Influence of grain-refiner addition on the morphology of fe-bearing intermetallics in a semi-solid processed Al-Mg-Si alloy

© The Minerals, Metals & Materials Society and ASM International 2013The three-dimensional morphologies of the Fe-bearing intermetallics in a semisolid-processed Al-Mg-Si alloy were examined after extracting the intermetallics. α -AlFeSi and β-AlFeSi are the major Fe-bearing intermetallics. Addition of Al-Ti-B grain refiner typically promotes β-AlFeSi formation. β-AlFeSi was observed with a flat, plate-like morphology with angular edges in the alloy with and without grain refiner, whereas α -AlFeSi was observed as "flower"-like morphology in the alloy with grain refiner. © 2013 The Minerals, Metals & Materials Society and ASM International

The Structure of a Rigorously Conserved RNA Element within the SARS Virus Genome

We have solved the three-dimensional crystal structure of the stem-loop II motif (s2m) RNA element of the SARS virus genome to 2.7-Å resolution. SARS and related coronaviruses and astroviruses all possess a motif at the 3′ end of their RNA genomes, called the s2m, whose pathogenic importance is inferred from its rigorous sequence conservation in an otherwise rapidly mutable RNA genome. We find that this extreme conservation is clearly explained by the requirement to form a highly structured RNA whose unique tertiary structure includes a sharp 90° kink of the helix axis and several novel longer-range tertiary interactions. The tertiary base interactions create a tunnel that runs perpendicular to the main helical axis whose interior is negatively charged and binds two magnesium ions. These unusual features likely form interaction surfaces with conserved host cell components or other reactive sites required for virus function. Based on its conservation in viral pathogen genomes and its absence in the human genome, we suggest that these unusual structural features in the s2m RNA element are attractive targets for the design of anti-viral therapeutic agents. Structural genomics has sought to deduce protein function based on three-dimensional homology. Here we have extended this approach to RNA by proposing potential functions for a rigorously conserved set of RNA tertiary structural interactions that occur within the SARS RNA genome itself. Based on tertiary structural comparisons, we propose the s2m RNA binds one or more proteins possessing an oligomer-binding-like fold, and we suggest a possible mechanism for SARS viral RNA hijacking of host protein synthesis, both based upon observed s2m RNA macromolecular mimicry of a relevant ribosomal RNA fold

Shared Care, Elder and Family Member Skills Used to Manage Burden

Aim. The aim of this paper is to further develop the construct of Shared Care by comparing and contrasting it to related research, and to show how the construct can be used to guide research and practice. Background. While researchers have identified negative outcomes for family caregivers caused by providing care, less is known about positive aspects of family care for both members of a family dyad. Understanding family care relationships is important to nurses because family participation in the care of chronically ill elders is necessary to achieve optimal outcomes from nursing interventions. A previous naturalistic inquiry identified a new construct, Shared Care, which was used to describe a family care interaction that contributed to positive care outcomes. Methods. A literature review was carried out using the databases Medline, CINAHL, and Psych-info and the keywords home care, care receiver, disability, family, communication, decision-making and reciprocity. The results of the review were integrated to suggest how Shared Care could be used to study care difficulties and guide interventions. Results. The literature confirmed the importance of dyad relationships in family care. Shared Care extended previous conceptualizations of family care by capturing three critical components: communication, decision-making, and reciprocity. Shared Care provides a structure to expand the conceptualization of family care to include both members of a care dyad and account for positive and negative aspects of care. Conclusions. The extended view provided by the construct of Shared Care offers practitioners and scholars tools to use in the context of our ageing population to improve the effectiveness of family care relationships

Development of a Momentum Determined Electron Beam in the 1 -45 GeV Range

A beam line for electrons with energies in the range of 1 to 45 GeV, low contamination of hadrons and muons and high intensity up to 10^6 per accelerator spill at 27 GeV was setup at U70 accelerator in Protvino, Russia. A beam tagging system based on drift chambers with 160 micron resolution was able to measure relative electron beam momentum precisely. The resolution sigma_p p was 0.13% at 45 GeV where multiple scattering is negligible. This test beam setup provided the possibility to study properties of lead tungstate crystals (PbWO_4) for the BTeV experiment at Fermilab.Comment: 12 pages, 8 figures; work done by the BTeV Electromagnetic Calorimeter grou

Correlation of Beam Electron and LED Signal Losses under Irradiation and Long-term Recovery of Lead Tungstate Crystals

Radiation damage in lead tungstate crystals reduces their transparency. The calibration that relates the amount of light detected in such crystals to incident energy of photons or electrons is of paramount importance to maintaining the energy resolution the detection system. We report on tests of lead tungstate crystals, read out by photomultiplier tubes, exposed to irradiation by monoenergetic electron or pion beams. The beam electrons themselves were used to measure the scintillation light output, and a blue light emitting diode (LED) was used to track variations of crystals transparency. We report on the correlation of the LED measurement with radiation damage by the beams and also show that it can accurately monitor the crystals recovery from such damage.Comment: 9 pages, 6 figures, LaTeX2

Comparison of Radiation Damage in Lead Tungstate Crystals under Pion and Gamma Irradiation

Studies of the radiation hardness of lead tungstate crystals produced by the Bogoroditsk Techno-Chemical Plant in Russia and the Shanghai Institute of Ceramics in China have been carried out at IHEP, Protvino. The crystals were irradiated by a 40-GeV pion beam. After full recovery, the same crystals were irradiated using a $^{137}Cs$ $\gamma$-ray source. The dose rate profiles along the crystal length were observed to be quite similar. We compare the effects of the two types of radiation on the crystals light output.Comment: 10 pages, 8 figures, Latex 2e, 28.04.04 - minor grammatical change

LED Monitoring System for the BTeV Lead Tungstate Crystal Calorimeter Prototype

We report on the performance of a monitoring system for a prototype calorimeter for the BTeV experiment that uses Lead Tungstate crystals coupled with photomultiplier tubes. The tests were carried out at the 70 GeV accelerator complex at Protvino, Russia.Comment: 12 pages, 8 figures, LaTeX2e, revised versio

Design and performance of LED calibration system prototype for the lead tungstate crystal calorimeter

A highly stable monitoring system based on blue and red light emitting diodes coupled to a distribution network comprised of optical fibers has been developed for an electromagnetic calorimeter that uses lead tungstate crystals readout with photomultiplier tubes. We report of the system prototype design and on the results of laboratory tests. Stability better than 0.1% (r.m.s.) has been achieved during one week of prototype operation.Comment: 10 pages, 6 figures, LaTeX2