7 research outputs found

    Self-efficacy beliefs amongst parents of young children : validation of a self-report measure

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    The self-efficacy belief (SEB) concept is discussed in the context of parenting. A questionnaire, the Echelle Globale du Sentiment de Competence Parentale (EGSCP), assessing several domain-specific SEBs and three related cognitive constructs, was developed with 705 French-speaking parents of 3- to 7-year-old children. The EGSCP displayed good psychometric properties. Age-related differences and differences between mothers and fathers illustrated the questionnaire's discriminative properties. Relations were also found between EGSCP and several criterion variables: support, satisfaction, self-esteem and stress, childrearing behavior, and children's social competence and behavior. The refinement of the SEB concept in the parenting context provides a more comprehensive view of both mothers' and fathers' cognition. The empirical and clinical implications of this are discussed

    Apert syndrome results from localised mutations of FGFR2 and is allelic with Crouzon syndrome

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    Apert syndrome is a distinctive human malformation comprising craniosynostosis and severe syndactyly of the hands and feet. We have identified specific missense substitutions involving adjacent amino acids (Ser252Trp and Pro253Arg) in the linker between the second and third extracellular immunoglobulin (Ig) domains of fibroblast growth factor receptor 2 (FGFR2) in all 40 unrelated cases of Apert syndrome studied. Crouzon syndrome, characterized by craniosynostosis but normal limbs, was previously shown to result from allelic mutations of the third Ig domain of FGFR2. The contrasting effects of these mutations provide a genetic resource for dissecting the complex effects of signal transduction through FGFRs in cranial and limb morphogenesis.Andrew O.m. Wilkie ; Sarah F. Slaney ; Michael Oldridge ; Michael D. Poole ; Geraldine J. Ashworth ; Anthony D. Hockley ; Richard D. Hayward ; David J. David ; Louise J. Pulleyn ; Paul Rutland ; Susan Malcolm ; Robin M. Winter ; William Reardo
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