fundação de Amparo á Pesquisa do Estado de Minas GeraisIBAMA, Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais RenováveisCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Anadenanthera colubrina vell brenan : anti-candida and antibiofilm activities, toxicity and therapeutical action

We evaluated the antifungal and antibiofilm potential of the hydroalcoholic extract of bark from Anadenanthera colubrina (vell.) Brenan, known as Angico, against Candida spp. Antifungal activity was evaluated using the microdilution technique through the Minimum Inhibitory and Fungicide Concentrations (MIC and MFC). The antibiofilm potential was tested in mature biofilms formed by Candida species and analyzed through the counting of CFU/mL and scanning electron micrograph (SEM). In vivo toxicity and therapeutic action was evaluated in the Galleria mellonella model. The treatment with the extract, in low doses, was able to reduce the growth of planktonic cells of Candida species. MIC values range between 19.5 and 39 µg/mL and MFC values range between 79 and 625 µg/mL. In addition was able to reduce the number of CFU/mL in biofilms and to cause structural alteration and cellular destruction, observed via SEM. A. colubrina showed low toxicity in the in vivo assay, having not affected the viability of the larvae at doses below 100mg/kg and high potential in the treatment of C. albicans infection. Considering its high antifungal potential, its low toxicity and potential to treatment of infections in in vivo model, A. colubrina extract is a strong candidate for development of a new agent for the treatment of oral candidiasis33CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ552562/2011-

Cardiovascular effects induced by the aqueous fraction of the ethanol extract of the stem of Solanum stipulaceum in rats

The cardiovascular effects induced by the aqueous fraction of the ethanol extract of the stem (AFS) of Solanum stipulaceum Roem. & Schult were studied in rats. In non-anesthetized rats, AFS injections produced significant and dosedependent hypotension associated with increase in heart rate. In isolated rat superior mesenteric rings, AFS was able to antagonize the contractions induced by phenylephrine and KCl. The vasorelaxant activity of AFS was not inhibited by either removal of vascular endothelium, L-NAME, atropine or indomethacine. In isolated rat atrial preparations, AFS produced concentration-related negative inotropic and chronotropic responses. These results suggest that the hypotensive effect of AFS is due to a peripheral vasodilation, which can not be attributed to the participation of vascular endothelium. Finally, AFS acts directly on the heart decreasing contractility and heart rate

The role of boundary conditions on the dynamics of green coffee beans in a rotated dryer

[EN] Coffee drying and roasting are usually performed in rotated dryers; therefore, the study of particle dynamics in this equipment is of great relevance to improve their efficiency and hence the quality of the final product. Thus, this work aimed to investigate experimentally and numerically the dynamics of coffee beans in a rotary dryer. The Euler-Euler model was employed to reproduce the particle velocity profile in the rolling regime under different boundary conditions. The results shown that the lower specularity coefficient (0.01), which characterizes the smooth wall and free slip condition, reproduced the bed behavior that most resembled the experimental one. On the other hand, the other coefficients (0.1 and 1.0) showed an increasing deformation in the bed surface, different from the observed experimental behavior. It was also verified that, as the filling degree increases, the bed surface deformation becomes more pronounced.The authors would like to thank FAPEMIG, CNPq and CAPES for the financial resources assigned to carry out this work.Machado, M.; Resende, I.; Lima, R.; Brandão, R.; Pivello, M.; Nascimento, S.; Duarte, C.... (2018). The role of boundary conditions on the dynamics of green coffee beans in a rotated dryer. En IDS 2018. 21st International Drying Symposium Proceedings. Editorial Universitat Politècnica de València. 331-338. https://doi.org/10.4995/IDS2018.2018.7455OCS33133

Unusual magnetic relaxation behavior in La0.5Ca0.5MnO3 and Nd0.5Sr0.5MnO3

We have carried out a systematic magnetic relaxation study, measured after applying and switching off a 5 T magnetic field to polycrystalline samples of La0.5Ca0.5MnO3 and Nd0.5Sr0.5MnO3. The long time logarithmic relaxation rate (LTLRR), decreased from 10 K to 150 K and increased from 150 K to 195 K in La0.5Ca0.5MnO3. This change in behavior was found to be related to the complete suppression of the antiferromagnetic phase above 150 K and in the presence of a 5 T magnetic field. At 195 K, the magnetization first decreased, and after a few minutes increased slowly as a function of time. Moreover, between 200 K and 245 K, the magnetization increased throughout the measured time span. The change in the slope of the curves, from negative to positive at about 200 K was found to be related to the suppression of antiferromagnetic fluctuations in small magnetic fields. A similar temperature dependence of the LTLRR was found for the Nd0.5Sr0.5MnO3 sample. However, the temperature where the LTLRR reached the minimum in Nd0.5Sr0.5MnO3 was lower than that of La0.5Ca0.5MnO3. This result agrees with the stronger ferromagnetic interactions that exist in Nd0.5Sr0.5MnO3 in comparison to La0.5Ca0.5MnO3. The above measurements suggested that the general temperature dependence of the LTLRR and the underlying physics were mainly independent of the particular charge ordering system considered. All relaxation curves could be fitted using a logarithmic law at long times. This slow relaxation was attributed to the coexistence of ferromagnetic and antiferromagnetic interactions between Mn ions, which produced a distribution of energy barriers.Comment: Accepted to PRB as a regular article, 10 figures, Scheduled Issue: 01 June 200

