65 research outputs found
Anomalous thickness dependence of the Hall effect in ultrathin Pb layers on Si(111)
The magnetoconductive properties of ultrathin Pb films deposited on Si(111)
are measured and compared with density-functional electronic band-structure
calculations on two-dimensional, free-standing, 1 to 8 monolayers thick Pb(111)
slabs. A description with free-standing slabs is possible because it turned out
that the Hall coefficient is independent of the substrate and of the
crystalline order in the film. We show that the oscillations in sign of the
Hall coefficient observed as a function of film thickness can be explained
directly from the thickness dependent variations of the electronic
bandstructure at the Fermi energy.Comment: 4 pages incl. 3 figures, RevTeX, to appear in Phys. Rev.
Aharonov-Bohm Interferometry with Interacting Quantum Dots: Spin Configurations, Asymmetric Interference Patterns, Bias-Voltage-Induced Aharonov-Bohm Oscillations, and Symmetries of Transport Coefficients
We study electron transport through multiply-connected mesoscopic geometries
containing interacting quantum dots. Our formulation covers both equilibrium
and non-equilibrium physics. We discuss the relation of coherent transport
channels through the quantum dot to flux-sensitive Aharonov-Bohm oscillations
in the total conductance of the device. Contributions to transport in first and
second order in the intrinsic line width of the dot levels are addressed in
detail. We predict an interaction-induced asymmetry in the amplitude of the
interference signal around resonance peaks as a consequence of incoherence
associated with spin-flip processes. This asymmetry can be used to probe the
total spin of the quantum dot. Such a probe requires less stringent
experimental conditions than the Kondo effect, which provides the same
information. We show that first-order contributions can be partially or even
fully coherent. This contrasts with the sequential-tunneling picture, which
describes first-order transport as a sequence of incoherent tunneling
processes. We predict bias-voltage induced Aharonov-Bohm oscillations of
physical quantities which are independent of flux in the linear-response
regime. Going beyond the Onsager relations we analyze the relations between the
space symmetry group of the setup and the flux-dependent non-linear
conductance.Comment: 22 pages, 11 figure
Optical properties of MgH2 measured in situ in a novel gas cell for ellipsometry/spectrophotometry
The dielectric properties of alpha-MgH2 are investigated in the photon energy
range between 1 and 6.5 eV. For this purpose, a novel sample configuration and
experimental setup are developed that allow both optical transmission and
ellipsometric measurements of a transparent thin film in equilibrium with
hydrogen. We show that alpha-MgH2 is a transparent, colour neutral insulator
with a band gap of 5.6 +/- 0.1 eV. It has an intrinsic transparency of about
80% over the whole visible spectrum. The dielectric function found in this work
confirms very recent band structure calculations using the GW approximation by
Alford and Chou [J.A. Alford and M.Y. Chou (unpublished)]. As Pd is used as a
cap layer we report also the optical properties of PdHx thin films.Comment: REVTeX4, 15 pages, 12 figures, 5 table
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3′-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7Ă—10-8, HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4Ă—10-8, HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4Ă—10-8, HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific associat
Fourpole properties of electro acoustic delay line with conventional and unconvectional transducers
Applied Science
- …