Comparative analysis of the secretome and interactome of Trypanosoma cruzi and Trypanosoma rangeli reveals species specific immune response modulating proteins

Chagas disease, a zoonosis caused by the flagellate protozoan Trypanosoma cruzi, is a chronic and systemic parasitic infection that affects ~5–7 million people worldwide, mainly in Latin America. Chagas disease is an emerging public health problem due to the lack of vaccines and effective treatments. According to recent studies, several T. cruzi secreted proteins interact with the human host during cell invasion. Moreover, some comparative studies with T. rangeli, which is non-pathogenic in humans, have been performed to identify proteins directly involved in the pathogenesis of the disease. In this study, we present an integrated analysis of canonical putative secreted proteins (PSPs) from both species. Additionally, we propose an interactome with human host and gene family clusters, and a phylogenetic inference of a selected protein. In total, we identified 322 exclusively PSPs in T. cruzi and 202 in T. rangeli. Among the PSPs identified in T. cruzi, we found several trans-sialidases, mucins, MASPs, proteins with phospholipase 2 domains (PLA2-like), and proteins with Hsp70 domains (Hsp70-like) which have been previously characterized and demonstrated to be related to T. cruzi virulence. PSPs found in T. rangeli were related to protozoan metabolism, specifically carboxylases and phosphatases. Furthermore, we also identified PSPs that may interact with the human immune system, including heat shock and MASP proteins, but in a lower number compared to T. cruzi. Interestingly, we describe a hypothetical hybrid interactome of PSPs which reveals that T. cruzi secreted molecules may be down-regulating IL-17 whilst T. rangeli may enhance the production of IL-15. These results will pave the way for a better understanding of the pathophysiology of Chagas disease and may ultimately lead to the identification of molecular targets, such as key PSPs, that could be used to minimize the health outcomes of Chagas disease by modulating the immune response triggered by T. cruzi infection

Relevamiento del carbón del maní: inóculo e intensidad de la enfermedad, campaña 2020-21

En el contexto de un Proyecto Local de INTA (PL328), un Proyecto disciplinario de INTA (I081) y un Convenio de Asistencia Técnica con la Fundación Maní Argentino, se trabajó articulando extensión e investigación para generar información útil, con la finalidad de fortalecer una economía regional clave para la provincia de Córdoba, como es la del maní, con el objetivo de mitigar el impacto de la enfermedad del carbón, causada por Thecaphora frezii.Instituto de Patología VegetalFil: Bernanrdi Lima, Nelson. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); ArgentinaFil: Bernanrdi Lima, Nelson. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Alcala, R. Fundación ArgenINTA. Delegación CIAP; ArgentinaFil: Brandimarte, Maria Soledad. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Monetti, Mariela. Instituto Nacional de Tecnología Agropecuaria (INTA).Estación Experimental Agropecuaria Manfredi. Agencia De Extensión Rural General Cabrera; ArgentinaFil: Toledo, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez. Agencia De Extensión Rural Río Cuarto; ArgentinaFil: Canale, Alejandra. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez. Agencia De Extensión Rural Río Cuarto; ArgentinaFil: Paredes, Juan Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); ArgentinaFil: Paredes, Juan Andrés. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Pérez, I.A. Fundación ArgenINTA. Delegación CIAP; ArgentinaFil: Rago, Alejandro Mario. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro de Investigaciones Agropecuarias (CIAP); ArgentinaFil: Rago, Alejandro Mario. Universidad Nacional de Río Cuarto (UNRC). Facultad de Agronomía y Veterinaria (FAV); ArgentinaFil: Margonari, Vanina Magdalena. Instituto Nacional de Tecnología Agropecuaria (INTA).Estación Experimental Agropecuaria Manfredi. Agencia De Extensión Rural Jesús María; ArgentinaFil: Conforto, Erica Cinthia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; ArgentinaFil: Conforto, Erica Cinthia. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Fitopatología y Modelización Agrícola (UFyMA); Argentin